Browsing SPH Scholarly Articles by Title

Now showing items 4533-4552 of 6362

    • Placental mitochondrial DNA content and placental abruption: a pilot study 

      Qiu, Chunfang; Sanchez, Sixto E.; Hevner, Karin; Enquobahrie, Daniel A.; Williams, Michelle A. (BioMed Central, 2015)
      Background: Mitochondrial biogenesis and adequate energy production are important for embryogenesis and placentation. Previous studies documented alterations in maternal blood mitochondrial DNA (mtDNA) copy number—a marker ...

    • Placental mitochondrial methylation and exposure to airborne particulate matter in the early life environment: An ENVIRONAGE birth cohort study 

      Janssen, Bram G; Byun, Hyang-Min; Gyselaers, Wilfried; Lefebvre, Wouter; Baccarelli, Andrea A; Nawrot, Tim S (Taylor & Francis, 2015)
      Most research to date has focused on epigenetic modifications in the nuclear genome, with little attention devoted to mitochondrial DNA (mtDNA). Placental mtDNA content has been shown to respond to environmental exposures ...

    • Placental Pathology Associated with Household Air Pollution in a Cohort of Pregnant Women from Dar es Salaam, Tanzania 

      Wylie, Blair J.; Matechi, Emmanuel; Kishashu, Yahya; Fawzi, Wafaie; Premji, Zul; Coull, Brent A.; Hauser, Russ; Ezzati, Majid; Roberts, Drucilla J. (National Institute of Environmental Health Sciences, 2016)
      Background: Smoke from the burning of biomass fuels has been linked with adverse pregnancy outcomes such as low birth weight, stillbirth, and prematurity. Objective: To identify potential underlying mechanisms of adverse ...

    • Placing a Price on Medical Device Innovation: The Example of Total Knee Arthroplasty 

      Suter, Lisa G.; Paltiel, A. David; Rome, Benjamin Newman; Solomon, Daniel Hal; Thornhill, Thomas Stone; Abrams, Stanley K.; Katz, Jeffrey Neil; Losina, Elena (Public Library of Science, 2013)
      Background: Total knee arthroplasty (TKA) is common, effective, and cost-effective. Innovative implants promising reduced long-term failure at increased cost are under continual development. We sought to define the implant ...

    • Plant-Based Dietary Patterns and Incidence of Type 2 Diabetes in US Men and Women: Results from Three Prospective Cohort Studies 

      Satija, Ambika; Bhupathiraju, Shilpa N.; Rimm, Eric B.; Spiegelman, Donna; Chiuve, Stephanie E.; Borgi, Lea; Willett, Walter C.; Manson, JoAnn E.; Sun, Qi; Hu, Frank B. (Public Library of Science, 2016)
      Background: Plant-based diets have been recommended to reduce the risk of type 2 diabetes (T2D). However, not all plant foods are necessarily beneficial. We examined the association of an overall plant-based diet and ...

    • Plasma 1,25-Dihydroxy- and 25-Hydroxyvitamin D and Subsequent Risk of Prostate Cancer 

      Platz, Elizabeth A.; Leitzmann, Michael F.; Hollis, Bruce W.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Giovannucci, Edward (Springer (part of Springer Nature), 2004)
      Objective: The hormone 1,25-dihydroxyvitamin D (1,25(OH)(2)D) promotes prostate epithelial cell differentiation in vitro and thus, several groups have hypothesized that men who systemically have lower levels of 1,25( OH) ...

    • Plasma 25-hydroxyvitamin D and colorectal cancer risk according to tumour immunity status 

      Song, Mingyang; Nishihara, Reiko; Wang, Molin; Chan, Andrew; Qian, Zhi Rong; Inamura, Kentaro; Zhang, Xuehong; Ng, Kimmie; Kim, Sun; Mima, Kosuke; Sukawa, Yasutaka; Nosho, Katsuhiko; Fuchs, Charles; Giovannucci, Edward; Wu, Kana; Ogino, Shuji (BMJ Publishing Group, 2016)
      Objective Evidence suggests protective effects of vitamin D and antitumour immunity on colorectal cancer risk. Immune cells in tumour microenvironment can convert 25-hydroxyvitamin D [25(OH)D] to bioactive 1 alpha, ...

