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Diffusion Tensor Imaging, Structural Connectivity, and Schizophrenia
(Hindawi Publishing Corporation, 2011)
A fundamental tenet of the “disconnectivity” theories of schizophrenia is that the disorder is ultimately caused by abnormal communication between spatially disparate brain structures. Given that the white matter fasciculi ...
Fiber geometry in the corpus callosum in schizophrenia: Evidence for transcallosal misconnection
(Elsevier BV, 2011)
Background—Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of ...
Statistical analysis of fiber bundles using multi-tensor tractography: application to first-episode schizophrenia
(Elsevier BV, 2011)
This work proposes a new method to detect abnormalities in fiber bundles of first-episode (FE) schizophrenia patients. Existing methods have either examined a particular region of interest (ROI) or used voxel based morphometry ...
Voxel-based morphometry (VBM) studies in schizophrenia—can white matter changes be reliably detected with VBM?
(Elsevier BV, 2011)
Voxel-Based Morphometry (VBM) is a hypothesis-free, whole-brain, voxel-by-voxel analytic method that attempts to compare imaging data between populations. Schizophrenia studies have utilized this method to localize differences ...
Predicting inter-hemispheric transfer time from the diffusion properties of the corpus callosum in healthy individuals and schizophrenia patients: A combined ERP and DTI study
(Elsevier BV, 2011)
Background—Several theories of schizophrenia have emphasized the role of aberrant neural timing in the etiology of the disease, possibly as a consequence of conduction delays caused by structural damage to the white-matter ...
Stochastic tractography study of Inferior Frontal Gyrus anatomical connectivity in schizophrenia
(Elsevier BV, 2011)
Background—Abnormalities within language-related anatomical structures have been associated with clinical symptoms and with language and memory deficits in schizophrenia. Recent studies suggest disruptions in functional ...
White Matter Bundle Registration and Population Analysis Based on Gaussian Processes
(Springer Science + Business Media, 2011)
This paper proposes a method for the registration of white matter tract bundles traced from diffusion images and its extension to atlas generation. Our framework is based on a Gaussian process representation of tract density ...