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A new statistical method for testing hypotheses of neuropsychological/MRI relationships in schizophrenia: partial least squares analysis
(Elsevier BV, 2002)
We applied partial least squares (PLS) as a novel multivariate statistical technique to examine neuropsychological correlates of magnetic resonance imaging (MRI) measures of brain volumes in a well studied sample of 15 ...
Local white matter geometry from diffusion tensor gradients
(Elsevier BV, 2010)
We introduce a mathematical framework for computing geometrical properties of white matter fibres directly from diffusion tensor fields. The key idea is to isolate the portion of the gradient of the tensor field corresponding ...
Combining ERP and Structural MRI Information in First Episode Schizophrenia and Bipolar Disorder
(SAGE Publications, 2008)
The electrical activity in the electroencephalogram (EEG) and the event-related potentials extracted from the EEG provide the greatest temporal resolution for examining brain function. When coupled with the high spatial ...
Schizotypal personality disorder and MRI abnormalities of temporal lobe gray matter
(Elsevier BV, 1999)
Background: Structural MRI data indicate schizophrenics have reduced left-sided temporal lobe gray matter volumes, especially in the superior temporal gyrus (STG) and medial temporal lobe. Our data further suggest a ...
MRI anatomy of schizophrenia
(Elsevier BV, 1999)
Structural magnetic resonance imaging (MRI) data have provided much evidence in support of our current view that schizophrenia is a brain disorder with altered brain structure, and consequently involving more than a simple ...
CNTNAP2 polymorphisms and structural brain connectivity: A diffusion-tensor imaging study
(Elsevier BV, 2013)
CNTNAP2 is a gene on chromosome 7 that has shown associations with autism andschizophrenia, and there is evidence that it plays an important role for neuronal synchronization and brain connectivity. In this study, we ...
An MRI study of temporal lobe abnormalities and negative symptoms in chronic schizophrenia
(Elsevier BV, 2002)
Previous magnetic resonance imaging (MRI) studies have reported various subtle brain abnormalities in schizophrenic patients, including temporal lobe abnormalities, which are of particular interest given the role of this ...
Altered orbitofrontal sulcogyral pattern in schizophrenia
(Oxford University Press (OUP), 2007)
Orbitofrontal alteration in schizophrenia has not been well characterized, likely due to marked anatomical variability. To investigate the presence of such alterations, we evaluated the sulcogyral pattern of this ‘H-shaped’ ...
A quantitative MR measure of the fornix in schizophrenia
(Elsevier BV, 2001)
Some cognitive disturbances accompanying schizophrenia may be due to abnormalities in the thalamus and components of the limbic system. The fornix is an important white-matter relay pathway connecting these structures and ...
Evidence for white matter abnormalities in schizophrenia
(Ovid Technologies (Wolters Kluwer Health), 2005)
Purpose of review: The purpose of this review is to highlight important recent imaging, histological, and genetic findings relevant to white matter abnormalities in schizophrenia. It is cast within the context of research ...