    • Plasma 25-Hydroxyvitamin D and Progression to Diabetes in Patients at Risk for Diabetes 

      Pittas, Anastassios G.; Nelson, Jason; Mitri, Joanna; Hillmann, William; Garganta, Cheryl; Nathan, David Matthew; Hu, Frank B.; Dawson-Hughes, Bess (American Diabetes Association, 2012)
      OBJECTIVE To investigate the association between vitamin D status, assessed by plasma 25-hydroxyvitamin D, and risk of incident diabetes. RESEARCH DESIGN AND METHODS Prospective observational study with a mean follow-up ...

    • Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II 

      Eliassen, A. Heather; Spiegelman, Donna; Hollis, Bruce W.; Horst, Ronald L.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Hankinson, Susan E. (BMC, 2011)
      Introduction: Experimental evidence indicates vitamin D may play an important role in breast cancer etiology but epidemiologic evidence to date is inconsistent. Vitamin D comes from dietary intake and sun exposure and ...

    • Plasma 25-Hydroxyvitamin D and Risk of Pancreatic Cancer 

      Wolpin, Brian M.; Ng, Kimmie; Bao, Ying; Kraft, Peter; Stampfer, Meir; Michaud, Dominique S.; Ma, Jing; Buring, Julie E.; Sesso, Howard D.; Lee, I-Min; Rifai, Nader; Cochrane, Barbara B.; Wactawski-Wende, Jean; Chlebowski, Rowan T.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Manson, JoAnn E.; Giovannucci, Edward L.; Fuchs, Charles S. (American Association for Cancer Research, 2012)
      Background: Laboratory studies suggest that vitamin D may inhibit pancreatic cancer cell growth. However, epidemiologic studies of vitamin D and pancreatic cancer risk have been conflicting. Methods: To determine whether ...

    • Plasma 25-hydroxyvitamin D and risk of premenstrual syndrome in a prospective cohort study 

      Bertone-Johnson, Elizabeth R; Johnson, Susan R; Hankinson, Susan E; Forger, Nancy G; Powers, Sally I; Willett, Walter C; Manson, JoAnn E (BioMed Central, 2014)
      Background: Moderate to severe premenstrual syndrome (PMS) affects 8–20 percent of premenopausal women. Previous studies suggest that high dietary vitamin D intake may reduce risk. However, vitamin D status is influenced ...

    • Plasma 25-hydroxyvitamin D concentration and metabolic syndrome among middle-aged and elderly Chinese individuals 

      Yu, Zhijie; Pan, An; Franco, Oscar H.; Li, Huaixing; Yang, Xilin; Lin, Xu; Lu, Ling; Hu, Frank B.; Li, Xiaoying; Chen, Yan (American Diabetes Association, 2009)
      OBJECTIVE—To evaluate the association between 25-hydroxyvitamin D [25(OH)D] and metabolic syndrome in the Chinese population. RESEARCH DESIGN AND METHODS—Plasma 25(OH)D was measured in a cross-sectional sample of 1,443 men ...

    • Plasma Adiponectin Concentrations Are Associated with Body Composition and Plant-Based Dietary Factors in Female Twins 

      Cassidy, A.; Skidmore, P.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Welch, A.; Fairweather-Tait, S.; Skinner, J.; Burling, K.; Richards, J. B.; Spector, T. D.; MacGregor, A. J. (Oxford University Press, 2008)
      Circulating adiponectin is emerging as an important link between obesity, type 2 diabetes, and cardiovascular disease (CVD). However, the spectrum of lifestyle factors that modulate the adiponectin concentration remains ...

    • Plasma Adiponectin Levels and Risk of Myocardial Infarction in Men 

      Pischon, Tobias; Hotamisligil, Gokhan; Girman, Cynthia; Rifai, Nader; Hu, Frank; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600 (American Medical Association (AMA), 2004-04-14)
      Context Adiponectin, a recently discovered adipocyte-derived peptide, is involved in the regulation of insulin sensitivity and lipid oxidation and, purportedly, in the development of atherosclerosis and coronary heart ...

