Browsing SPH Scholarly Articles by Title
Now showing items 3958-3977 of 6362
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Modeling Spatial Patterns of Traffic-Related Air Pollutants in Complex Urban Terrain
(National Institute of Environmental Health Sciences, 2011)Background: The relationship between traffic emissions and mobile-source air pollutant concentrations is highly variable over space and time and therefore difficult to model accurately, especially in urban settings with ... -
Modeling the Comparative Impact of Individual Quarantine vs. Active Monitoring of Contacts for the Mitigation of COVID-19
(2020-03-08)Individual quarantine and active monitoring of contacts are core disease control strategies, particularly for emerging infectious diseases such as Coronavirus Disease 2019 (COVID-19). To estimate the comparative efficacy ... -
Modeling the Cost Effectiveness of Neuroimaging-Based Treatment of Acute Wake-Up Stroke
(Public Library of Science, 2016)Background: Thrombolytic treatment (tissue-type plasminogen activator [tPA]) is only recommended for acute ischemic stroke patients with stroke onset time <4.5 hours. tPA is not recommended when stroke onset time is unknown. ... -
Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data
(BioMed Central, 2012)Background: Analysis of US claims data from April 2010 to June 2011 estimated that 39% of the 13-valent pneumococcal conjugate vaccine (PCV13) catch-up eligible cohort would ever receive the catch-up vaccination; a previous ... -
Modelling national HIV/AIDS epidemics: revised approach in the UNAIDS Estimation and Projection Package 2011
(BMJ Publishing Group, 2012)Objective: United Nations Programme on HIV/AIDS reports regularly on estimated levels and trends in HIV/AIDS epidemics, which are evaluated using an epidemiological model within the Estimation and Projection Package (EPP). ... -
Modelling seasonal variations in the age and incidence of Kawasaki disease to explore possible infectious aetiologies
(The Royal Society, 2012)The average age of infection is expected to vary during seasonal epidemics in a way that is predictable from the epidemiological features, such as the duration of infectiousness and the nature of population mixing. However, ... -
Modelling Strategic Interventions in a Population with a Total Fertility Rate of 8.3: A Cross-Sectional Study of Idjwi Island, DRC
(BioMed Central, 2012)Background: Idjwi, an island of approximately 220,000 people, is located in eastern DRC and functions semi-autonomously under the governance of two kings (mwamis). At more than 8 live births per woman, Idjwi has one of the ... -
Moderate Alcohol Consumption and Risk of Coronary Heart Disease Among Women with Type 2 Diabetes Mellitus
(American Heart Association, 2000)Background-Moderate alcohol consumption is associated with reduced risk for coronary heart disease (CI-ID) in generally healthy populations. We assessed prospectively the association between moderate alcohol intake and CHD ... -
Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors
(1999)Objective To summarise quantitatively the association between moderate alcohol intake and biological markers of risk of coronary heart disease and to predict how these changes would lower the risk.Design Meta-analysis of ... -
Moderate alcohol intake and markers of inflammation and endothelial dysfunction among diabetic men
(Springer Verlag, 2004)Aims/hypothesis. Type 2 diabetes mellitus is characterised by heightened inflammation and endothelial dysfunction. Moderate alcohol intake has been associated with a reduced risk of cardiovascular disease in Type 2 diabetic ... -
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
(BioMed Central, 2014)In comparative high-throughput sequencing assays, a fundamental task is the analysis of count data, such as read counts per gene in RNA-seq, for evidence of systematic changes across experimental conditions. Small replicate ... -
Modern mammography screening and breast cancer mortality: population study
(BMJ Publishing Group Ltd., 2014)Objective: To evaluate the effectiveness of contemporary mammography screening using individual information about screening history and breast cancer mortality from public screening programmes. Design: Prospective cohort ... -
Modest Attenuation of HIV-1 Vpu Alleles Derived from Elite Controller Plasma
(Public Library of Science, 2015)In the absence of antiretroviral therapy, infection with human immunodeficiency virus type 1 (HIV-1) can typically not be controlled by the infected host and results in the development of acquired immunodeficiency. In rare ... -
Modifiable Cardiovascular Disease Risk Factors among Indigenous Populations
(Hindawi Publishing Corporation, 2014)Objective:. To identify modifiable cardio-metabolic and lifestyle risk factors among indigenous populations from Australia (Aboriginal Australians/Torres Strait Islanders), New Zealand (Māori), and the United States (American ... -
Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study
(BioMed Central, 2013)Background: Previous studies found effect modification of associations between traffic-related air pollution and cardiovascular outcomes by polymorphisms in the hemochromatosis gene (HFE). As traffic-related air pollution ... -
Modification of the Association Between Obesity and Lethal Prostate Cancer by TMPRSS2:ERG
(Oxford University Press, 2013)TMPRSS2:ERG is a hormonally regulated gene fusion present in about half of prostate tumors. We investigated whether obesity, which deregulates several hormonal pathways, interacts with TMPRSS2:ERG to impact prostate cancer ... -
A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals
(Public Library of Science (PLoS), 2018)Background Ebola virus (EBOV) caused more than 11,000 deaths during the 2013–2016 epidemic in West Africa without approved vaccines or immunotherapeutics. Despite its high lethality in some individuals, EBOV infection can ... -
A Modified Janus Cassette (Sweet Janus) to Improve Allelic Replacement Efficiency by High-Stringency Negative Selection in Streptococcus pneumoniae
(Public Library of Science, 2014)The Janus cassette permits marker-free allelic replacement or knockout in streptomycin-resistant Streptococcus pneumoniae (pneumococcus) through sequential positive and negative selection. Spontaneous revertants of Janus ... -
Modified Mediterranean Diet Score and Cardiovascular Risk in a North American Working Population
(Public Library of Science, 2014)Introduction: Greater adherence to a Mediterranean diet is linked to lower risk for cardiovascular morbidity/mortality in studies of Mediterranean cohorts, older subjects, and/or those with existing health conditions. No ...