Browsing HMS Scholarly Articles by Keyword "c-Jun N-terminal kinase signaling cascade"
Now showing items 1-2 of 2
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Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis
(Public Library of Science, 2013)Necroptosis is a regulated form of necrotic cell death that has been implicated in the pathogenesis of various diseases including intestinal inflammation and systemic inflammatory response syndrome (SIRS). In this work, ... -
Protein Kinase R Modulates c-Fos and c-Jun Signaling to Promote Proliferation of Hepatocellular Carcinoma with Hepatitis C Virus Infection
(Public Library of Science, 2013)Double-stranded RNA-activated protein kinase R (PKR) is known to be upregulated by hepatitis C virus (HCV) and overexpressed in hepatocellular carcinoma (HCC). However, the precise roles of PKR in HCC with HCV infection ...