Browsing SPH Scholarly Articles by Title

Now showing items 3498-3517 of 6362

    • Joint Effect of Genotypic and Phenotypic Features of Reproductive Factors on Endometrial Cancer Risk 

      Wang, Zhanwei; Risch, Harvey; Lu, Lingeng; Irwin, Melinda L.; Mayne, Susan; Schwartz, Peter; Rutherford, Thomas; De Vivo, Immaculata; Yu, Herbert (Nature Publishing Group, 2015)
      Prolonged estrogen exposure is believed to be the major cause of endometrial cancer. As possible markers of estrogen exposure, various menstrual and reproductive features, e.g., ages at menarche and menopause, are found ...

    • Joint Effect of Multiple Common SNPs Predicts Melanoma Susceptibility 

      Fang, Shenying; Han, Jiali; Zhang, Mingfeng; Wang, Li-e; Wei, Qingyi; Amos, Christopher I.; Lee, Jeffrey E. (Public Library of Science, 2013)
      Single genetic variants discovered so far have been only weakly associated with melanoma. This study aims to use multiple single nucleotide polymorphisms (SNPs) jointly to obtain a larger genetic effect and to improve the ...

    • Joint Effects of Colorectal Cancer Susceptibility Loci, Circulating 25-Hydroxyvitamin D and Risk of Colorectal Cancer 

      Hiraki, Linda T.; Joshi, Amit D.; Ng, Kimmie; Fuchs, Charles S.; Ma, Jing; Hazra, Aditi; Peters, Ulrike; Karlson, Elizabeth W.; Giovannucci, Edward; Kraft, Peter; Chan, Andrew T. (Public Library of Science, 2014)
      Background: Genome wide association studies (GWAS) have identified several SNPs associated with colorectal cancer (CRC) susceptibility. Vitamin D is also inversely associated with CRC risk. Methods: We examined main and ...

    • Joint GWAS Analysis: Comparing similar GWAS at different genomic resolutions identifies novel pathway associations with six complex diseases 

      McGeachie, Michael John; Clemmer, George L.; Lasky-Su, Jessica A. Lasky; Dahlin, Amber Aziza; Raby, Benjamin Alexander; Weiss, Scott Tillman (Elsevier BV, 2014)
      We show here that combining two existing genome wide association studies (GWAS) yields additional biologically relevant information, beyond that obtained by either GWAS separately. We propose Joint GWAS Analysis, a method ...

    • The Joint Impact on Being Overweight of Self Reported Behaviours of Eating Quickly and Eating until Full: Cross Sectional Survey 

      Maruyama, Koutatsu; Sato, Shinichi; Ohira, Tetsuya; Maeda, Kenji; Kubota, Yoshimi; Nishimura, Setsuko; Kitamura, Akihiko; Kiyama, Masahiko; Okada, Takeo; Imano, Hironori; Nakamura, Masakazu; Ishikawa, Yoshinori; Kurokawa, Michinori; Sasaki, Satoshi; Iso, Hiroyasu; Noda, Hiroyuki (BMJ Publishing Group Ltd., 2008)
      Objective: To examine whether eating until full or eating quickly or combinations of these eating behaviours are associated with being overweight. Design and participants: Cross sectional survey. Setting: Two communities ...

    • Kangaroo Mother Care and Neonatal Outcomes: A Meta-analysis 

      Boundy, Ellen; Dastjerdi, Roya; Spiegelman, Donna; Fawzi, Wafaie; Missmer, Stacey; Lieberman, Ellice; Kajeepeta, Sandhya; Wall, Stephen; Chan, Grace (American Academy of Pediatrics, 2016)
      CONTEXT: Kangaroo mother care (KMC) is an intervention aimed at improving outcomes among preterm and low birth weight newborns. Objective: Conduct a systematic review and meta-analysis estimating the association between ...

    • Kangaroo mother care: a systematic review of barriers and enablers 

      Chan, Grace J; Labar, Amy S; Wall, Stephen; Atun, Rifat (World Health Organization, 2016)
      Abstract Objective: To investigate factors influencing the adoption of kangaroo mother care in different contexts. Methods: We searched PubMed, Embase, Scopus, Web of Science and the World Health Organization’s regional ...

    • Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study 

      Chipps, Bradley E.; Zeiger, Robert S.; Borish, Larry; Wenzel, Sally E.; Yegin, Ashley; Hayden, Mary Lou; Miller, Dave P.; Bleecker, Eugene R.; Simons, F. Estelle R.; Szefler, Stanley J.; Weiss, Scott Tillman; Haselkorn, Tmirah (Elsevier BV, 2012)
      Patients with severe or difficult-to-treat asthma are an understudied population but account for considerable asthma morbidity, mortality, and costs. The Epidemiology and Natural History of Asthma: Outcomes and Treatment ...

    • Key Findings on Alcohol Consumption and a Variety of Health Outcomes From the Nurses’ Health Study 

      Mostofsky, Elizabeth; Mukamal, Kenneth; Giovannucci, Ed; Stampfer, Meir; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600 (American Public Health Association, 2016)
      Objectives. To review critical contributions from the Nurses' Health Study (NHS) on alcohol consumption and health outcomes.Methods. We performed a narrative review of NHS (1980-2012) and NHS II (1989-2011) publications.Results. ...

    • Kidney function and risk of cardiovascular disease and mortality in women: a prospective cohort study 

      Kurth, Tobias; de Jong, Paul E; Cook, Nancy Romanowicz; Buring, Julie Elizabeth; Ridker, Paul M. (BMJ Publishing Group Ltd., 2009)
      Objective: To evaluate the association of kidney function with cardiovascular disease and mortality among apparently healthy women. Design: Prospective cohort study. Setting: Women’s Health Study, United States. Participants: ...

    • Killer Cell Immunoglobulin-Like Receptor Alleles Alter HIV Disease in Children 

      Singh, Kumud K.; Qin, Min; Brummel, Sean S.; Angelidou, Konstantia; Trout, Rodney N.; Fenton, Terence; Spector, Stephen A. (Public Library of Science, 2016)
      Background: HLA class I molecules are ligands for killer cell immunoglobin like receptors (KIR) that control the antiviral response of natural killer (NK) cells. However, the effects of KIR and HLA (KIR/HLA) alleles on HIV ...

    • Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy 

      Kuijjer, Marieke L; van den Akker, Brendy EWM; Hilhorst, Riet; Mommersteeg, Monique; Buddingh, Emilie P; Serra, Massimo; Bürger, Horst; Hogendoorn, Pancras CW; Cleton-Jansen, Anne-Marie (BioMed Central, 2014)
      Background: High-grade osteosarcoma is a primary malignant bone tumor mostly occurring in adolescents and young adults, with a second peak at middle age. Overall survival is approximately 60%, and has not significantly ...

    • KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference 

      Schumann, Gunter; Liu, Chunyu; O’Reilly, Paul; Gao, He; Song, Parkyong; Xu, Bing; Ruggeri, Barbara; Amin, Najaf; Jia, Tianye; Preis, Sarah; Lepe, Marcelo Segura; Akira, Shizuo; Barbieri, Caterina; Baumeister, Sebastian; Cauchi, Stephane; Clarke, Toni-Kim; Enroth, Stefan; Fischer, Krista; Hällfors, Jenni; Harris, Sarah; Hieber, Saskia; Hofer, Edith; Hottenga, Jouke-Jan; Åsa Johansson; Joshi, Peter; Kaartinen, Niina; Laitinen, Jaana; Lemaitre, Rozenn; Loukola, Anu; Jian’an Luan; Lyytikäinen, Leo-Pekka; Mangino, Massimo; Manichaikul, Ani; Mbarek, Hamdi; Milaneschi, Yuri; Moayyeri, Alireza; Mukamal, Kenneth; Nelson, Christopher; Nettleton, Jennifer; Partinen, Eemil; Rawal, Rajesh; Robino, Antonietta; Rose, Lynda; Sala, Cinzia; Satoh, Takashi; Schmidt, Reinhold; Schraut, Katharina; Scott, Robert; Smith, Albert Vernon; Starr, John; Teumer, Alexander; Trompet, Stella; Uitterlinden, André G.; Venturini, Cristina; Vergnaud, Anne-Claire; Verweij, Niek; Vitart, Veronique; Vuckovic, Dragana; Wedenoja, Juho; Yengo, Loic; Yu, Bing; Zhang, Weihua; Zhao, Jing Hua; Boomsma, Dorret; Chambers, John; Chasman, Daniel; Daniela, Toniolo; de Geus, Eco; Deary, Ian; Eriksson, Johan; Tõnu Esko; Eulenburg, Volker; Franco, Oscar; Froguel, Philippe; Gieger, Christian; Grabe, Hans; Gudnason, Vilmundur; Gyllensten, Ulf; Harris, Tamara; Hartikainen, Anna-Liisa; Heath, Andrew; Hocking, Lynne; Hofman, Albert; Huth, Cornelia; Jarvelin, Marjo-Riitta; Jukema, J. Wouter; Kaprio, Jaakko; Kooner, Jaspal; Kutalik, Zoltan; Lahti, Jari; Langenberg, Claudia; Lehtimäki, Terho; Liu, Yongmei; Madden, Pamela; Martin, Nicholas; Morrison, Alanna; Penninx, Brenda; Pirastu, Nicola; Psaty, Bruce; Raitakari, Olli (National Academy of Sciences, 2016)

