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Localized abnormalities in the cingulum bundle in patients with schizophrenia: A Diffusion Tensor tractography study
(Elsevier, 2014)
The cingulum bundle (CB) connects gray matter structures of the limbic system and as such has been implicated in the etiology of schizophrenia. There is growing evidence to suggest that the CB is actually comprised of a ...
Maximum Entropy Estimation of Glutamate and Glutamine in MR Spectroscopic Imaging
(Springer Science + Business Media, 2014)
Magnetic resonance spectroscopic imaging (MRSI) is often used to estimate the concentration of several brain metabolites. Abnormalities in these concentrations can indicate specific pathology, which can be quite useful in ...
Fiber geometry in the corpus callosum in schizophrenia: Evidence for transcallosal misconnection
(Elsevier BV, 2011)
Background—Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of ...
Estimation of Extracellular Volume from Regularized Multi-shell Diffusion MRI
(Springer Science + Business Media, 2012)
Diffusion MRI measures micron scale displacement of water molecules, providing unique insight into microstructural tissue architecture. However, current practical image resolution is in the millimeter scale, and thus ...
Human middle longitudinal fascicle: variations in patterns of anatomical connections
(Springer Science + Business Media, 2012)
Based on high-resolution diffusion tensor magnetic resonance imaging (DTI) tractographic
analyses in thirty-nine healthy adult subjects we derived patterns of connections and measures of volume and biophysical parameters, ...
Statistical analysis of fiber bundles using multi-tensor tractography: application to first-episode schizophrenia
(Elsevier BV, 2011)
This work proposes a new method to detect abnormalities in fiber bundles of first-episode (FE) schizophrenia patients. Existing methods have either examined a particular region of interest (ROI) or used voxel based morphometry ...
Local white matter geometry from diffusion tensor gradients
(Elsevier BV, 2010)
We introduce a mathematical framework for computing geometrical properties of white matter fibres directly from diffusion tensor fields. The key idea is to isolate the portion of the gradient of the tensor field corresponding ...
Stochastic tractography study of Inferior Frontal Gyrus anatomical connectivity in schizophrenia
(Elsevier BV, 2011)
Background—Abnormalities within language-related anatomical structures have been associated with clinical symptoms and with language and memory deficits in schizophrenia. Recent studies suggest disruptions in functional ...
On Describing Human White Matter Anatomy: The White Matter Query Language
(Springer Science + Business Media, 2013)
The main contribution of this work is the careful syntactical definition of major white matter tracts in the human brain based on a neuroanatomist’s expert knowledge. We present a technique to formally describe white matter ...
A Geometry-Based Particle Filtering Approach to White Matter Tractography
(Springer Science + Business Media, 2010)
We introduce a fibre tractography framework based on a particle filter which estimates a local geometrical model of the underlying white matter tract, formulated as a `streamline flow' using generalized helicoids. The ...