Browsing SPH Scholarly Articles by Title
Now showing items 1069-1088 of 6362
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Chromatin States Accurately Classify Cell Differentiation Stages
(Public Library of Science, 2012)Gene expression is controlled by the concerted interactions between transcription factors and chromatin regulators. While recent studies have identified global chromatin state changes across cell-types, it remains unclear ... -
Chronic effects of temperature on mortality in the Southeastern USA using satellite-based exposure metrics
(Nature Publishing Group, 2016)Climate change may affect human health, particularly for elderly individuals who are vulnerable to temperature changes. While many studies have investigated the acute effects of heat, only a few have dealt with the chronic ... -
Chronic enrichment of hepatic ER-mitochondria contact sites leads to calcium dependent mitochondrial dysfunction in obesity
(2015)Proper function of the endoplasmic reticulum (ER) and mitochondria is critical for cellular homeostasis, and dysfunction at either site has been linked to pathophysiological states including metabolic diseases. Although ... -
Chronic Exposure to Fine Particles and Mortality: An Extended Follow-up of the Harvard Six Cities Study from 1974 to 2009
(National Institute of Environmental Health Sciences, 2012)Background: Epidemiologic studies have reported associations between fine particles (aerodynamic diameter ≤ 2.5 µm; PM:2.5) and mortality. However, concerns have been raised regarding the sensitivity of the results to model ... -
Chronic Fine and Coarse Particulate Exposure, Mortality, and Coronary Heart Disease in the Nurses’ Health Study
(National Institute of Environmental Health Sciences, 2009)Background: The relationship of fine particulate matter < 2.5 μm in diameter (PM2.5) air pollution with mortality and cardiovascular disease is well established, with more recent long-term studies reporting larger effect ... -
Chronic Insufficient Sleep and Diet Quality: Contributors to Childhood Obesity
(2015)Objective: To examine associations of chronic insufficient sleep with diet, and whether diet explains the sleep-adiposity relationship. Methods: In Project Viva, 1,046 parents reported children’s sleep duration at 6m and ... -
Chronic Lung Function Decline in Cotton Textile Workers: Roles of Historical and Recent Exposures to Endotoxin
(National Institute of Environmental Health Sciences, 2010)Background: Long-term occupational exposure to cotton dust that contains endotoxin is associated with chronic respiratory symptoms and excessive decline in forced expiratory volume in 1 sec (FEV1), but the mechanisms of ... -
Chronic obstructive pulmonary disease and heart rate variability: a literature update
(BioMed Central, 2014)Background: The literature indicates that chronic obstructive pulmonary disease (COPD) affects cardiac autonomic control. In this study, we conducted a literature review in order to investigate the heart rate variability ... -
Chronic Obstructive Pulmonary Disease Mortality in Diesel-Exposed Railroad Workers
(National Institute of Environmental Health Sciences, 2006)Diesel exhaust is a mixture of combustion gases and ultrafine particles coated with organic compounds. There is concern whether exposure can result in or worsen obstructive airway diseases, but there is only limited ... -
The Chthonomonas calidirosea Genome Is Highly Conserved across Geographic Locations and Distinct Chemical and Microbial Environments in New Zealand's Taupō Volcanic Zone
(American Society for Microbiology, 2016)ABSTRACT Chthonomonas calidirosea T49T is a low-abundance, carbohydrate-scavenging, and thermophilic soil bacterium with a seemingly disorganized genome. We hypothesized that the C. calidirosea genome would be highly ... -
Cigarette nicotine yields and nicotine intake among Japanese male workers
(2002)Objectives: To analyse brand nicotine yield including "ultra low" brands (that is, cigarettes yielding less than or equal to 0.1 mg of nicotine by Federal Trade Commission (FTC) methods) in relation to nicotine intake ... -
Cigarette smoking and the risk of diabetes in women.
(American Public Health Association, 1993)Objectives. Noninsulin-dependent diabetes mellitus, a major risk factor for cardiovascular disease, is prevalent in more than 12 million Americans. A voluminous amount of data demonstrates that cigarette smoking is an ... -
Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer
(National Academy of Sciences, 2011)Cigarette smoking has been a well-established risk factor of lung cancer for decades. How smoking contributes to tumorigenesis in the lung remains not fully understood. Here we report the results of a genome-wide study of ... -
Cigarettes and suicide: a prospective study of 50,000 men.
(American Public Health Association, 2000)Objectives. This study examined the relation between smoking and suicide, controlling for various confounders.Methods. More than 50 000 predominantly White. middle-aged and elderly male health professionals were followed ... -
Circadian clock genes and risk of fatal prostate cancer
(Springer (part of Springer Nature), 2015)Circadian genes may be involved in regulating cancer-related pathways, including cell proliferation, DNA damage response, and apoptosis. We aimed to assess the role of genetic variation in core circadian rhythm genes with ... -
Circulating 25-Hydroxyvitamin D and Risk of Non-Hodgkin Lymphoma
(Oxford University Press, 2010)Case-control studies generally suggesting an inverse association between sun exposure and non-Hodgkin lymphoma (NHL) have led to speculation that vitamin D may protect against lymphomagenesis. To examine this hypothesis, ... -
Circulating adiponectin and cardiovascular mortality in patients with type 2 diabetes mellitus: evidence of sexual dimorphism
(BioMed Central, 2014)Background: The pathogenesis of cardiovascular (CV) mortality, whose rate is increased in type 2 diabetes, is poorly understood. While high serum adiponectin is associated with increased CV mortality in the general population, ... -
Circulating and Dietary Omega‐3 and Omega‐6 Polyunsaturated Fatty Acids and Incidence of CVD in the Multi‐Ethnic Study of Atherosclerosis
(Blackwell Publishing Ltd, 2013)Background: Dietary guidelines support intake of polyunsaturated fatty acids (PUFAs) in fish and vegetable oils. However, some controversy remains about benefits of PUFAs, and most prior studies have relied on self‐reported ... -
Circulating and dietary α-linolenic acid and incidence of congestive heart failure in older adults: the Cardiovascular Health Study
(Oxford University Press, 2012) -
Circulating Angiogenic Factors and the Risk of Adverse Outcomes among Haitian Women with Preeclampsia
(Public Library of Science, 2015)Objective: Angiogenic factors are strongly associated with adverse maternal and fetal outcomes among women with preterm preeclampsia (PE) in developed countries. We evaluated the role of angiogenic factors and their ...