Browsing SPH Scholarly Articles by Title
Now showing items 3264-3283 of 6362
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Indoor Tanning and Non-Melanoma Skin Cancer: Systematic Review and Meta-Analysis
(BMJ Publishing Group Ltd., 2012)Objective: To synthesise the literature on indoor tanning and non-melanoma skin cancer. Design: Systematic review and meta-analysis. Data sources: PubMed (1966 to present), Embase (1974 to present), and Web of Science (1898 ... -
Induction of IL-17A Precedes Development of Airway Hyperresponsiveness during Diet-Induced Obesity and Correlates with Complement Factor D
(Frontiers Media S.A., 2014)Obesity is a risk factor for the development of asthma. Obese mice exhibit innate airway hyperresponsiveness (AHR), a characteristic feature of asthma, and IL-17A is required for development of AHR in obese mice. The purpose ... -
Industry-sponsored clinical research outside high-income countries: an empirical analysis of registered clinical trials from 2006 to 2013
(BioMed Central, 2015)Background: Industry-sponsored clinical trials, in the past performed almost exclusively in more developed countries, now often recruit participants globally. However, recruitment from outside high-income countries may not ... -
Inefficient Cytotoxic T Lymphocyte–Mediated Killing of HIV-1–Infected Cells In Vivo
(Public Library of Science, 2006)Understanding the role of cytotoxic T lymphocytes (CTLs) in controlling HIV-1 infection is vital for vaccine design. However, it is difficult to assess the importance of CTLs in natural infection. Different human leukocyte ... -
Inequalities in health: definitions, concepts, and theories
(Co-Action Publishing, 2015)Individuals from different backgrounds, social groups, and countries enjoy different levels of health. This article defines and distinguishes between unavoidable health inequalities and unjust and preventable health ... -
Inequalities in utilization of maternal and child health services in Ethiopia: the role of primary health care
(BioMed Central, 2016)Background: Health systems aim to narrow inequality in access to health care across socioeconomic groups and area of residency. However, in low-income countries, studies are lacking that systematically monitor and evaluate ... -
Infant Infections and Respiratory Symptoms in Relation to in Utero Arsenic Exposure in a U.S. Cohort
(National Institute of Environmental Health Sciences, 2015)Background: Arsenic has been linked to disrupted immune function and greater infection susceptibility in highly exposed populations. Well arsenic levels above the U.S. EPA limit occur in our U.S. study area and are of ... -
Infants’ experience-dependent processing of male and female faces: Insights from eye tracking and event-related potentials
(Elsevier BV, 2014)The goal of the present study was to investigate infants' processing of female and male faces. We used an event-related potential (ERP) priming task, as well as a visual-paired comparison (VPC) eye tracking task to explore ... -
Infants’ neural responses to facial emotion in the prefrontal cortex are correlated with temperament: a functional near-infrared spectroscopy study
(Frontiers Media S.A., 2015)Accurate decoding of facial expressions is critical for human communication, particularly during infancy, before formal language has developed. Different facial emotions elicit distinct neural responses within the first ... -
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria
(Nature Publishing Group, 2016)Malaria remains one of the greatest public health challenges worldwide, particularly in sub-Saharan Africa. The clinical outcome of individuals infected with Plasmodium falciparum parasites depends on many factors including ... -
Infectious Disease in a Warming World: How Weather Influenced West Nile Virus in the United States (2001–2005)
(National Institute of Environmental Health Sciences, 2009)Background: The effects of weather on West Nile virus (WNV) mosquito populations in the United States have been widely reported, but few studies assess their overall impact on transmission to humans. Objectives: We ... -
Infective endocarditis and cancer in the elderly
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Inference for the Proportional Hazards Model with Misclassified Discrete-Valued Covariates
(Wiley, 2004)We consider the Cox proportional hazards model with discrete-valued covariates subject to misclassification. We present a simple estimator of the regression parameter vector for this model. The estimator is based on a ... -
Inference of seasonal and pandemic influenza transmission dynamics
(Proceedings of the National Academy of Sciences, 2015)The inference of key infectious disease epidemiological parameters is critical for characterizing disease spread and devising prevention and containment measures. The recent emergence of surveillance records mined from big ... -
Inference of transcriptional regulation in cancers
(Proceedings of the National Academy of Sciences, 2015)We developed an efficient and accurate computational framework, RABIT (regression analysis with background integration), and comprehensively integrated public transcription factor (TF)-binding profiles with TCGA tumor-profiling ... -
Inferring Developmental Stage Composition from Gene Expression in Human Malaria
(Public Library of Science, 2013)In the current era of malaria eradication, reducing transmission is critical. Assessment of transmissibility requires tools that can accurately identify the various developmental stages of the malaria parasite, particularly ... -
Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays
(Public Library of Science, 2006)Loss of heterozygosity (LOH) of chromosomal regions bearing tumor suppressors is a key event in the evolution of epithelial and mesenchymal tumors. Identification of these regions usually relies on genotyping tumor and ... -
Inferring steady state single-cell gene expression distributions from analysis of mesoscopic samples
(BioMed Central, 2006)Background: A great deal of interest has been generated by systems biology approaches that attempt to develop quantitative, predictive models of cellular processes. However, the starting point for all cellular gene ... -
Inflammation and Immune-Related Candidate Gene Associations with Acute Lung Injury Susceptibility and Severity: A Validation Study
(Public Library of Science, 2012)Introduction: Common variants in genes related to inflammation, innate immunity, epithelial cell function, and angiogenesis have been reported to be associated with risks for Acute Lung Injury (ALI) and related outcomes. ... -
Inflammation, the Metabolic Syndrome, and Risk of Coronary Heart Disease in Women and Men
(Elsevier, 2008)Objective: This study examined whether inflammation adds to the prediction of coronary heart disease (CHD) beyond metabolic syndrome (MetS), and whether these associations differ between sexes. Methods and results: Among ...