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Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
(Nature Publishing Group, 2012)
Lymph node stromal cells (LNSCs) closely regulate immunity and self-tolerance, yet key aspects of their biology remain poorly illuminated. Comparative transcriptomic analyses of murine LNSC subsets revealed expression of ...
Effect of substrate stiffness on early human embryonic stem cell differentiation
(BioMed Central, 2013)
Background: The pluripotency and self renewing properties of human embryonic stem cells (hESC) make them a valuable tool in the fields of developmental biology, pharmacology and regenerative medicine. Therefore, there ...
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
(Springer Nature, 2012)
The blood vessels of cancerous tumours are leaky1–3 and poorly organized4–7. This can increase the interstitial fluid pressure (IFP) inside tumours and reduce blood supply to them, which impairs drug delivery8–9. Anti-angiogenic ...