Browsing HMS Scholarly Articles by Keyword "ZEB1"

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    • MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells 

      Kharbanda, Akriti; Rajabi, Hasan; Jin, Caining; Alam, Maroof; Wong, Kwok-Kin; Kufe, Donald (Impact Journals LLC, 2014)
      Non-small cell lung cancers (NSCLCs) that harbor an oncogenic KRAS mutation are often associated with resistance to targeted therapies. The MUC1-C transmembrane protein is aberrantly overexpressed in NSCLCs and confers a ...