Browsing SPH Scholarly Articles by Title

Now showing items 3361-3380 of 6362

    • Intakes of fruit, vegetables, and carotenoids and renal cell cancer risk: a pooled analysis of 13 prospective studies 

      Lee, Jung Eun; Männistö, Satu; Spiegelman, Donna; Hunter, David; Bernstein, Leslie; van den Brandt, Piet A.; Buring, Julie; Cho, Eunyoung; English, Dallas; Flood, Andrew; Freudenheim, Jo; Giles, Graham; Giovannucci, Edward; Håkansson, Niclas; Horn-Ross, Pamela; Jacobs, Eric; Leitzmann, Michael; Marshall, James; McCullough, Marjorie; Miller, Anthony; Rohan, Thomas; Ross, Julie; Schatzkin, Arthur; Schouten, Leo; Virtamo, Jarmo; Wolk, Alicja; Zhang, Shumin; Smith-Warner, Stephanie (American Association for Cancer Research, 2009)
      Fruit and vegetable consumption has been hypothesized to reduce the risk of renal cell cancer. We conducted a pooled analysis of 13 prospective studies, including 1,478 incident cases of renal cell cancer (709 women and ...

    • Intakes of fruits, vegetables and carbohydrate and the risk of CVD 

      Joshipura, Kaumudi J.; Hung, Hsin-Chia; Li, Tricia Y.; Hu, Frank B.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Stampfer, Meir; Colditz, Graham; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600 (Cambridge University Press, 2009)
      Background: Low-carbohydrate diets could lead to reduced fruit and vegetable intake, which may Ire protective against CVD. The role of carbohydrate intake in modifying the association between fruits and vegetables and CVD ...

    • Intakes of fruits, vegetables and carbohydrate and the risk of CVD 

      Joshipura, Kaumudi J.; Hung, Hsin-Chia; Li, Tricia Y.; Hu, Frank B.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Stampfer, Meir; Colditz, Graham; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600 (2009)
      Background: Low-carbohydrate diets could lead to reduced fruit and vegetable intake, which may Ire protective against CVD. The role of carbohydrate intake in modifying the association between fruits and vegetables and CVD ...

    • Intakes of Fruits, Vegetables, Vitamins A, C, and E, and Carotenoids and Risk of Renal Cell Cancer 

      Lee, J. E.; Giovannucci, E.; Smith-Warner, S. A.; Spiegelman, D.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Curhan, G. C. (American Association for Cancer Research, 2006)
      Background: Fruits and vegetables rich in antioxidants have been proposed to reduce the risk of renal cell cancer. However, few prospective studies have examined the intakes of fruits, vegetables, and antioxidant vitamins ...

    • Intakes of vitamins A, C and E and folate and multivitamins and lung cancer: A pooled analysis of 8 prospective studies 

      Cho, Eunyoung; Hunter, David J.; Spiegelman, Donna; Albanes, Demetrius; Beeson, W. Lawrence; van den Brandt, Piet A.; Colditz, Graham A.; Feskanich, Diane; Folsom, Aaron R.; Fraser, Gary E.; Freudenheim, Jo L.; Giovannucci, Edward; Goldbohm, R. Alexandra; Graham, Saxon; Miller, Anthony B.; Rohan, Thomas E.; Sellers, Thomas A.; Virtamo, Jarmo; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Smith-Warner, Stephanie A. (Wiley, 2006)
      Intakes of vitamins A, C and E and folate have been hypothesized to reduce lung cancer risk. We examined these associations in a pooled analysis of the primary data from 8 prospective studies from North America and Europe. ...

    • Intakes of vitamins A, C, and E and use of multiple vitamin supplements and risk of colon cancer: a pooled analysis of prospective cohort studies 

      Park, Yikyung; Spiegelman, Donna; Hunter, David J.; Albanes, Demetrius; Bergkvist, Leif; Buring, Julie E.; Freudenheim, Jo L.; Giovannucci, Edward; Goldbohm, R. Alexandra; Harnack, Lisa; Kato, Ikuko; Krogh, Vittorio; Leitzmann, Michael F.; Limburg, Paul J.; Marshall, James R.; McCullough, Marjorie L.; Miller, Anthony B.; Rohan, Thomas E.; Schatzkin, Arthur; Shore, Roy; Sieri, Sabina; Stampfer, Meir; Virtamo, Jarmo; Weijenberg, Matty; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Wolk, Alicja; Zhang, Shumin M.; Smith-Warner, Stephanie A. (Springer (part of Springer Nature), 2010)
      To evaluate the associations between intakes of vitamins A, C, and E and risk of colon cancer.Using the primary data from 13 cohort studies, we estimated study- and sex-specific relative risks (RR) with Cox proportional ...

    • Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men 

      Jensen, Majken; Koh-Banerjee, Pauline; Hu, Frank; Franz, Mary; Sampson, Laura; Grønbæk, Morten; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600 (Oxford University Press, 2004)
      Background: Previous studies have suggested that a daily intake of 3 servings of whole-grain foods is associated with a reduced risk of coronary heart disease (CHD). However, methods for the assessment of whole-grain intake ...

    • Integrated Bio-Entity Network: A System for Biological Knowledge Discovery 

      Bell, Lindsey; Chowdhary, Rajesh; Liu, Jun; Niu, Xufeng; Zhang, Jinfeng (Public Library of Science (PLoS), 2011)
      A significant part of our biological knowledge is centered on relationships between biological entities (bio-entities) such as proteins, genes, small molecules, pathways, gene ontology (GO) terms and diseases. Accumulated ...

    • Integrated Functional Networks of Process, Tissue, and Developmental Stage Specific Interactions in Arabidopsis thaliana 

      Pop, Ana; Huttenhower, Curtis; Iyer-Pascuzzi, Anjali; Benfey, Philip N; Troyanskaya, Olga G (BioMed Central, 2010)
      Background: Recent years have seen an explosion in plant genomics, as the difficulties inherent in sequencing and functionally analyzing these biologically and economically significant organisms have been overcome. Arabidopsis ...

    • Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis 

      Bunyavanich, Supinda; Schadt, Eric E; Himes, Blanca E; Lasky-Su, Jessica; Qiu, Weiliang; Lazarus, Ross; Ziniti, John P; Cohain, Ariella; Linderman, Michael; Torgerson, Dara G; Eng, Celeste S; Pino-Yanes, Maria; Padhukasahasram, Badri; Yang, James J; Mathias, Rasika A; Beaty, Terri H; Li, Xingnan; Graves, Penelope; Romieu, Isabelle; Navarro, Blanca del Rio; Salam, M Towhid; Vora, Hita; Nicolae, Dan L; Ober, Carole; Martinez, Fernando D; Bleecker, Eugene R; Meyers, Deborah A; Gauderman, W James; Gilliland, Frank; Burchard, Esteban G; Barnes, Kathleen C; Williams, L Keoki; London, Stephanie J; Zhang, Bin; Raby, Benjamin A; Weiss, Scott T (BioMed Central, 2014)
      Background: Allergic rhinitis is a common disease whose genetic basis is incompletely explained. We report an integrated genomic analysis of allergic rhinitis. Methods: We performed genome wide association studies (GWAS) ...

    • Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma 

      Sausen, Mark; Leary, Rebecca J.; Jones, Siân; Wu, Jian; Reynolds, C. Patrick; Liu, Xueyuan; Blackford, Amanda; Parmigiani, Giovanni; Diaz, Luis A.; Papadopoulos, Nickolas; Vogelstein, Bert; Kinzler, Kenneth W.; Velculescu, Victor E.; Hogarty, Michael D. (2012)
      Neuroblastomas are tumors of peripheral sympathetic neurons and are the most common solid tumor in children. To determine the genetic basis for neuroblastoma we performed whole-genome sequencing (6 cases), exome sequencing ...

    • Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium 

      Salomonis, Nathan; Dexheimer, Phillip J.; Omberg, Larsson; Schroll, Robin; Bush, Stacy; Huo, Jeffrey; Schriml, Lynn; Ho Sui, Shannan; Keddache, Mehdi; Mayhew, Christopher; Shanmukhappa, Shiva Kumar; Wells, James; Daily, Kenneth; Hubler, Shane; Wang, Yuliang; Zambidis, Elias; Margolin, Adam; Hide, Winston; Hatzopoulos, Antonis K.; Malik, Punam; Cancelas, Jose A.; Aronow, Bruce J.; Lutzko, Carolyn (Elsevier, 2016)
      Summary The rigorous characterization of distinct induced pluripotent stem cells (iPSC) derived from multiple reprogramming technologies, somatic sources, and donors is required to understand potential sources of variability ...

    • Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia 

      Juraeva, Dilafruz; Haenisch, Britta; Zapatka, Marc; Frank, Josef; Witt, Stephanie H.; Mühleisen, Thomas W.; Treutlein, Jens; Strohmaier, Jana; Meier, Sandra; Degenhardt, Franziska; Giegling, Ina; Ripke, Stephan; Leber, Markus; Lange, Christoph; Schulze, Thomas G.; Mössner, Rainald; Nenadic, Igor; Sauer, Heinrich; Rujescu, Dan; Maier, Wolfgang; Børglum, Anders; Ophoff, Roel; Cichon, Sven; Nöthen, Markus M.; Rietschel, Marcella; Mattheisen, Manuel; Brors, Benedikt (Public Library of Science, 2014)
      In the present study, an integrated hierarchical approach was applied to: (1) identify pathways associated with susceptibility to schizophrenia; (2) detect genes that may be potentially affected in these pathways since ...

