Browsing SPH Scholarly Articles by Title
Now showing items 4416-4435 of 6362
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Patterns of Genomic Differentiation between Ecologically Differentiated M and S Forms of Anopheles gambiae in West and Central Africa
(Oxford University Press, 2012)Anopheles gambiae M and S are thought to be undergoing ecological speciation by adapting to different larval habitats. Toward an improved understanding of the genetic determinants and evolutionary processes shaping their ... -
Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia
(BioMed Central, 2015)Introduction: Several pharmacologic treatments are available for fibromyalgia, but little is known about the comparative effectiveness of these treatments on health care utilization. Methods: Using US commercial insurance ... -
Patterns of postnatal growth in HIV-infected and HIV-exposed children
(Oxford University Press (OUP), 2009)HIV infection can contribute to disturbances in both linear growth and weight gain in early childhood, with disturbances often apparent as early as 3 mo of age. There is little evidence for a difference in the early growth ... -
Patterns of Proliferative Activity in the Colonic Crypt Determine Crypt Stability and Rates of Somatic Evolution
(Public Library of Science, 2013)Epithelial cells in the colon are arranged in cylindrical structures called crypts in which cellular proliferation and migration are tightly regulated. We hypothesized that the proliferation patterns of cells may determine ... -
Patterns of Pulmonary Dysfunction in Asbestos Workers: A Cross-Sectional Study
(BioMed Central, 2010)Background: Restrictive patterns of pulmonary function abnormalities associated with asbestos exposure are well described. Studies are less consistent, however, regarding the association of asbestos inhalation with airway ... -
Patterns of Weight Gain in Middle-Aged and Older US Adults, 1992–2010
(Lippincott Williams & Wilkins, 2015)Background: Cross-sectional analyses of national data have found that persons with high baseline body mass index (BMI) gain weight faster than persons at the median and that those whose weight was below the median gain ... -
Paucity of HPV-Related Head and Neck Cancers (HNC) in Nigeria
(Public Library of Science, 2016)Introduction: The burden of HPV-related Head and Neck Cancers (HNC) has been rising in the U.S. and other developed countries but this trend has not been reported in Africa. Objective of study was to evaluate the prevalence ... -
Paying Physicians to Prescribe Generic Drugs and Follow-On Biologics in the United States
(Public Library of Science, 2015)Aaron Kesselheim and colleagues examine potential strategies to promote greater prescribing of generic drugs and follow-on biologics -
Payment Reform Is About to Become a Reality
(American Medical Association (AMA), 2015) -
PBAT: A comprehensive software package for genome-wide association analysis of complex family-based studies
(BioMed Central, 2005)The PBAT software package (v2.5) provides a unique set of tools for complex family-based association analysis at a genome-wide level. PBAT can handle nuclear families with missing parental genotypes, extended pedigrees ... -
PBDE flame retardants, thyroid disease, and menopausal status in U.S. women
(BioMed Central, 2016)Background: Women have elevated rates of thyroid disease compared to men. Environmental toxicants have been implicated as contributors to this dimorphism, including polybrominated diphenyl ethers (PBDEs), flame retardant ... -
PCI Proteins eIF3e and eIF3m Define Distinct Translation Initiation Factor 3 Complexes
(BioMed Central, 2005)Background: PCI/MPN domain protein complexes comprise the 19S proteasome lid, the COP9 signalosome (CSN), and eukaryotic translation initiation factor 3 (eIF3). The eIF3 complex is thought to be composed of essential core ... -
PCSK7 Genotype Modifies Effect of a Weight-Loss Diet on 2-Year Changes of Insulin Resistance: The POUNDS LOST Trial
(American Diabetes Association, 2015)OBJECTIVE A common variant rs236918 in the PCSK7 gene has the strongest association with iron homeostasis and is related to insulin resistance. Dietary carbohydrate (CHO) modulates the genetic effect on insulin resistance. ... -
PD-1 Blockade in Chronically HIV-1-Infected Humanized Mice Suppresses Viral Loads
(Public Library of Science, 2013)An estimated 34 million people are living with HIV worldwide (UNAIDS, 2012), with the number of infected persons rising every year. Increases in HIV prevalence have resulted not only from new infections, but also from ... -
PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease
(BioMed Central, 2012)Background: PDLIM2 is essential for the termination of the inflammatory transcription factors NF-κB and STAT but is dispensable for the development of immune cells and immune tissues/organs. Currently, it remains unknown ... -
Pediatric forearm fractures with in situ intramedullary implants
(Springer Berlin Heidelberg, 2016)Purpose The purpose of this investigation is to present our institutional experience with fractures of the pediatric forearm with in situ intramedullary nails. Methods: Six patients treated at our institution for forearm ... -
Pediatric Health-Related Quality of Life: A Structural Equation Modeling Approach
(Public Library of Science, 2014)Objectives: One of the most referenced theoretical frameworks to measure Health Related Quality of Life (HRQoL) is the Wilson and Cleary framework. With some adaptions this framework has been validated in the adult population, ... -
Pediatric hereditary angioedema
(BlackWell Publishing Ltd, 2013)Hereditary angioedema (HAE) is a lifelong illness characterized by recurrent swelling of the skin, intestinal tract, and, ominously, the upper airway. It is caused by inadequate activity of the protein C1-inhibitor, with ... -
Pediatricians’ Practice Location Choice—Evaluating the Effect of Japan’s 2004 Postgraduate Training Program on the Spatial Distribution of Pediatricians
(Japan Epidemiological Association, 2014)Objectives: To explore determinants of change in pediatrician supply in Japan, and examine impacts of a 2004 reform of postgraduate medical education on pediatricians’ practice location choice. Methods: Data were compiled ... -
Peer Support and Exclusive Breastfeeding Duration in Low and Middle-Income Countries: A Systematic Review and Meta-Analysis
(Public Library of Science, 2012)Objective: To examine the effect of peer support on duration of exclusive breastfeeding (EBF) in low and middle-income countries (LMICs). Data Sources Medline, EMBASE, and Cochrane Central Register for Controlled Trials ...