Browsing SPH Scholarly Articles by Title

Now showing items 3927-3946 of 6362

    • Milk Intake, Circulating Levels of Insulin-Like Growth Factor-I, and Risk of Colorectal Cancer in Men 

      Ma, J.; Giovannucci, E.; Pollak, M.; Chan, J. M.; Gaziano, J. M.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Stampfer, Meir (Oxford University Press, 2001)
      Background: Milk and dietary calcium may have antiproliferative effects against colorectal cancer, but milk intake also raises serum levels of insulinlike growth factor-I (IGF-I). A high ratio of IGF-I to IGF-binding ...

    • Mineralogy affects geoavailability, bioaccessibility and bioavailability of zinc 

      Molina, Ramon M.; Schaider, Laurel A.; Donaghey, Thomas Clark; Shine, James P.; Brain, Joseph David (Elsevier BV, 2013)
      We correlated mineralogical and particle characteristics of Zn-containing particles with Zn geoavailability, bioaccessibility, and bioavailability following gavage and intranasal (IN) administration in rats. We compared ...

    • Minimal Phenotyping Yields Genome-Wide Association Signals of Low Specificity for Major Depression 

      Cai, Na; Revez, Joana A.; Adams, Mark J.; Andlauer, Till F. M.; Breen, Gerome; Byrne, Enda M.; Clarke, Toni-Kim; Forstner, Andreas J.; Grabe, Hans J.; Hamilton, Steven P.; Levinson, Douglas F.; Lewis, Cathryn M.; Lewis, Glyn; Martin, Nicholas G.; Milaneschi, Yuri; Mors, Ole; Muller-Myhsok, Bertram; Penninx, Brenda W. J. H.; Perlis, Roy H.; Pistis, Giorgio; Potash, James B.; Preisig, Martin; Shi, Jianxin; Smoller, Jordan W.; Streit, Fabien; Tiemeier, Henning; Uher, Rudolf; Van der Auwera, Sandra; Viktorin, Alexander; Weissman, Myrna M.; Kendler, Kenneth S.; Flint, Jonathan (Nature Publishing Group, 2020-03-30)
      Minimal phenotyping refers to the reliance on the use of a small number of self-report items for disease case identification, increasingly used in genome-wide association studies (GWAS). Here we report differences in genetic ...

    • Minimal sufficient causation and directed acyclic graphs 

      VanderWeele, Tyler J.; Robins, James M. (Institute of Mathematical Statistics, 2009)
      Notions of minimal sufficient causation are incorporated within the directed acyclic graph causal framework. Doing so allows for the graphical representation of sufficient causes and minimal sufficient causes on causal ...

    • Minimally Symptomatic Infection in an Ebola ‘Hotspot’: A Cross-Sectional Serosurvey 

      Richardson, Eugene T.; Kelly, J. Daniel; Barrie, Mohamed Bailor; Mesman, Annelies W.; Karku, Sahr; Quiwa, Komba; Marsh, Regan H.; Koedoyoma, Songor; Daboh, Fodei; Barron, Kathryn P.; Grady, Michael; Tucker, Elizabeth; Dierberg, Kerry L.; Rutherford, George W.; Barry, Michele; Jones, James Holland; Murray, Megan B.; Farmer, Paul E. (Public Library of Science, 2016)
      Introduction: Evidence for minimally symptomatic Ebola virus (EBOV) infection is limited. During the 2013–16 outbreak in West Africa, it was not considered epidemiologically relevant to published models or projections of ...

    • Misalignment between perceptions and actual global burden of disease: evidence from the US population 

      Siegel, Karen R.; Feigl, Andrea; Kishore, Sandeep P.; Stuckler, David (CoAction Publishing, 2011)
      Significant funding of health programs in low-income countries comes from external sources, mainly private donors and national development agencies of high-income countries. How these external funds are allocated remains ...

    • A Mismatch Between Patient Education Materials About Sickle Cell Disease and the Literacy Level of Their Intended Audience 

      McClure, Elizabeth; Ng, Jared; Vitzthum, Kelly; Rudd, Rima E. (Centers for Disease Control and Prevention (CDC), 2016)
      Introduction Despite the first goal of the 2010 National Action Plan to Improve Health Literacy, the literacy demands of much health information exceeds the reading skills of most US adults. The objective of this study ...

