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Structural Analysis of Glutaredoxin Domain of Mus Musculus Thioredoxin Glutathione Reductase
(Public Library of Science, 2012)
Thioredoxin glutathione reductase (TGR) is a member of the mammalian thioredoxin reductase family that has a monothiol glutaredoxin (Grx) domain attached to the thioredoxin reductase module. Here, we report a structure of ...
Characterization of Mammalian Selenoprotein O: A Redox-Active Mitochondrial Protein
(Public Library of Science, 2014)
Selenoproteins exhibit diverse biological functions, most of which are associated with redox control. However, the functions of approximately half of mammalian selenoproteins are not known. One such protein is Selenoprotein ...
Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes
(Public Library of Science, 2012)
Background: Selenium is an essential trace element in mammals due to its presence in proteins in the form of selenocysteine (Sec). Human genome codes for 25 Sec-containing protein genes, and mouse and rat genomes for 24. ...