Browsing SPH Scholarly Articles by Title

Now showing items 2321-2340 of 6362

    • Fast and accurate long-range phasing in a UK Biobank cohort 

      Loh, Po-Ru; Palamara, Pier Francesco; Price, Alkes L (2016)
      Recent work has leveraged the extensive genotyping of the Icelandic population to perform long-range phasing (LRP), enabling accurate imputation and association analysis of rare variants in target samples typed on genotyping ...

    • Fat intake after diagnosis and risk of lethal prostate cancer and all-cause mortality 

      Richman, Erin L.; Kenfield, Stacey A.; Chavarro, Jorge E.; Stampfer, Meir; Giovannucci, Edward L.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Chan, June M. (American Medical Association, 2013)
      IMPORTANCE Nearly 2.5 million men currently live with prostate cancer in the United States, yet little is known about the association between diet after diagnosis and prostate cancer progression and overall mortality.OBJECTIVE ...

    • Fat intake after prostate cancer diagnosis and mortality in the Physicians’ Health Study 

      Van Blarigan, Erin L.; Kenfield, Stacey; Yang, Meng; Sesso, Howard; Ma, Jing; Stampfer, Meir; Chan, June; Chavarro, Jorge (Springer (part of Springer Nature), 2015)
      Diet after prostate cancer diagnosis may impact disease progression. We hypothesized that consuming saturated fat after prostate cancer diagnosis would increase risk of mortality, and consuming vegetable fat after diagnosis ...

    • Fat Mass–and Obesity-Associated (FTO) Gene Variant Is Associated With Obesity 

      Qi, Lu; Kang, Kihwa; Zhang, Cuilin; van Dam, Rob M.; Kraft, Peter; Hunter, David; Lee, Chih-Hao; Hu, Frank B. (American Diabetes Association, 2008)
      OBJECTIVE—To examine the longitudinal association of fat mass–and obesity-associated (FTO) variant with obesity, circulating adipokine levels, and FTO expression in various materials from human and mouse. RESEARCH DESIGN ...

    • Fat, Protein, and Meat Consumption and Renal Cell Cancer Risk: A Pooled Analysis of 13 Prospective Studies 

      Lee, Jung Eun; Spiegelman, Donna; Hunter, David J.; Albanes, Demetrius; Bernstein, Leslie; Brandt, Piet den; Buring, Julie E.; Cho, Eunyoung; English, Dallas R.; Freudenheim, Jo L.; Giles, Graham G.; Graham, Saxon; Horn-Ross, Pamela L.; Håkansson, Niclas; Leitzmann, Michael F.; Männistö, Satu; McCullough, Marjorie L.; Miller, Anthony B.; Parker, Alexander S.; Rohan, Thomas E.; Schatzkin, Arthur; Schouten, Leo J.; Sweeney, Carol; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Wolk, Alicja; Zhang, Shumin M.; Smith-Warner, Stephanie A. (Oxford University Press, 2008)
      Results of several case-control studies suggest that high consumption of meat (all meat, red meat, or processed meat) is associated with an increased risk of renal cell cancer, but only a few prospective studies have ...

    • Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection 

      Hochman, Sarah E.; Madaline, Theresa F.; Wassmer, Samuel C.; Mbale, Emmie; Choi, Namjong; Seydel, Karl B.; Whitten, Richard O.; Varughese, Julie; Grau, Georges E. R.; Kamiza, Steve; Molyneux, Malcolm E.; Taylor, Terrie E.; Lee, Sunhee; Milner, Danny A.; Kim, Kami (American Society of Microbiology, 2015)
      ABSTRACT Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation ...

    • Fatal Stroke after the Death of a Sibling: A Nationwide Follow-Up Study from Sweden 

      Rostila, Mikael; Saarela, Jan; Kawachi, Ichiro (Public Library of Science, 2013)
      Background: Although less studied than other types of familial losses, the loss of a sibling could be a potential trigger of stroke as it represents a stressful life event. We studied the association between loss of a ...