    • Plasma Alkylresorcinols, Biomarkers of Whole-Grain Wheat and Rye Intake, and Incidence of Colorectal Cancer 

      Kyrø, Cecilie; Olsen, Anja; Landberg, Rikard; Skeie, Guri; Loft, Steffen; Åman, Per; Leenders, Max; Dik, Vincent K.; Siersema, Peter D.; Pischon, Tobias; Christensen, Jane; Overvad, Kim; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Cottet, Vanessa; Kühn, Tilman; Chang-Claude, Jenny; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Trichopoulos, Dimitrios; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Peeters, Petra H.; Weiderpass, Elisabete; Bakken, Toril; Åsli, Lene Angell; Argüelles, Marcial; Jakszyn, Paula; Sánchez, María-José; Amiano, Pilar; Huerta, José María; Barricarte, Aurelio; Ljuslinder, Ingrid; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Ferrari, Pietro; Freisling, Heinz; Jenab, Mazda; Gunter, Marc J.; Murphy, Neil; Riboli, Eilo; Tjønneland, Anne; Bueno-de-Mesquita, H.B(as). (Oxford University Press, 2013)
      Background: Few studies have investigated the association between whole-grain intake and colorectal cancer. Because whole-grain intake estimation might be prone to measurement errors, more objective measures (eg, biomarkers) ...

    • Plasma antioxidants, genetic variation in SOD2, CAT, GPX1, GPX4, and prostate cancer survival 

      Blarigan, Erin Van; Ma, Jing; Kenfield, Stacey A.; Stampfer, Meir; Sesso, Howard D.; Giovannucci, Edward L.; Witte, John S.; Erdman, John W. Jr.; Chan, June M.; Penney, Kathryn L. (American Association for Cancer Research, 2014)
      Background: Antioxidants may reduce risk of aggressive prostate cancer, and single-nucleotide polymorphisms (SNP) in antioxidant genes may modify this association. Methods: We used Cox proportional hazards regression to ...

    • Plasma Aβ, homocysteine, and cognition: The Vitamin Intervention for Stroke Prevention (VISP) trial 

      Viswanathan, A.; Raj, S.; Greenberg, S. M.; Stampfer, M.; Campbell, S.; Hyman, B. T.; Irizarry, M. C. (American Academy of Neurology, 2009)

    • Plasma concentration of cross-linked fibrin degradation product (D- dimer) and the risk of future myocardial infarction among apparently healthy men 

      Ridker, P. M.; Hennekens, C. H.; Cerskus, A.; Stampfer, Meir (American Heart Association, 1994)

    • Plasma Concentration of Interleukin-6 and the Risk of Future Myocardial Infarction Among Apparently Healthy Men 

      Ridker, P. M.; Rifai, N.; Stampfer, Meir; Hennekens, C. H. (American Heart Association, 2000)
      Background-Interleukin-6 (IL-6) plays a central role in inflammation and tissue injury. However, epidemiological data evaluating the role of IL-6 in atherogenesis are sparse.Methods and Results-In a prospective study ...

    • Plasma Concentrations, Efficacy and Safety of Efavirenz in HIV-Infected Adults Treated for Tuberculosis in Cambodia (ANRS 1295-CIPRA KH001 CAMELIA Trial) 

      Borand, Laurence; Madec, Yoann; Laureillard, Didier; Chou, Monidarin; Marcy, Olivier; Pheng, Phearavin; Prak, Narom; Kim, Chindamony; Lak, Khemarin Kim; Hak, Chanroeun; Dim, Bunnet; Nerrienet, Eric; Fontanet, Arnaud; Sok, Thim; Goldfeld, Anne E.; Blanc, François-Xavier; Taburet, Anne-Marie (Public Library of Science, 2014)
      Objective: To assess efavirenz plasma concentrations and their association with treatment efficacy and tolerance of efavirenz 600 mg daily in HIV-tuberculosis co-infected patients. Methods: HIV-infected adults with CD4+ T ...