Browsing SPH Scholarly Articles by Title

Now showing items 3710-3729 of 6362

    • A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever 

      Park, Ki Soo; Chung, Hyun Jung; Khanam, Farhana; Lee, Hakho; Rashu, Rasheduzzaman; Bhuiyan, Md. Taufiqur; Berger, Amanda; Harris, Jason B.; Calderwood, Stephen B.; Ryan, Edward T.; Qadri, Firdausi; Weissleder, Ralph; Charles, Richelle C. (Nature Publishing Group, 2016)
      There is currently no widely available optimal assay for diagnosing patients with enteric fever. Here we present a novel assay designed to detect amplified Salmonella nucleic acid (mRNA) using magneto-DNA probes and a ...

    • Magnitude and Frequency of Cytotoxic T-Lymphocyte Responses: Identification of Immunodominant Regions of Human Immunodeficiency Virus Type 1 Subtype C 

      Novitsky, Vladimir A.; Cao, H.; Rybak, N.; Gilbert, P.; McLane, Mary Frances; Gaolekwe, S.; Peter, T.; Thior, I.; Ndung, T.; Marlink, Richard G.; Lee, Tae Ho; Essex, Myron Elmer (American Society for Microbiology, 2002)
      A systematic analysis of immune responses on a population level is critical for a human immunodeficiency virus type 1 (HIV-1) vaccine design. Our studies in Botswana on (i) molecular analysis of the HIV-1 subtype C (HIV-1C) ...

    • Major Copy Proportion Analysis of Tumor Samples Using SNP Arrays 

      Li, Cheng; Beroukhim, Rameen; Weir, Barbara Ann; Winckler, Wendy; Garraway, Levi Alexander; Sellers, William R; Meyerson, Matthew Langer (BioMed Central, 2008)
      Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays have been developed for high-throughput ...

    • Major depressive disorder prevalence and risk factors among Syrian asylum seekers in Greece 

      Poole, Danielle Nicole; Hedt-Gauthier, Bethany Lynn; Liao, Shirley X; Raymond, Nathaniel Adam; Bärnighausen, Till (Springer Nature, 2018)
      Background Over one million Syrian asylum seekers have travelled to Greece with the ultimate aim of reaching other countries in western Europe. Depression prevalence and associated sociodemographic and displacement ...

    • Major Dietary Patterns and Cardiovascular Risk Factors among Young Brazilian Adults 

      Olinto, Maria Teresa A.; Gigante, Denise P.; Horta, Bernardo; Silveira, Vera; Oliveira, Isabel; Willett, Walter C. (Springer-Verlag, 2011)
      Purpose: Diet is one of the most important modifiable risk factors for cardiovascular diseases. The scientific literature has consistently shown the effects of certain diets on health; however, given the variety of cultures ...

    • Major Dietary Patterns in Relation to General and Central Obesity among Chinese Adults 

      Yu, Canqing; Shi, Zumin; Lv, Jun; Du, Huaidong; Qi, Lu; Guo, Yu; Bian, Zheng; Chang, Liang; Tang, Xuefeng; Jiang, Qilian; Mu, Huaiyi; Pan, Dongxia; Chen, Junshi; Chen, Zhengming; Li, Liming (MDPI, 2015)
      Limited evidence exists for the association between diet pattern and obesity phenotypes among Chinese adults. In the present study, we analyzed the cross-sectional data from 474,192 adults aged 30–79 years from the China ...

    • Major Dietary Protein Sources and Risk of Coronary Heart Disease in Women 

      Bernstein, A. M.; Sun, Q.; Hu, F. B.; Stampfer, Meir; Manson, J. E.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600 (American Heart Association, 2010)
      Background-With the exception of fish, few major dietary protein sources have been studied in relation to the development of coronary heart disease (CHD). Our objective was to examine the relation between foods that are ...

    • Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies 

      Jakobsen, Marianne U.; O'Reilly, Eilis J.; Heitmann, Berit L.; Pereira, Mark A.; Bälter, Katarina; Fraser, Gary E.; Goldbourt, Uri; Hallmans, Göran; Knekt, Paul; Liu, Simin; Pietinen, Pirjo; Spiegelman, Donna; Stevens, June; Virtamo, Jarmo; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Ascherio, Alberto (Oxford University Press, 2009)
      Background: Saturated fatty acid (SFA) intake increases plasma LDL-cholesterol concentrations; therefore, intake should be reduced to prevent coronary heart disease (CHD). Lower habitual intakes of SFAs, however, require ...

    • Making Stillbirths Count, Making Numbers Talk - Issues in Data collection for Stillbirths 

      Frøen, J Frederik; Gordijn, Sanne J; Abdel-Aleem, Hany; Bergsjø, Per; Betran, Ana; Duke, Charles W; Fauveau, Vincent; Flenady, Vicki; Hinderaker, Sven Gudmund; Hofmeyr, G Justus; Jokhio, Abdul Hakeem; Lawn, Joy; Lumbiganon, Pisake; Merialdi, Mario; Pattinson, Robert; Shankar, Anuraj H. (BioMed Central, 2009)
      Background: Stillbirths need to count. They constitute the majority of the world's perinatal deaths and yet, they are largely invisible. Simply counting stillbirths is only the first step in analysis and prevention. From ...