    • The Fate of Madagascar’s Rainforest Habitat 

      Morelli, Toni Lyn; Smith, Adam B.; Mancini, Amanda N.; Balko, Elizabeth A.; Borgerson, Cortni; Dolch, Rainer; Farris, Zachary; Federman, Sarah; Golden, Christopher; Holmes, Sheila M.; Irwin, Mitchell; Jacobs, Rachel L.; Johnson, Steig; King, Tony; Lehman, Shawn M.; Louis, Edward E.; Murphy, Asia; Randriahaingo, Hery N. T.; Randrianarimanana, H. L. Lucien; Ratsimbazafy, Jonah; Razafindratsima, Onja H.; Baden, Andrea L. (Springer Science and Business Media LLC, 2019-12-23)
      Madagascar has experienced extensive deforestation and overharvesting, and anthropogenic climate change will compound these pressures. Anticipating these threats to endangered species and their ecosystems requires considering ...

    • Fatigue and Depression in Sick-Listed Chronic Low Back Pain Patients 

      Snekkevik, Hildegun; Eriksen, Hege R; Tangen, Tone; Chalder, Trudie; Reme, Silje E (BlackWell Publishing Ltd, 2014)
      Objective: The relationship between fatigue and pain has been investigated previously, but little is known about the prevalence of substantial fatigue in patients sick-listed for chronic low back pain (CLBP) and about how ...

    • Fatty Acid Binding Protein 4 Deficiency Protects against Oxygen-Induced Retinopathy in Mice 

      Saint-Geniez, Magali; Ghelfi, Elisa; Liang, Xiaoliang; Yu, Chenwei; Spencer, Carrie; Abend, Stephanie; Hotamisligil, Gokhan; Cataltepe, Sule (Public Library of Science, 2014)
      Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide due to increasing survival rates of premature infants. Initial suppression, followed by increased production of the retinal vascular ...

    • Fatty Acid Desaturase Gene Variants, Cardiovascular Risk Factors, and Myocardial Infarction in the Costa Rica Study 

      Aslibekyan, S.; Jensen, Majken Karoline; Campos, Hannia; Linkletter, C. D.; Loucks, E. B.; Ordovas, J. M.; Deka, R.; Rimm, Eric B.; Baylin, A. (Frontiers Research Foundation, 2012)
      Genetic variation in fatty acid desaturases (FADS) has previously been linked to long-chain polyunsaturated fatty acids (PUFAs) in adipose tissue and cardiovascular risk. The goal of our study was to test associations ...

    • Fatty Acid Synthase Polymorphisms, Tumor Expression, Body Mass Index, Prostate Cancer Risk, and Survival 

      Nguyen, Paul L.; Ma, Jing; Chavarro, Jorge E.; Freedman, Matthew L.; Lis, Rosina; Fedele, Giuseppe; Fiore, Christopher; Qiu, Weiliang; Fiorentino, Michelangelo; Finn, Stephen; Penney, Kathryn L.; Eisenstein, Anna; Schumacher, Fredrick R.; Mucci, Lorelei A.; Stampfer, Meir; Giovannucci, Edward; Loda, Massimo (American Society of Clinical Oncology, 2010)
      Purpose: Fatty acid synthase (FASN) regulates de novo lipogenesis, body weight, and tumor growth. We examined whether common germline single nucleotide polymorphisms (SNPs) in the FASN gene affect prostate cancer (PCa) ...

    • Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer 

      Migita, Toshiro; Ruiz, Stacey; Fornari, Alessandro; Fiorentino, Michelangelo; Priolo, Carmen; Zadra, Giorgia; Inazuka, Fumika; Grisanzio, Chiara; Palescandolo, Emanuele; Shin, Eyoung; Fiore, Christopher; Xie, Wanling; Kung, Andrew L.; Febbo, Phillip G.; Subramanian, Aravind; Mucci, Lorelei; Ma, Jing; Signoretti, Sabina; Stampfer, Meir; Hahn, William C.; Finn, Stephen; Loda, Massimo (Oxford University Press, 2009)
      Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN.We used immortalized human prostate epithelial cells (iPrECs), ...

    • Fatty acids in the de novo lipogenesis pathway and risk of coronary heart disease: the Cardiovascular Health Study 

      Wu, Jason H. Y.; Lemaitre, Rozenn N.; Imamura, Fumiaki; King, Irena B.; Song, Xiaoling; Spiegelman, Donna; Siscovick, David S.; Mozaffarian, Dariush (Oxford University Press, 2011)
      Background: De novo lipogenesis (DNL) is an endogenous pathway whereby carbohydrates and proteins are converted to fatty acids. DNL could affect coronary heart disease (CHD) or sudden cardiac arrest (SCA) via generation ...