    • Integrated Proteomic Analysis of Human Cancer Cells and Plasma from Tumor Bearing Mice for Ovarian Cancer Biomarker Discovery 

      Pitteri, Sharon J.; JeBailey, Lellean; Faça, Vitor M.; Thorpe, Jason D.; Silva, Melissa A.; Ireton, Reneé C.; Horton, Marc B.; Pruitt, Liese C.; Urban, Nicole; Hanash, Samir M.; Nordheim, Alfred; Wang, Hong; Zhang, Qing; Cheng, Yu-Kang; Dinulescu, Daniela M (Public Library of Science, 2009)
      Background: The complexity of the human plasma proteome represents a substantial challenge for biomarker discovery. Proteomic analysis of genetically engineered mouse models of cancer and isolated cancer cells and cell ...

    • An Integrated Risk Function for Estimating the Global Burden of Disease Attributable to Ambient Fine Particulate Matter Exposure 

      Burnett, Richard T.; Pope, C. Arden; Ezzati, Majid; Olives, Casey; Lim, Stephen S.; Mehta, Sumi; Shin, Hwashin H.; Singh, Gitanjali; Hubbell, Bryan; Brauer, Michael; Anderson, H. Ross; Smith, Kirk R.; Balmes, John R.; Bruce, Nigel G.; Kan, Haidong; Laden, Francine; Prüss-Ustün, Annette; Turner, Michelle C.; Gapstur, Susan M.; Diver, W. Ryan; Cohen, Aaron (National Institute of Environmental Health Sciences, 2014)
      Background: Estimating the burden of disease attributable to long-term exposure to fine particulate matter (PM2.5) in ambient air requires knowledge of both the shape and magnitude of the relative risk (RR) function. ...

    • Integrated Spatial Genomics Reveals Global Architecture of Single Nuclei 

      Takei, Yodai; Yun, Jina; Zheng, Shiwei; Ollikainen, Noah; Pierson, Nico; White, Jonathan; Shah, Sheel; Thomassie, Julian; Suo, ShengBao; Eng, Chee-Huat Linus; Guttman, Mitchell; Yuan, Guo-Cheng; Cai, Long (Springer Science and Business Media LLC, 2021-01-27)
      Identifying the relationships between chromosome structures, nuclear bodies, chromatin states, and gene expression is an overarching goal of nuclear organization studies1–4. Because individual cells appear to be highly ...

    • Integrating an infectious disease programme into the primary health care service: a retrospective analysis of Chagas disease community-based surveillance in Honduras 

      Hashimoto, Ken; Zúniga, Concepción; Nakamura, Jiro; Hanada, Kyo (BioMed Central, 2015)
      Background: Integration of disease-specific programmes into the primary health care (PHC) service has been attempted mostly in clinically oriented disease control such as HIV/AIDS and tuberculosis but rarely in vector ...

    • Integrating Diverse Genomic Data Using Gene Sets 

      Tyekucheva, Svitlana; Marchionni, Luigi; Karchin, Rachel; Parmigiani, Giovanni (BioMed Central, 2011)
      We introduce and evaluate data analysis methods to interpret simultaneous measurement of multiple genomic features made on the same biological samples. Our tools use gene sets to provide an interpretable common scale for ...

    • Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies 

      Kichaev, Gleb; Yang, Wen-Yun; Lindstrom, Sara; Hormozdiari, Farhad; Eskin, Eleazar; Price, Alkes L.; Kraft, Peter; Pasaniuc, Bogdan (Public Library of Science, 2014)
      Standard statistical approaches for prioritization of variants for functional testing in fine-mapping studies either use marginal association statistics or estimate posterior probabilities for variants to be causal under ...

    • Integrating Health Care to Meet the Needs of the Mother–Infant Pair: A Call for Papers for Year 3 of the Maternal Health Task Force–PLOS Collection 

      Mitchell, Kate; Wegner, Mary Nell; Langer, Ana (Public Library of Science, 2013)
      The Maternal Health Task Force (MHTF) and PLOS Medicine issue the call for papers for Year 3 of the MHTF-PLOS Collection: Integrating Health Care to Meet the Needs of the Mother–Infant Pair. Please see later in the article ...