    • Making the Case for Better Integration of Cervical Cancer Screening and Treatment for HIV-Infected Women Attending Care and Treatment Clinics in Dar es Salaam, Tanzania 

      McCree-Hale, Renicha; Aris, Eric; Chalamilla, Guerino; Andrew, Irene; Mwaiselage, Julius; Spiegelman, Donna Lynn; Hirschorn, Lisa; Fawzi, Wafaie W. (BioMed Central, 2012)

    • Malaria Control in South Africa 2000–2010: Beyond MDG6 

      Moonasar, Devanand; Nuthulaganti, Tej; Kruger, Philip S; Mabuza, Aaron; Rasiswi, Eric S; Benson, Frew G; Maharaj, Rajendra (BioMed Central, 2012)
      Background: Malaria is one of the key targets within Goal 6 of the Millennium Development Goals (MDGs), whereby the disease needs to be halted and reversed by the year 2015. Several other international targets have been ...

    • Malaria Incidence Rates from Time Series of 2-Wave Panel Surveys 

      Castro, Marcia C.; Maheu-Giroux, Mathieu; Chiyaka, Christinah; Singer, Burton H. (Public Library of Science, 2016)
      Methodology to estimate malaria incidence rates from a commonly occurring form of interval-censored longitudinal parasitological data—specifically, 2-wave panel data—was first proposed 40 years ago based on the theory of ...

    • Malaria infection does not affect the sensitivity of peripheral receptor neurons in Anopheles stephensi 

      Grant, Alan; Muskavitch, Marc; O’Connell, Robert J (BioMed Central, 2013)
      Background: Mosquitoes transmit many important diseases including malaria, dengue and yellow fever. Disease transmission from one vertebrate host to another depends on repeated blood feedings by single mosquitoes. In order ...

    • Malaria Parasitemia and CD4 T Cell Count, Viral Load, and Adverse HIV Outcomes Among HIV-Infected Pregnant Women in Tanzania 

      Franke, Molly Forrest; Spiegelman, Donna Lynn; Ezeamama, A.; Aboud, S.; Msamanga, G. I.; Mehta, S.; Fawzi, Wafaie W. (American Society of Tropical Medicine and Hygiene, 2010)
      We examined the cross-sectional relationships between malaria parasitemia and CD4 T cell count and viral load among human immunodeficiency virus (HIV)-infected pregnant women. We then followed women to investigate whether ...

    • Malariometric indices from Iganga, Uganda: baseline characterization in preparation of GMZ2 vaccine trial 

      Kaddumukasa, Mark; Buwembo, William; Sekikubo, Musa; Naiwumbwe, Halima; Namusoke, Fatuma; Kiwuwa, Stephen; Oketch, Brenda; Noor, Ramadhani; Chilengi, Roma; Mworozi, Edison; Kironde, Fred (BioMed Central, 2014)
      Background: Malaria still remains the leading cause of childhood morbidity and mortality in Uganda. Interventions like malaria vaccines which reduce the malaria burden are needed in malaria endemic communities. There is ...

    • Male reproductive health and environmental xenoestrogens 

      Toppari, J; Larsen, JC; Christiansen, P; Giwercman, A; Grandjean, Philippe; Guillette LJ, Jr; Jégou, B; Jensen, TK; Jouannet, P; Keiding, N; Leffers, H; McLachlan, JA; Meyer, O; Müller, J; Rajpert-De Meyts, E; Scheike, T; Sharpe, R; Sumpter, J; Skakkebaek, NE (National Institute of Environmental Health Sciences, 2018-02-06)
      Male reproductive health has deteriorated in many countries during the last few decades. In the 1990s, declining semen quality has been reported from Belgium, Denmark, France, and Great Britain. The incidence of testicular ...

    • A male steroid controls female sexual behaviour in the malaria mosquito 

      Peng, Duo; Kakani, Evdoxia; Mameli, Enzo; Vidoudez, Charles; Mitchell, Sara; Merrihew, Gennifer E.; MacCoss, Michael J.; Adams, Kelsey; Rinvee, Tasneem A.; Shaw, W. Robert; Catteruccia, Flaminia (Springer Science and Business Media LLC, 2022-07-06)
      Insects, unlike vertebrates, are widely believed to lack male-biased sex steroid hormones1. In the malaria mosquito Anopheles gambiae, the ecdysteroid 20-hydroxyecdysone (20E) appears to have evolved to both control egg ...

    • Male Tobacco Smoke Load and Non-Lung Cancer Mortality Associations in Massachusetts 

      Leistikow, Bruce N; Kabir, Zubair; Connolly, Gregrory N.; Clancy, Luke; Alpert, Hillel R (BioMed Central, 2008)
      Background: Different methods exist to estimate smoking attributable cancer mortality rates (Peto and Ezzati methods, as examples). However, the smoking attributable estimates using these methods cannot be generalized to ...

    • Mammographic density and breast cancer risk: a mediation analysis 

      Rice, Megan S.; Bertrand, Kimberly A.; VanderWeele, Tyler J.; Rosner, Bernard A.; Liao, Xiaomei; Adami, Hans-Olov; Tamimi, Rulla M. (BioMed Central, 2016)
      Background: High mammographic density (MD) is a strong risk factor for breast cancer. However, it is unclear whether high MD is an intermediate phenotype or whether breast cancer risk factors influence breast cancer risk ...

    • Mammographic density and risk of breast cancer by age and tumor characteristics 

      Bertrand, Kimberly A; Tamimi, Rulla M; Scott, Christopher G; Jensen, Matthew R; Pankratz, V Shane; Visscher, Daniel; Norman, Aaron; Couch, Fergus; Shepherd, John; Fan, Bo; Chen, Yunn-Yi; Ma, Lin; Beck, Andrew H; Cummings, Steven R; Kerlikowske, Karla; Vachon, Celine M (BioMed Central, 2013)
      Introduction: Understanding whether mammographic density (MD) is associated with all breast tumor subtypes and whether the strength of association varies by age is important for utilizing MD in risk models. Methods: Data ...