    • Knowledge and perceptions of risk for cardiovascular disease: Findings of a qualitative investigation from a low-income peri-urban community in the Western Cape, South Africa 

      Surka, Sam; Steyn, Krisela; Everett-Murphy, Katherine; Gaziano, Thomas A.; Levitt, Naomi (AOSIS OpenJournals, 2015)
      Background: South Africa currently faces an increasing burden of cardiovascular disease. Although referred to clinics after community screening initiatives, few individuals who are identified to be at high risk for developing ...

    • Knowledge, Beliefs and Practices Regarding Antiretroviral Medications for HIV Prevention: Results from a Survey of Healthcare Providers in New England 

      Krakower, Douglas S.; Oldenburg, Catherine E.; Mitty, Jennifer A.; Wilson, Ira B.; Kurth, Ann E.; Maloney, Kevin M.; Gallagher, Donna; Mayer, Kenneth H. (Public Library of Science, 2015)
      Background: Antiretroviral treatment for HIV-infection before immunologic decline (early ART) and pre-exposure chemoprophylaxis (PrEP) can prevent HIV transmission, but routine adoption of these practices by clinicians has ...

    • Laboratory and Clinical Predictors of Disease Progression following Initiation of Combination Therapy in HIV-Infected Adults in Thailand 

      Duong, Trinh; Jourdain, Gonzague Joseph Albert; Ngo-Giang-Huong, Nicole; Le Cœur, Sophie; Kantipong, Pacharee; Buranabanjasatean, Sudanee; Leenasirimakul, Prattana; Ariyadej, Sriprapar; Tansuphasawasdikul, Somboon; Thongpaen, Suchart; Lallemant, Marc Jean (Public Library of Science, 2012)
      Background: Data on determinants of long-term disease progression in HIV-infected patients on antiretroviral therapy (ART) are limited in low and middle-income settings. Methods: Effects of current CD4 count, viral load ...

    • Laboratory Mouse Models for the Human Genome-Wide Associations 

      Kitsios, Georgios D.; Tangri, Navdeep; Castaldi, Peter J.; Ioannidis, John (Public Library of Science, 2010)
      The agnostic screening performed by genome-wide association studies (GWAS) has uncovered associations for previously unsuspected genes. Knowledge about the functional role of these genes is crucial and laboratory mouse ...

    • Lack of association between dietary protein intake and risk of stroke among middle-aged men 

      Preis, Sarah Rosner; Stampfer, Meir; Spiegelman, Donna; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600 (Oxford University Press, 2010)
      Background: Prospective cohort studies in Japanese populations have shown an inverse association between dietary protein and stroke risk. However, this association has not been examined among any study populations of US ...

    • Lack of dietary diversity and dyslipidaemia among stunted overweight children: the 2002 China National Nutrition and Health Survey 

      Li, Yanping; Wedick, Nicole M.; Lai, Jianqiang; He, Yuna; Hu, Xiaoqi; Liu, Ailing; Du, Songming; Zhang, Jian; Yang, Xiaoguang; Chen, Chunming; Hu, Frank B.; Ma, Guansheng (Cambridge University Press, 2011)
      Objective: Both stunting and overweight are present in children across China. Seemingly paradoxical, these two conditions can also coexist in the same child. The aim was to examine the associations between dietary food/nutrient ...

    • Lack of reproducibility of linkage results in serially measured blood pressure data 

      Patel, Sanjay R; Celedon, Juan C; Weiss, Scott Tillman; Palmer, Lyle J (BioMed Central, 2003)
      Background: Using the longitudinal Framingham Heart Study data on blood pressure, we analyzed the reproducibility of linkage measures from serial cross-sectional surveys of a defined population by performing genome-wide ...