Browsing Harvard T.H. Chan School of Public Health by Title
Now showing items 3838-3857 of 6618
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Machine Learning Models for Neisseria gonorrhoeae Antimicrobial Susceptibility Tests
(2022)Neisseria gonorrhoeae is an urgent public health threat due to the emergence of antibiotic resistance. As most isolates in the US are susceptible to at least one antibiotic, rapid molecular antimicrobial susceptibility ... -
Macronutrient Composition and Plasma Metabolites in Relation to Cardiometabolic Disease
(2018-07-30)The connection between macronutrient composition, metabolic pathways, and cardiometabolic disease has been a popular target of investigation. However, there exist large research gaps relating to macronutrient composition, ... -
Macrophage Mal1 Deficiency Suppresses Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice by Activating Peroxisome Proliferator-Activated Receptor-γ–Regulated Genes
(Ovid Technologies (Wolters Kluwer Health), 2011-06) -
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis
(BioMed Central, 2006)Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by destruction of bone and cartilage, which is mediated, in part, by synovial fibroblasts. Matrix metalloproteinases (MMPs) are a large family of ... -
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
(BioMed Central, 2014)We propose the Model-based Analysis of Genome-wide CRISPR/Cas9 Knockout (MAGeCK) method for prioritizing single-guide RNAs, genes and pathways in genome-scale CRISPR/Cas9 knockout screens. MAGeCK demonstrates better ... -
Magnesium intake, plasma C-peptide, and colorectal cancer incidence in US women: a 28-year follow-up study
(Nature Publishing Group, 2012)Background: Laboratory studies suggest a possible role of magnesium intake in colorectal carcinogenesis but epidemiological evidence is inconclusive. Method: We tested magnesium–colorectal cancer hypothesis in the Nurses' ... -
Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III
(BioMed Central, 2013)Background: Magnesium plays an essential role in the synthesis and metabolism of vitamin D and magnesium supplementation substantially reversed the resistance to vitamin D treatment in patients with magnesium-dependent ... -
A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever
(Nature Publishing Group, 2016)There is currently no widely available optimal assay for diagnosing patients with enteric fever. Here we present a novel assay designed to detect amplified Salmonella nucleic acid (mRNA) using magneto-DNA probes and a ... -
Magnitude and Frequency of Cytotoxic T-Lymphocyte Responses: Identification of Immunodominant Regions of Human Immunodeficiency Virus Type 1 Subtype C
(American Society for Microbiology, 2002)A systematic analysis of immune responses on a population level is critical for a human immunodeficiency virus type 1 (HIV-1) vaccine design. Our studies in Botswana on (i) molecular analysis of the HIV-1 subtype C (HIV-1C) ... -
Major Copy Proportion Analysis of Tumor Samples Using SNP Arrays
(BioMed Central, 2008)Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays have been developed for high-throughput ... -
Major depressive disorder prevalence and risk factors among Syrian asylum seekers in Greece
(Springer Nature, 2018)Background Over one million Syrian asylum seekers have travelled to Greece with the ultimate aim of reaching other countries in western Europe. Depression prevalence and associated sociodemographic and displacement ... -
Major Dietary Patterns and Cardiovascular Risk Factors among Young Brazilian Adults
(Springer-Verlag, 2011)Purpose: Diet is one of the most important modifiable risk factors for cardiovascular diseases. The scientific literature has consistently shown the effects of certain diets on health; however, given the variety of cultures ... -
Major Dietary Patterns in Relation to General and Central Obesity among Chinese Adults
(MDPI, 2015)Limited evidence exists for the association between diet pattern and obesity phenotypes among Chinese adults. In the present study, we analyzed the cross-sectional data from 474,192 adults aged 30–79 years from the China ... -
Major Dietary Protein Sources and Risk of Coronary Heart Disease in Women
(American Heart Association, 2010)Background-With the exception of fish, few major dietary protein sources have been studied in relation to the development of coronary heart disease (CHD). Our objective was to examine the relation between foods that are ... -
Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies
(Oxford University Press, 2009)Background: Saturated fatty acid (SFA) intake increases plasma LDL-cholesterol concentrations; therefore, intake should be reduced to prevent coronary heart disease (CHD). Lower habitual intakes of SFAs, however, require ... -
Making Stillbirths Count, Making Numbers Talk - Issues in Data collection for Stillbirths
(BioMed Central, 2009)Background: Stillbirths need to count. They constitute the majority of the world's perinatal deaths and yet, they are largely invisible. Simply counting stillbirths is only the first step in analysis and prevention. From ... -
Malaria Control in South Africa 2000–2010: Beyond MDG6
(BioMed Central, 2012)Background: Malaria is one of the key targets within Goal 6 of the Millennium Development Goals (MDGs), whereby the disease needs to be halted and reversed by the year 2015. Several other international targets have been ... -
Malaria Incidence Rates from Time Series of 2-Wave Panel Surveys
(Public Library of Science, 2016)Methodology to estimate malaria incidence rates from a commonly occurring form of interval-censored longitudinal parasitological data—specifically, 2-wave panel data—was first proposed 40 years ago based on the theory of ... -
Malaria infection does not affect the sensitivity of peripheral receptor neurons in Anopheles stephensi
(BioMed Central, 2013)Background: Mosquitoes transmit many important diseases including malaria, dengue and yellow fever. Disease transmission from one vertebrate host to another depends on repeated blood feedings by single mosquitoes. In order ...