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Alterations in brain structures underlying language function in young adults at high familial risk for schizophrenia
(Elsevier BV, 2012)
Introduction—Neuroanatomical and cognitive alterations typical of schizophrenia (SZ) patients are observed to a lesser extent in their adolescent and adult first-degree relatives, likely reflecting neurodevelopmental ...
Statistical analysis of fiber bundles using multi-tensor tractography: application to first-episode schizophrenia
(Elsevier BV, 2011)
This work proposes a new method to detect abnormalities in fiber bundles of first-episode (FE) schizophrenia patients. Existing methods have either examined a particular region of interest (ROI) or used voxel based morphometry ...
White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia
(Elsevier BV, 2013)
Background—Previous studies have shown that frontostriatal networks, especially those involving dorsolateral prefrontal cortex (DLPFC) and ventrolateral prefrontal cortex (VLPFC) mediate cognitive functions some of which ...
Clinical high risk and first episode schizophrenia: Auditory event-related potentials
(Elsevier BV, 2015)
The clinical high risk (CHR) period is a phase denoting a risk for overt psychosis during which subacute symptoms often appear, and cognitive functions may deteriorate. To compare biological indices during this phase with ...
Frequency and pattern of childhood symptom onset reported by first episode schizophrenia and clinical high risk youth
(Elsevier BV, 2014)
Background—Psychosis prevention and early intervention efforts in schizophrenia have focused increasingly on sub-threshold psychotic symptoms in adolescents and young adults. Although many youth report symptom onset prior ...
Excessive Extracellular Volume Reveals a Neurodegenerative Pattern in Schizophrenia Onset
(Society for Neuroscience, 2012)
Diffusion MRI has been successful in identifying the existence of white matter abnormalities in schizophrenia in vivo. However, the role of these abnormalities in the etiology of schizophrenia is not well understood. ...
Extensive white matter abnormalities in patients with first-episode schizophrenia: A diffusion tensor imaging (DTI) study
(Elsevier BV, 2013)
Background—Previous voxelwise Diffusion Tensor Imaging (DTI) investigations of white matter in first-episode schizophrenia (FESZ) have been limited to the analysis of Fractional Anisotropy (FA) and mean diffusivity (MD), ...