Browsing HMS Scholarly Articles by Keyword "O-GlcNAc"

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    • O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway 

      Ferrer, Christina M.; Lu, Tong Y.; Bacigalupa, Zachary A.; Katsetos, Christos D.; Sinclair, David A.; Reginato, Mauricio J. (2016)
      Tumors utilize aerobic glycolysis to support growth and invasion. However, the molecular mechanisms that link metabolism with invasion are not well understood. The nutrient sensor O-linked-β-N-acetylglucosamine (O-GlcNAc) ...