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Deformable organisms for automatic medical image analysis
(Elsevier BV, 2002)
We introduce a new approach to medical image analysis that combines deformable model methodologies with concepts from the field of artificial life. In particular, we propose ‘deformable organisms’, autonomous agents whose ...
A new statistical method for testing hypotheses of neuropsychological/MRI relationships in schizophrenia: partial least squares analysis
(Elsevier BV, 2002)
We applied partial least squares (PLS) as a novel multivariate statistical technique to examine neuropsychological correlates of magnetic resonance imaging (MRI) measures of brain volumes in a well studied sample of 15 ...
Voxel-Based Morphometric Analysis of Gray Matter in First Episode Schizophrenia
(Elsevier BV, 2002)
Voxel-based morphometry (VBM) may afford a more rapid and extensive survey of gray matter abnormalities in schizophrenia than manually drawn region of interest (ROI) analysis, the current gold standard in structural MRI. ...
MRI Study of Caudate Nucleus Volume and Its Cognitive Correlates in Neuroleptic-Naive Patients With Schizotypal Personality Disorder
(American Psychiatric Publishing, 2002)
Objective: “Cognitive” circuits anatomically link the frontal lobe to subcortical structures; therefore, pathology in any of the core components of these circuits, such as in the caudate nucleus, may result in neurobehavioral ...
Uncinate Fasciculus Findings in Schizophrenia: A Magnetic Resonance Diffusion Tensor Imaging Study
(American Psychiatric Publishing, 2002)
Objective: Disruptions in connectivity between the frontal and temporal lobes may explain some of the symptoms observed in schizophrenia. Conventional magnetic resonance imaging (MRI) studies, however, have not shown ...
The Effect of Background Noise on P300 to Suprathreshold Stimuli
(Wiley-Blackwell, 2002)
Both the amplitude and latency of P300 vary with changes in stimulus parameters. Stimuli at intensities or pitch separations near threshold evoke a smaller and later P300. P300 is also affected by extraneous stimulus ...
Semantic Dysfunction in Women With Schizotypal Personality Disorder
(American Psychiatric Publishing, 2002)
Objective: This study examined whether early or late processes in semantic networks were abnormal in women with a diagnosis of schizotypal personality disorder. The N400 component of the EEG event-related potentials was ...
Shape Differences in the Corpus Callosum in First-Episode Schizophrenia and First-Episode Psychotic Affective Disorder
(American Psychiatric Publishing, 2002)
Objective: The corpus callosum, the largest white matter tract in the brain, is a midline structure associated with the formation of the hippocampus, septum pellucidum, and cingulate cortex, which have been implicated in ...
An MRI study of temporal lobe abnormalities and negative symptoms in chronic schizophrenia
(Elsevier BV, 2002)
Previous magnetic resonance imaging (MRI) studies have reported various subtle brain abnormalities in schizophrenic patients, including temporal lobe abnormalities, which are of particular interest given the role of this ...
Diffusion Tensor Imaging and Its Application to Neuropsychiatric Disorders
(Ovid Technologies (Wolters Kluwer Health), 2002)
Magnetic resonance diffusion tensor imaging (DTI) is a new technique that can be used to visualize and measure the diffusion of water in brain tissue; it is particularly useful for evaluating white matter abnormalities. ...