Now showing items 331-350 of 6362

    • Analyzing historical trends in breast cancer biomarker expression: a feasibility study (1947–2009) 

      Krieger, Nancy; Habel, Laurel A; Waterman, Pamela D; Shabani, Melina; Ellison-Loschmann, Lis; Achacoso, Ninah S; Acton, Luana; Schnitt, Stuart J (2016)
      BACKGROUND/OBJECTIVES Determining long-term trends in tumor biomarker expression is essential for understanding aspects of tumor biology amenable to change. Limiting the availability of such data, currently used assays for ...
    • Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD 

      Chu, Jen-hwa; Hersh, Craig P; Castaldi, Peter J; Cho, Michael H; Raby, Benjamin A; Laird, Nan; Bowler, Russell; Rennard, Stephen; Loscalzo, Joseph; Quackenbush, John; Silverman, Edwin K (BioMed Central, 2014)
      Background: The investigation of complex disease heterogeneity has been challenging. Here, we introduce a network-based approach, using partial correlations, that analyzes the relationships among multiple disease-related ...
    • Anatomy of an Ambush: Security Risks Facing International Humanitarian Assistance 

      Burkle, Frederick (Wiley, 2005)
      The 2003 war with Iraq has generated security concerns that present unique challenges to the practice of providing international humanitarian assistance during war and conflict. Objective research studies on security ...
    • Anatomy of Health Effects of Mediterranean Diet: Greek EPIC Prospective Cohort Study 

      Trichopoulou, Antonia; Bamia, Christina; Trichopoulos, Dimitrios (BMJ Publishing Group, 2009)
      Objective: To investigate the relative importance of the individual components of the Mediterranean diet in generating the inverse association of increased adherence to this diet and overall mortality. Design: Prospective ...
    • Ancient human genomes suggest three ancestral populations for present-day Europeans 

      Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; Kirsanow, Karola; Sudmant, Peter H.; Schraiber, Joshua G.; Castellano, Sergi; Lipson, Mark; Berger, Bonnie; Economou, Christos; Bollongino, Ruth; Fu, Qiaomei; Bos, Kirsten I.; Nordenfelt, Susanne; Li, Heng; de Filippo, Cesare; Prüfer, Kay; Sawyer, Susanna; Posth, Cosimo; Haak, Wolfgang; Hallgren, Fredrik; Fornander, Elin; Rohland, Nadin; Delsate, Dominique; Francken, Michael; Guinet, Jean-Michel; Wahl, Joachim; Ayodo, George; Babiker, Hamza A.; Bailliet, Graciela; Balanovska, Elena; Balanovsky, Oleg; Barrantes, Ramiro; Bedoya, Gabriel; Ben-Ami, Haim; Bene, Judit; Berrada, Fouad; Bravi, Claudio M.; Brisighelli, Francesca; Busby, George B. J.; Cali, Francesco; Churnosov, Mikhail; Cole, David E. C.; Corach, Daniel; Damba, Larissa; van Driem, George; Dryomov, Stanislav; Dugoujon, Jean-Michel; Fedorova, Sardana A.; Romero, Irene Gallego; Gubina, Marina; Hammer, Michael; Henn, Brenna M.; Hervig, Tor; Hodoglugil, Ugur; Jha, Aashish R.; Karachanak-Yankova, Sena; Khusainova, Rita; Khusnutdinova, Elza; Kittles, Rick; Kivisild, Toomas; Klitz, William; Kučinskas, Vaidutis; Kushniarevich, Alena; Laredj, Leila; Litvinov, Sergey; Loukidis, Theologos; Mahley, Robert W.; Melegh, Béla; Metspalu, Ene; Molina, Julio; Mountain, Joanna; Näkkäläjärvi, Klemetti; Nesheva, Desislava; Nyambo, Thomas; Osipova, Ludmila; Parik, Jüri; Platonov, Fedor; Posukh, Olga; Romano, Valentino; Rothhammer, Francisco; Rudan, Igor; Ruizbakiev, Ruslan; Sahakyan, Hovhannes; Sajantila, Antti; Salas, Antonio; Starikovskaya, Elena B.; Tarekegn, Ayele; Toncheva, Draga; Turdikulova, Shahlo; Uktveryte, Ingrida; Utevska, Olga; Vasquez, René; Villena, Mercedes; Voevoda, Mikhail; Winkler, Cheryl; Yepiskoposyan, Levon; Zalloua, Pierre; Zemunik, Tatijana; Cooper, Alan; Capelli, Cristian; Thomas, Mark G.; Ruiz-Linares, Andres; Tishkoff, Sarah A.; Singh, Lalji; Thangaraj, Kumarasamy; Villems, Richard; Comas, David; Sukernik, Rem; Metspalu, Mait; Meyer, Matthias; Eichler, Evan E.; Burger, Joachim; Slatkin, Montgomery; Pääbo, Svante; Kelso, Janet; Reich, David; Krause, Johannes (2014)
      We sequenced the genomes of a ~7,000 year old farmer from Germany and eight ~8,000 year old hunter-gatherers from Luxembourg and Sweden. We analyzed these and other ancient genomes1–4 with 2,345 contemporary humans to show ...
    • Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite 

