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Signaling Role of Prokineticin 2 on the Estrous Cycle of Female Mice
(Public Library of Science, 2014)
The possible signaling role of prokineticin 2 (PK2) and its receptor, prokineticin receptor 2 (PKR2), on female reproduction was investigated. First, the expression of PKR2 and its co-localization with estrogen receptor ...
High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons
(Public Library of Science, 2014)
The formation of synapses, the specialized points of chemical communication between neurons, is a highly regulated developmental process fundamental to establishing normal brain circuitry. Perturbations of synapse formation ...
Synergistic Effects of 3D ECM and Chemogradients on Neurite Outgrowth and Guidance: A Simple Modeling and Microfluidic Framework
(Public Library of Science, 2014)
During nervous system development, numerous cues within the extracellular matrix microenvironment (ECM) guide the growing neurites along specific pathways to reach their intended targets. Neurite motility is controlled by ...
Effects of Domain-Specific Noise on Visual Motion Processing in Schizophrenia
(Public Library of Science, 2014)
Background: Visual perception impairments in schizophrenia stem from abnormal information processing. Information processing requires neural response to a stimulus (signal) against a backdrop of 1) random variation in ...
Elevated Plasma Total Cholesterol Level Is Associated with the Risk of Asymptomatic Intracranial Arterial Stenosis
(Public Library of Science, 2014)
Background: Intracranial arterial stenosis (ICAS) is one of the most common causes of stroke, and dyslipidemia was one of the most common risk factors related to ICAS. However, the correlation between the plasma total ...
Increasing fMRI Sampling Rate Improves Granger Causality Estimates
(Public Library of Science, 2014)
Estimation of causal interactions between brain areas is necessary for elucidating large-scale functional brain networks underlying behavior and cognition. Granger causality analysis of time series data can quantitatively ...
Elemental Spatial and Temporal Association Formation in Left Temporal Lobe Epilepsy
(Public Library of Science, 2014)
The mesial temporal lobe (MTL) is typically understood as a memory structure in clinical settings, with the sine qua non of MTL damage in epilepsy being memory impairment. Recent models, however, understand memory as one ...
Dissociable Genetic Contributions to Error Processing: A Multimodal Neuroimaging Study
(Public Library of Science, 2014)
Background: Neuroimaging studies reliably identify two markers of error commission: the error-related negativity (ERN), an event-related potential, and functional MRI activation of the dorsal anterior cingulate cortex ...
Are Maternal Social Networks and Perceptions of Trust Associated with Suspected Autism Spectrum Disorder in Offspring? A Population-Based Study in Japan
(Public Library of Science, 2014)
Objective: To investigate the associations of maternal social networks and perceptions of trust with the prevalence of suspected autism spectrum disorders in 18-month-old offspring in Japan. Methods: Questionnaires included ...
Arousal vs. Relaxation: A Comparison of the Neurophysiological and Cognitive Correlates of Vajrayana and Theravada Meditative Practices
(Public Library of Science, 2014)
Based on evidence of parasympathetic activation, early studies defined meditation as a relaxation response. Later research attempted to categorize meditation as either involving focused or distributed attentional systems. ...