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Widespread white matter degeneration preceding the onset of dementia
(Elsevier BV, 2015)
Background—Brain atrophy in subjects with mild cognitive impairment (MCI) introduces partial volume effects, limiting the sensitivity of diffusion tensor imaging to white matter microstructural degeneration. Appropriate ...
Comparing free water imaging and magnetization transfer measurements in schizophrenia
(Elsevier BV, 2015)
Diffusion weighted imaging (DWI) has been extensively used to study the microarchitecture of white matter in schizophrenia. However, popular DWI-derived measures such as fractional anisotropy (FA) may be sensitive to many ...
Applying a free-water correction to diffusion imaging data uncovers stress-related neural pathology in depression
(Elsevier, 2015)
Diffusion tensor imaging (DTI) holds promise for developing our understanding of white-matter pathology in major depressive disorder (MDD). Variable findings in DTI-based investigations of MDD, however, have thwarted ...