      Dankwa, Selasi; Lim, Caeul; Bei, Amy K.; Jiang, Rays H. Y.; Abshire, James R.; Patel, Saurabh D.; Goldberg, Jonathan M.; Moreno, Yovany; Kono, Maya; Niles, Jacquin C.; Duraisingh, Manoj T. (Nature Publishing Group, 2016)
      Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell (RBC) surface receptors, many of which are sialylated. While ...
    • Androgen Receptor Cag Repeat Polymorphism and Risk of Tmprss2:erg Positive Prostate Cancer 

      Yoo, Sun; Pettersson, Andreas; Jordahl, Kristina; Lis, Rosina; Lindstrom, Sara; Meisner, Allison; Nuttall, Elizabeth; Stack, Edward; Stampfer, Meir; Kraft, Peter; Brown, Myles; Loda, Massimo; Giovannucci, Edward; Kantoff, Philip; Mucci, Lorelei (American Association for Cancer Research, 2014)
      Background: The androgen receptor (AR) is an essential gene in prostate cancer pathogenesis and progression. Genetic variation in AR exists, including a polymorphic CAG repeat sequence that is inversely associated with ...
    • Anemia and Growth Failure Among HIV-Infected Children in India: a Retrospective Analysis 

      Shet, Anita; Mehta, Saurabh; Rajagopalan, Nirmala; Dinakar, Chitra; Ramesh, Elango; Samuel, NM; Indumathi, CK; Fawzi, Wafaie W.; Kurpad, Anura V (BioMed Central, 2009)
      Background: Anemia and poor nutrition have been previously described as independent risk factors for death among HIV-infected children. We sought to describe nutritional status, anemia burden and HIV disease correlates ...
    • Anemia at the Initiation of Tuberculosis Therapy Is Associated with Delayed Sputum Conversion among Pulmonary Tuberculosis Patients in Dar-es-Salaam, Tanzania 

      Nagu, Tumaini J.; Spiegelman, Donna; Hertzmark, Ellen; Aboud, Said; Makani, Julie; Matee, Mecky I.; Fawzi, Wafaie; Mugusi, Ferdinand (Public Library of Science, 2014)
      Background: Pulmonary tuberculosis and anemia are both prevalent in Tanzania. There is limited and inconsistent literature on the association between anemia and sputum conversion following tuberculosis treatment. Methods: ...
    • Anemia Etiology in Ethiopia: Assessment of Nutritional, Infectious Disease, and Other Risk Factors in a Population-based Cross-sectional Survey of Women, Men, and Children 

      Andersen, Christopher; Tadesse, Amare; Bromage, Sabri; Fekadu, Habtamu; Hemler, Elena; Passarelli, Simone; Spiegelman, Donna; Sudfeld, Christopher; Worku, Alemayehu; Berhane, Yemane; Fawzi, Wafaie (Oxford University Press (OUP), 2021-10-14)
      Background: While the causes of anemia at an individual level (such as certain nutritional deficiencies, infections, and genetic disorders) are well defined, there is limited understanding of the relative burden of anemia ...
    • Anemia of Inflammation Is Related to Cognitive Impairment among Children in Leyte, The Philippines 

      Olson, Courtney L.; Acosta, Luz P.; Hochberg, Natasha S.; Olveda, Remigio M.; Jiz, Mario; McGarvey, Stephen T.; Kurtis, Jonathan D.; Bellinger, David C.; Friedman, Jennifer (Public Library of Science, 2009)
      Background: Many studies have addressed the relationship between iron deficiency anemia (IDA) and cognitive impairment, but none have evaluated the role of non-iron deficiency anemia (NIDA). One of the main causes of NIDA ...
    • Anger Expression and Risk of Stroke and Coronary Heart Disease Among Male Health Professionals 

      Eng, Patricia Mona; Fitzmaurice, Garrett; Kubzansky, Laura D.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Kawachi, Ichiro (2003)
      Objective: Anger expression is a dimension of anger that may be strongly related to coronary heart disease and stroke. To date few cohort studies have evaluated the role of anger coping style in the development of ...
    • Angiogenic and inflammatory biomarkers in midpregnancy and small-for-gestational-age outcomes in Tanzania 

