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Localized abnormalities in the cingulum bundle in patients with schizophrenia: A Diffusion Tensor tractography study
(Elsevier, 2014)
The cingulum bundle (CB) connects gray matter structures of the limbic system and as such has been implicated in the etiology of schizophrenia. There is growing evidence to suggest that the CB is actually comprised of a ...
Diffusion Tensor Imaging, Structural Connectivity, and Schizophrenia
(Hindawi Publishing Corporation, 2011)
A fundamental tenet of the “disconnectivity” theories of schizophrenia is that the disorder is ultimately caused by abnormal communication between spatially disparate brain structures. Given that the white matter fasciculi ...
Genetic contributions to changes of fiber tracts of ventral visual stream in 22q11.2 deletion syndrome
(Springer Science + Business Media, 2013)
Patients with 22q11.2 deletion syndrome (22q11.2DS) represent a population at high risk for
developing schizophrenia, as well as learning disabilities. Deficits in visuo-spatial memory are
thought to underlie some of the ...
Fiber geometry in the corpus callosum in schizophrenia: Evidence for transcallosal misconnection
(Elsevier BV, 2011)
Background—Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of ...
Decreased axial diffusivity within language connections: A possible biomarker of schizophrenia risk
(Elsevier BV, 2013)
Siblings of patients diagnosed with schizophrenia are at elevated risk for developing this disorder. The nature of such risk associated with brain abnormalities, and whether such abnormalities are similar to those observed ...
Alterations in brain structures underlying language function in young adults at high familial risk for schizophrenia
(Elsevier BV, 2012)
Introduction—Neuroanatomical and cognitive alterations typical of schizophrenia (SZ) patients are observed to a lesser extent in their adolescent and adult first-degree relatives, likely reflecting neurodevelopmental ...
Human middle longitudinal fascicle: variations in patterns of anatomical connections
(Springer Science + Business Media, 2012)
Based on high-resolution diffusion tensor magnetic resonance imaging (DTI) tractographic
analyses in thirty-nine healthy adult subjects we derived patterns of connections and measures of volume and biophysical parameters, ...
Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia
(Elsevier BV, 2013)
Introduction—The Middle Longitudinal Fascicle (MdLF) is a long association fiber connecting the superior temporal gyrus (STG) and temporal pole with the angular gyrus through the white matter of the STG, structures which ...
Statistical analysis of fiber bundles using multi-tensor tractography: application to first-episode schizophrenia
(Elsevier BV, 2011)
This work proposes a new method to detect abnormalities in fiber bundles of first-episode (FE) schizophrenia patients. Existing methods have either examined a particular region of interest (ROI) or used voxel based morphometry ...
White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia
(Elsevier BV, 2013)
Background—Previous studies have shown that frontostriatal networks, especially those involving dorsolateral prefrontal cortex (DLPFC) and ventrolateral prefrontal cortex (VLPFC) mediate cognitive functions some of which ...