    • Misperceived Pre-pregnancy Body Weight Status Predicts Excessive Gestational Weight Gain: Findings from a US Cohort Study 

      Herring, Sharon J; Oken, Emily; Haines, Jess; Rich-Edwards, Janet Wilson; Rifas-Shiman, Sheryl Lynn; Kleinman, Ken Paul; Gillman, Matthew William (BioMed Central, 2008)
      Background: Excessive gestational weight gain promotes poor maternal and child health outcomes. Weight misperception is associated with weight gain in non-pregnant women, but no data exist during pregnancy. The purpose of ...

    • Missed opportunities to deliver intermittent preventive treatment for malaria to pregnant women 2003–2013: a systematic analysis of 58 household surveys in sub-Saharan Africa 

      Andrews, Kathryn G.; Lynch, Michael; Eckert, Erin; Gutman, Julie (BioMed Central, 2015)
      Background: Despite the availability of effective preventive measures, including intermittent preventive treatment for malaria during pregnancy (IPTp), malaria continues to cause substantial disease burden among pregnant ...

    • Missed opportunities: family history and behavioral risk factors in breast cancer risk assessment among a multiethnic group of women 

      Karliner, Leah S.; Napoles-Springer, Anna; Kerlikowske, Karla; Haas, Jennifer S.; Gregorich, Steven E.; Kaplan, Celia Patricia (Springer-Verlag, 2007)
      Background: Clinician’s knowledge of a woman’s cancer family history (CFH) and counseling about health-related behaviors (HRB) is necessary for appropriate breast cancer care. Objective: To evaluate whether clinicians ...

    • Missed Opportunities: Refusal to Confirm Reactive Rapid HIV Tests in the Emergency Department 

      Ganguli, Ishani; Collins, Jamie E.; Reichmann, William M.; Losina, Elena; Katz, Jeffrey Neil; Arbelaez, Christian; Donnell-Fink, Laurel A.; Walensky, Rochelle P. (Public Library of Science, 2013)
      Background: HIV infection remains a major US public health concern. While HIV-infected individuals now benefit from earlier diagnosis and improved treatment options, progress is tempered by large numbers of newly diagnosed ...

    • Mitigating disrespect and abuse during childbirth in Tanzania: an exploratory study of the effects of two facility-based interventions in a large public hospital 

      Ratcliffe, Hannah L.; Sando, David; Lyatuu, Goodluck Willey; Emil, Faida; Mwanyika-Sando, Mary; Chalamilla, Guerino; Langer, Ana; McDonald, Kathleen P. (BioMed Central, 2016)
      Background: There is emerging evidence that disrespect and abuse (D&A) during facility-based childbirth is prevalent in countries throughout the world and a barrier to achieving good maternal health outcomes. However, much ...

    • Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress 

      Shaughnessy, Daniel T.; McAllister, Kimberly; Worth, Leroy; Haugen, Astrid C.; Meyer, Joel N.; Domann, Frederick E.; Van Houten, Bennett; Mostoslavsky, Raul; Bultman, Scott J.; Baccarelli, Andrea A.; Begley, Thomas J.; Sobol, Robert W.; Hirschey, Matthew D.; Ideker, Trey; Santos, Janine H.; Copeland, William C.; Tice, Raymond R.; Balshaw, David M.; Tyson, Frederick L. (NLM-Export, 2014)
      Background: Cells respond to environmental stressors through several key pathways, including response to reactive oxygen species (ROS), nutrient and ATP sensing, DNA damage response (DDR), and epigenetic alterations. ...

    • Mitochondrial haplogroups modify the effect of black carbon on age-related cognitive impairment 

      Colicino, Elena; Power, Melinda C; Cox, David G; Weisskopf, Marc G; Hou, Lifang; Alexeeff, Stacy E; Sanchez-Guerra, Marco; Vokonas, Pantel; Spiro III, Avron; Schwartz, Joel; Baccarelli, Andrea A (BioMed Central, 2014)
      Background: Traffic-related air pollution has been linked with impaired cognition in older adults, possibly due to effects of oxidative stress on the brain. Mitochondria are the main source of cellular oxidation. Haplogroups ...