    • Feasibility and impact of Creciendo Sanos, a clinic-based pilot intervention to prevent obesity among preschool children in Mexico City 

      Martínez-Andrade, Gloria Oliva; Cespedes, Elizabeth M; Rifas-Shiman, Sheryl L; Romero-Quechol, Guillermina; González-Unzaga, Marco Aurelio; Benítez-Trejo, María Amalia; Flores-Huerta, Samuel; Horan, Chrissy; Haines, Jess; Taveras, Elsie M; Pérez-Cuevas, Ricardo; Gillman, Matthew W (BioMed Central, 2014)
      Background: Mexico has the highest adult overweight and obesity prevalence in the Americas; 23.8% of children <5 years old are at risk for overweight and 9.7% are already overweight or obese. Creciendo Sanos was a pilot ...

    • The Feasibility and Impact of Delivering a Mind-Body Intervention in a Virtual World 

      Linton, Deborah A.; Bello, Heather E.; Senelly, Marco; Milik, Mariola T.; Baim, Margaret A.; Hoch, Daniel B.; Watson, Alice Joan; Jethwani, Kamal Shanker; Fricchione, Gregory Lewis; Benson, Herbert; Kvedar, Joseph Charles (Public Library of Science, 2012)
      Introduction: Mind-body medical approaches may ameliorate chronic disease. Stress reduction is particularly helpful, but face-to-face delivery systems cannot reach all those who might benefit. An online, 3-dimensional ...

    • Feasibility of a large cohort study in sub-Saharan Africa assessed through a four-country study 

      Dalal, Shona; Holmes, Michelle D.; Laurence, Carien; Bajunirwe, Francis; Guwatudde, David; Njelekela, Marina; Adebamowo, Clement; Nankya-Mutyoba, Joan; Chiwanga, Faraja S.; Volmink, Jimmy; Ajayi, Ikeoluwapo; Kalyesubula, Robert; Reid, Todd G.; Dockery, Douglas; Hemenway, David; Adami, Hans-Olov (Co-Action Publishing, 2015)
      Background: Large prospective epidemiologic studies are vital in determining disease etiology and forming national health policy. Yet, such studies do not exist in sub-Saharan Africa (SSA) notwithstanding the growing burden ...

    • Feasibility of Distributing Rapid Diagnostic Tests for Malaria in the Retail Sector: Evidence from an Implementation Study in Uganda 

      Cohen, Jessica; Fink, Günther; Berg, Katrina; Aber, Flavia; Jordan, Matthew; Maloney, Kathleen; Dickens, William (Public Library of Science, 2012)
      Background: Despite the benefits of malaria diagnosis, most presumed malaria episodes are never tested. A primary reason is the absence of diagnostic tests in retail establishments, where many patients seek care. Malaria ...

    • Feasibility of High-Throughput Genome-Wide Genotyping using DNA from Stored Buccal Cell Samples 

      Loomis, Stephanie J.; Olson, Lana M.; Mirel, Daniel; Crenshaw, Andrew; Rahhal, Brandon; Tetreault, Stephanie; Kraft, Peter; Haines, Jonathan L.; Pasquale, Louis; Wiggs, Janey Lee; Parkin, Melissa; Tworoger, Shelley Slate; Kang, Jae Hee Hee (Libertas Academica, 2010)
      It is unclear if buccal cell samples contain sufficient human DNA with adequately sized fragments for high throughput genetic bioassays. Yet buccal cell sample collection is an attractive alternative to gathering blood ...

    • Feasibility of Using a Web-Based Nutrition Intervention Among Residents of Multiethnic Working-Class Neighborhoods 

      McNeill, Lorna H; Bennett, Gary G.; Viswanath, Kasisomayajula; Emmons, Karen Maria; Puleo, Elaine (Centers for Disease Control and Prevention, 2007)
      Introduction: Using the Internet to promote behavior change is becoming more desirable as Internet use continues to increase among diverse audiences. Yet we know very little about whether this medium is useful or about ...