Search
Now showing items 1-10 of 25
E-Selectin Mediates Immune Cell Trafficking in Corneal Transplantation
(Ovid Technologies (Wolters Kluwer Health), 2016)
Background
Immune rejection continues to threaten all tissue transplants. Here we sought to determine whether P- and E- selectin mediate T cell recruitment in corneal transplantation and whether their blockade can reduce ...
Degeneration and Regeneration of Subbasal Corneal Nerves after Infectious Keratitis
(Elsevier BV, 2015)
Purpose
To investigate the longitudinal alterations of subbasal corneal nerves in patients with infectious keratitis (IK) during acute phase, cessation of treatment and recovery phase by in vivo confocal microscopy ...
Topical Interleukin 1 Receptor Antagonist for Treatment of Dry Eye Disease
(American Medical Association (AMA), 2013)
Importance
The immunopathogenic mechanisms of dry eye disease (DED), one of the most common ophthalmic conditions, is incompletely understood. Data from this prospective, double-masked, randomized trial demonstrate that ...
What is the Value of Incorporating Tear Osmolarity Measurement in Assessing Patient Response to Therapy in Dry Eye Disease?
(Elsevier BV, 2014)
Purpose
To evaluate the correlation between changes in tear osmolarity, symptoms, and corneal fluorescein staining in patients with dry eye disease (DED).
Design
Retrospective, clinic-based cohort study.
Methods
In ...
Inflammation and the Nervous System: The Connection in the Cornea in Patients with Infectious Keratitis
(Association for Research in Vision and Ophthalmology (ARVO), 2011)
Purpose.
To study the density and morphologic characteristics of epithelial dendritic cells, as correlated to subbasal corneal nerve alterations in acute infectious keratitis (IK) by in vivo confocal microscopy ...
Unilateral Herpes Zoster Ophthalmicus Results in Bilateral Corneal Nerve Alteration
(Elsevier BV, 2013)
Purpose
Herpes zoster ophthalmicus (HZO), thought to be a unilateral disease, results in loss of corneal sensation, leading to neurotrophic keratopathy. This study aimed to analyze bilateral corneal nerve changes in ...
Contralateral Clinically Unaffected Eyes of Patients With Unilateral Infectious Keratitis Demonstrate a Sympathetic Immune Response
(Association for Research in Vision and Ophthalmology (ARVO), 2015)
Purpose
To analyze the contralateral unaffected eyes of patients with microbial keratitis (MK) for any immune cell or nerve changes by laser in vivo confocal microscopy (IVCM).
Methods
A prospective study was ...
Reduced Corneal Endothelial Cell Density in Patients With Dry Eye Disease
(Elsevier BV, 2015)
Purpose
To evaluate corneal endothelial cell density (ECD) in patients with dry eye disease (DED) compared to an age-matched control group.
Design
Cross-sectional, controlled study
Methods
This study included ...
Corneal Epithelial Immune Dendritic Cell Alterations in Subtypes of Dry Eye Disease: A Pilot In Vivo Confocal Microscopic Study
(Association for Research in Vision and Ophthalmology (ARVO), 2015)
Purpose
To evaluate density and morphology of corneal epithelial immune dendritic cells (DCs) in different subtypes of dry eye disease (DED) using in vivo confocal microscopy (IVCM).
Methods
This retrospective ...
In Vivo Confocal Microscopic Changes of the Corneal Epithelium and Stroma in Patients With Herpes Zoster Ophthalmicus
(Elsevier BV, 2015)
Purpose
To analyze the density and morphology of corneal epithelial cells and keratocytes by in vivo confocal microscopy (IVCM) in patients with herpes zoster ophthalmicus (HZO) as associated with corneal innervation. ...