    • Mitochondrial iron chelation ameliorates cigarette-smoke induced bronchitis and emphysema in mice 

      Cloonan, Suzanne M.; Glass, Kimberly; Laucho-Contreras, Maria E.; Bhashyam, Abhiram R.; Cervo, Morgan; Pabón, Maria A.; Konrad, Csaba; Polverino, Francesca; Siempos, Ilias I.; Perez, Elizabeth; Mizumura, Kenji; Ghosh, Manik C.; Parameswaran, Harikrishnan; Williams, Niamh C.; Rooney, Kristen T.; Chen, Zhi-Hua; Goldklang, Monica P.; Yuan, Guo-Cheng; Moore, Stephen C.; Demeo, Dawn L.; Rouault, Tracey A.; D’Armiento, Jeanine M.; Schon, Eric A.; Manfredi, Giovanni; Quackenbush, John; Mahmood, Ashfaq; Silverman, Edwin K.; Owen, Caroline A.; Choi, Augustine M.K. (2015)
      Chronic obstructive pulmonary disease (COPD) is linked to both cigarette smoking and genetic determinants. We have previously identified iron-responsive element binding protein 2 (IRP2) as an important COPD susceptibility ...

    • Mitochondrial Variations in Non-Small Cell Lung Cancer (NSCLC) Survival 

      Wang, Zhaoxi; Choi, Sojung; Lee, Jinseon; Huang, Yen-Tsung; Chen, Feng; Zhao, Yang; Lin, Xihong; Neuberg, Donna; Kim, Jhingook; Christiani, David C (Libertas Academica, 2015)
      Mutations in the mtDNA genome have long been suspected to play an important role in cancer. Although most cancer cells harbor mtDNA mutations, the question of whether such mutations are associated with clinical prognosis ...

    • Mitogen-Activated Protein Kinases Regulate Susceptibility to Ventilator-Induced Lung Injury 

      Dolinay, Tamás; Wu, Wei; Kaminski, Naftali; Ifedigbo, Emeka; Kaynar, A. Murat; Szilasi, Mária; Watkins, Simon C.; Ryter, Stefan W.; Hoetzel, Alexander; Choi, Augustine M.K. (Public Library of Science, 2008)
      Background: Mechanical ventilation causes ventilator-induced lung injury in animals and humans. Mitogen-activated protein kinases have been implicated in ventilator-induced lung injury though their functional significance ...

    • MM-ChIP enables integrative analysis of cross-platform and between-laboratory ChIP-chip or ChIP-seq data 

      Chen, Yiwen; Meyer, Clifford; Liu, Tao; Li, Wei; Liu, Jun; Liu, Xiaole (Shirley) Shirley (Springer Science + Business Media, 2011)
      The ChIP-chip and ChIP-seq techniques enable genome-wide mapping of in vivo protein-DNA interactions and chromatin states. The cross-platform and between-laboratory variation poses a challenge to the comparison and integration ...

    • MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212 

      Rosa, Valentina La; Poce, Giovanna; Canseco, Julio Ortiz; Buroni, Silvia; Pasca, Maria Rosalia; Biava, Mariangela; Raju, Ravikiran M.; Porretta, Giulio Cesare; Alfonso, Salvatore; Battilocchio, Claudio; Javid, Babak; Sorrentino, Flavia; Ioerger, Thomas R.; Sacchettini, James C.; Manetti, Fabrizio; Botta, Maurizio; Logu, Alessandro De; Rubin, Eric J.; Rossi, Edda De (American Society for Microbiology, 2012)
      The 1,5-diarylpyrrole derivative BM212 was previously shown to be active against multidrug-resistant clinical isolates and Mycobacterium tuberculosis residing within macrophages as well as against Mycobacterium avium and ...

    • Mobile HIV Screening in Cape Town, South Africa: Clinical Impact, Cost and Cost-Effectiveness 

      Bassett, Ingrid V.; Govindasamy, Darshini; Erlwanger, Alison S.; Hyle, Emily P.; Kranzer, Katharina; van Schaik, Nienke; Noubary, Farzad; Paltiel, A. David; Wood, Robin; Walensky, Rochelle P.; Losina, Elena; Bekker, Linda-Gail; Freedberg, Kenneth A. (Public Library of Science, 2014)
      Background: Mobile HIV screening may facilitate early HIV diagnosis. Our objective was to examine the cost-effectiveness of adding a mobile screening unit to current medical facility-based HIV testing in Cape Town, South ...