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Maternal Plasma 25-Hydroxyvitamin D Concentrations and the Risk for Gestational Diabetes Mellitus
(Public Library of Science, 2008)
Background: Evidence is accumulating for a role of vitamin D in maintaining normal glucose homeostasis. However, studies that prospectively examined circulating concentrations of 25-hydroxyvitamin D (25-[OH] D) in relation ...
Combined impact of lifestyle factors on mortality: prospective cohort study in US women
(BMJ Publishing Group Ltd., 2008)
Objective: To evaluate the impact of combinations of lifestyle factors on mortality in middle aged women. Design: Prospective cohort study. Setting: Nurses’ health study, United States. Participants: 77 782 women aged 34 ...
A Genome-Wide Association Study Identifies Novel Alleles Associated with Hair Color and Skin Pigmentation
(Public Library of Science, 2008)
We conducted a multi-stage genome-wide association study of natural hair color in more than 10,000 men and women of European ancestry from the United States and Australia. An initial analysis of 528,173 single nucleotide ...
Carotid Artery Intima-media Thickness, Carotid Plaque and Coronary Heart Disease and Stroke in Chinese
(Public Library of Science, 2008)
Background: Our aim was to prospectively investigate the association between carotid artery intima-media thickness (IMT) as well as carotid plaque and incidence of coronary heart disease (CHD) and stroke in Chinese, among ...
Alcohol Consumption, Mediating Biomarkers, and Risk of Type 2 Diabetes Among Middle-Aged Women
(American Diabetes Association, 2008)
OBJECTIVE—The purpose of this study was to investigate whether adiponectin concentrations and biomarkers of inflammation, endothelial dysfunction, and insulin resistance mediate the association between alcohol consumption ...
Common Variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE Genes Are Associated With Type 2 Diabetes and Impaired Fasting Glucose in a Chinese Han Population
(American Diabetes Association, 2008)
OBJECTIVE— Genome-wide association studies have identified common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, HHEX/IDE, EXT2, and LOC387761 loci that significantly increase the risk of type 2 diabetes. We aimed to ...
Fat Mass–and Obesity-Associated (FTO) Gene Variant Is Associated With Obesity
(American Diabetes Association, 2008)
OBJECTIVE—To examine the longitudinal association of fat mass–and obesity-associated (FTO) variant with obesity, circulating adipokine levels, and FTO expression in various materials from human and mouse. RESEARCH DESIGN ...