      Darling, Anne Marie; McDonald, Chloe; Conroy, Andrea L.; Hayford, Kyla T.; Liles, W. Conrad; Wang, Molin; Aboud, Said; Urassa, Willy S.; Kain, Kevin C.; Fawzi, Wafaie W. (Elsevier BV, 2014)
      OBJECTIVE To investigate the relationship between a panel of angiogenic and inflammatory biomarkers measured in mid-pregnancy and small-for-gestational age (SGA) outcomes in sub-Saharan Africa. STUDY DESIGN Concentrations ...
    • Angiogenic mRNA and microRNA Gene Expression Signature Predicts a Novel Subtype of Serous Ovarian Cancer 

      Risch, Thomas; Fan, Jian-Bing; Holton, Kristina; Rubio, Renee; April, Craig; Wickham-Garcia, Eliza; Bentink, Stefan; Haibe-Kains, Benjamin; Hirsch, Michelle S.; Chen, Jing; Liu, Joyce; Culhane, Aedin; Drapkin, Ronny I.; Quackenbush, John; Matulonis, Ursula Anne (Public Library of Science, 2012)
      Ovarian cancer is the fifth leading cause of cancer death for women in the U.S. and the seventh most fatal worldwide. Although ovarian cancer is notable for its initial sensitivity to platinum-based therapies, the vast ...
    • Angiogenic Proteins, Placental Weight and Perinatal Outcomes Among Pregnant Women in Tanzania 

      McDonald, Chloe; Darling, Anne Marie; Liu, Enju; Tran, Vanessa; Cabrera, Ana; Aboud, Said; Urassa, Willy; Kain, Kevin C.; Fawzi, Wafaie W. (Public Library of Science (PLoS), 2016)
      Introduction Placental vascular development, and ultimately placental weight, is essential to healthy fetal development. Here, we examined placental weight in a cohort of Tanzanian women in association with angiogenic ...
    • Annotation Enrichment Analysis: An Alternative Method for Evaluating the Functional Properties of Gene Sets 

      Glass, Kimberly; Girvan, Michelle (Nature Publishing Group, 2014)
      Gene annotation databases (compendiums maintained by the scientific community that describe the biological functions performed by individual genes) are commonly used to evaluate the functional properties of experimentally ...
    • Annual Ambient Black Carbon Associated with Shorter Telomeres in Elderly Men: Veterans Affairs Normative Aging Study 

      Hoxha, Mirjam; Dioni, Laura; McCracken, John Patrick; Baccarelli, Andrea; Melly, Steven John; Coull, Brent Andrew; Suh MacIntosh, Helen H.; Vokonas, Pantel S; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2010)
      Background: Telomere length reflects biological age and is inversely associated with risk of cardiovascular disease (CVD). Ambient air pollution is associated with CVD, but its effect on telomere length is unknown. Objective: ...
    • Ante natal care (ANC) utilization, dietary practices and nutritional outcomes in pregnant and recently delivered women in urban slums of Delhi, India: an exploratory cross-sectional study 

      Ghosh-Jerath, Suparna; Devasenapathy, Niveditha; Singh, Archna; Shankar, Anuraj; Zodpey, Sanjay (BioMed Central, 2015)
      Background: Antenatal Care (ANC) is one of the crucial factors in ensuring healthy outcomes in women and newborns. Nutrition education and counselling is an integral part of ANC that influences maternal and child health ...
    • Antenatal and postnatal care: a review of innovative models for improving availability, accessibility, acceptability and quality of services in low‐resource settings 

      Kearns, Annie; Caglia, Jacquelyn M.; ten Hoope-Bender, Petra; Langer, Ana (Wiley, 2015-12-23)
      Key lessons can be drawn from innovative approaches that have been implemented to ensure access to better antenatal care (ANC) and postnatal care (PNC). This paper examines the successes and challenges of ANC and PNC ...
    • Anthropometric Differences between HIV-Infected Individuals Prior to Antiretroviral Treatment and the General Population from 1998–2007: The AIDS Clinical Trials Group Longitudinal Linked Randomized Trials (ALLRT) Cohort and NHANES 

      Atkinson, Benjamin E.; Krishnan, Supriya; Cox, Gary; Hulgan, Todd; Collier, Ann C. (Public Library of Science, 2013)
      Objective: To assess differences in body circumferences and body mass index (BMI, kg/m2) between antiretroviral treatment (ART) naïve HIV-infected and HIV-uninfected persons. Methods: Waist, arm, and thigh circumferences ...