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Localized abnormalities in the cingulum bundle in patients with schizophrenia: A Diffusion Tensor tractography study
(Elsevier, 2014)
The cingulum bundle (CB) connects gray matter structures of the limbic system and as such has been implicated in the etiology of schizophrenia. There is growing evidence to suggest that the CB is actually comprised of a ...
Fiber geometry in the corpus callosum in schizophrenia: Evidence for transcallosal misconnection
(Elsevier BV, 2011)
Background—Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of ...
Attentional Control and Intelligence: MRI Orbital Frontal Gray Matter and Neuropsychological Correlates
(Hindawi Publishing Corporation, 2015)
Attentional control is a key function of working memory that is hypothesized to play an important role in psychometric intelligence. To test the neuropsychological underpinnings of this hypothesis, we examined full-scale ...
Disruption of function–structure coupling in brain regions sub-serving self monitoring in schizophrenia
(Elsevier BV, 2013)
Deficits in self monitoring are a core feature of cognitive dysfunction in schizophrenia, and may be the basis for disturbances of self and lack of insight, ultimately impacting social functioning. However, the functional ...
Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia
(Elsevier BV, 2014)
Although diffusion tensor imaging (DTI) studies have reported fractional anisotropy (FA) abnormalities in multiple white matter (WM) regions in schizophrenia, relationship between abnormal FA and negative symptoms has not ...
Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia
(Elsevier BV, 2010)
The dorsolateral prefrontal cortex (DLPFC) is a brain region that has figured prominently in studies of schizophrenia and working memory, yet the exact neuroanatomical localization of this brain region remains to be defined. ...
Comparing prefrontal gray and white matter contributions to intelligence and decision making in schizophrenia and healthy controls.
(American Psychological Association (APA), 2010)
We examined the relationship between neuropsychological performance and magnetic resonance imaging (MRI) of the orbital frontal cortex (OFC) and diffusion tensor imaging (DTI) of the cingulum bundle (CB) within groups of ...
Anterior limb of the internal capsule in schizophrenia: a diffusion tensor tractography study
(Springer Science + Business Media, 2012)
Thalamo-cortical feedback loops play a key role in the processing and coordination of processing and integration of perceptual inputs and outputs, and disruption in this connection has long been hypothesized to contribute ...
Quantitative Volumetric MRI Study of the Cerebellum and Vermis in Schizophrenia: Clinical and Cognitive Correlates
(American Psychiatric Publishing, 2016-09-14)
Objective: Recent evidence suggests that the cerebellum may play a role in higher cognitive functions and, therefore, may play an important role in schizophrenia. Method: The authors used magnetic resonance imaging to ...
Corpus Callosum Abnormalities and Their Association with Psychotic Symptoms in Patients with Schizophrenia
(Elsevier BV, 2010)
Background—Whilst the neuroanatomical underpinnings of the functional brain disconnectivity observed in patients with schizophrenia remain elusive, white matter fiber bundles of the brain are a likely candidate given that ...