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Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: A pilot study
(Elsevier BV, 2013)
For certain research questions related to long-term outcomes or to rare disorders, designing
prospective studies is impractical or prohibitively expensive. Such studies could instead utilize clinical and magnetic resonance ...
Prefrontal cortex, negative symptoms, and schizophrenia: an MRI study
(Elsevier BV, 2001)
The present study measured prefrontal cortical gray and white matter volume in chronic, male schizophrenic subjects who were characterized by a higher proportion of mixed or negative symptoms than previous patients that ...
Fornix Integrity and Hippocampal Volume in Male Schizophrenic Patients
(Elsevier BV, 2006)
Background: The hippocampus has been shown to be abnormal in schizophrenia. The fornix is one of the main fiber tracts connecting the hippocampus with other brain regions. Few studies have evaluated the fornix in schizophrenia, ...
An MRI study of temporal lobe abnormalities and negative symptoms in chronic schizophrenia
(Elsevier BV, 2002)
Previous magnetic resonance imaging (MRI) studies have reported various subtle brain abnormalities in schizophrenic patients, including temporal lobe abnormalities, which are of particular interest given the role of this ...
Clarifying the Origin of Biological Abnormalities in PTSD Through the Study of Identical Twins Discordant for Combat Exposure
(Wiley-Blackwell, 2006)
A biological abnormality found to be associated with post-traumatic stress disorder (PTSD) may be, among other things, a pre-trauma vulnerability factor, that is, it may have been present prior to the event’s occurrence ...
Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder
(Elsevier BV, 1996)
This study used quantitative volumetric magnetic resonance imaging techniques to explore the neuroanatomic correlates of chronic, combat-related posttraumatic stress disorder (PTSD) in seven Vietnam veterans with PTSD ...
MRI abnormalities of the hippocampus and cavum septi pellucidi in females with schizotypal personality disorder
(Elsevier BV, 2007)
Objective: This study examined MRI hippocampal volume and cavum septi pellucidi (CSP) in female subjects with schizotypal personality disorder (SPD) and comparison subjects. Method: MRI was performed on 20 SPD and 29 ...
A quantitative MR measure of the fornix in schizophrenia
(Elsevier BV, 2001)
Some cognitive disturbances accompanying schizophrenia may be due to abnormalities in the thalamus and components of the limbic system. The fornix is an important white-matter relay pathway connecting these structures and ...
Configural Cue Performance in Identical Twins Discordant for Posttraumatic Stress Disorder: Theoretical Implications for the Role of Hippocampal Function
(Elsevier BV, 2007)
Background: A significant subgroup of individuals with posttraumatic stress disorder (PTSD) exhibits chronic, unremitting symptomatology that has also been associated with smaller hippocampal volume. The hippocampus plays ...
Amygdala–hippocampal shape differences in schizophrenia: the application of 3D shape models to volumetric MR data
(Elsevier BV, 2002)
Evidence suggests that some structural brain abnormalities in schizophrenia are neurodevelopmental in origin. There is also growing evidence to suggest that shape deformations in brain structure may reflect abnormalities ...