Browsing HMS Scholarly Articles by Keyword "antigen presenting cells"

Now showing items 1-2 of 2

    • Graft Site Microenvironment Determines Dendritic Cell Trafficking Through the CCR7-CCL19/21 Axis 

      Hua, Jing; Stevenson, William; Dohlman, Thomas H.; Inomata, Takenori; Tahvildari, Maryam; Calcagno, Narghes; Pirmadjid, Negar; Sadrai, Zahra; Chauhan, Sunil K.; Dana, Reza (The Association for Research in Vision and Ophthalmology, 2016)
      Purpose The graft site microenvironment has a profound effect on alloimmunity and graft survival. We aimed to study the kinetics and phenotype of trafficking antigen-presenting cells (APC) to the draining lymph nodes (DLNs) ...

    • The Role of Heat Shock Proteins in Antigen Cross Presentation 

      Murshid, Ayesha; Gong, Jianlin; Calderwood, Stuart K. (Frontiers Research Foundation, 2012)
      Heat shock proteins (HSPs) are molecular chaperones that bind tumor antigens and mediate their uptake into antigen presenting cells. HSP–antigen complexes are then directed toward either the MHC class I pathway through ...