Now showing items 871-890 of 6362

    • The Burden of Disease and Injury in the United States 1996 

      Begg, Stephen; Tomijima, Niels; Majmudar, Meghna; Bulzacchelli, Maria T; Ebrahim, Shahul; Gaber Kreiser, Jessica; Hogan, Mollie; Michaud, Catherine M.; McKenna, Matthew; Ezzati, Majid; Salomon, Joshua A.; Murray, Christopher (BioMed Central, 2006)
      Background: Burden of disease studies have been implemented in many countries using the Disability-Adjusted Life Year (DALY) to assess major health problems. Important objectives of the study were to quantify intra-country ...
    • The burden of hypertension in sub-Saharan Africa: a four-country cross sectional study 

      Guwatudde, David; Nankya-Mutyoba, Joan; Kalyesubula, Robert; Laurence, Carien; Adebamowo, Clement; Ajayi, IkeOluwapo; Bajunirwe, Francis; Njelekela, Marina; Chiwanga, Faraja S.; Reid, Todd; Volmink, Jimmy; Adami, Hans-Olov; Holmes, Michelle D.; Dalal, Shona (BioMed Central, 2015)
      Background: Hypertension, the leading single cause of morbidity and mortality worldwide, is a growing public health problem in sub-Saharan Africa (SSA). Few studies have estimated and compared the burden of hypertension ...
    • The Burden of Oral Disease among Perinatally HIV-Infected and HIV-Exposed Uninfected Youth 

      Moscicki, Anna-Barbara; Yao, Tzy-Jyun; Ryder, Mark I.; Russell, Jonathan S.; Dominy, Stephen S.; Patel, Kunjal; McKenna, Matt; Van Dyke, Russell B.; Seage, George R.; Hazra, Rohan (Public Library of Science, 2016)
      Objective: To compare oral health parameters in perinatally HIV-infected (PHIV) and perinatally HIV-exposed but uninfected youth (PHEU). Methods: In a cross-sectional substudy within the Pediatric HIV/AIDS Cohort Study, ...
    • The burden of pediatric diarrhea: a cross-sectional study of incurred costs and perceptions of cost among Bolivian families 

      Burke, Rachel M; Rebolledo, Paulina A; Embrey, Sally R; Wagner, Laura; Cowden, Carter L; Kelly, Fiona M; Smith, Emily Rose; Iñiguez, Volga; Leon, Juan (Springer Science + Business Media, 2013)
      Background: Worldwide, acute gastroenteritis represents an enormous public health threat to children under five years of age, causing one billion episodes and 1.9 to 3.2 million deaths per year. In Bolivia, which has one ...
    • Burden of severe maternal morbidity and association with adverse birth outcomes in sub–Saharan Africa and south Asia: protocol for a prospective cohort study. 

      Fawzi, Wafaie W. (Edinburgh University Global Health Society, 2016)
      OBJECTIVES: The AMANHI morbidity study aims to quantify and describe severe maternal morbidities and assess their associations with adverse maternal, fetal and newborn outcomes in predominantly rural areas of nine sites ...
    • Burden of smoking on cause-specific mortality: application to the Nurses’ Health Study 

      Kenfield, Stacey A.; Wei, Esther K.; Rosner, Bernard A.; Glynn, Robert J.; Stampfer, Meir; Colditz, Graham A. (BMJ Publishing Group, 2010)
      Objective The burden of smoking on six causes of death in women was evaluated using various novel modelling approaches.Design A prospective US-based nationwide cohort study.Participants 102 635 women in the Nurses' Health ...
    • C-Reactive Protein (CRP) Gene Polymorphisms, CRP Levels, and Risk of Incident Coronary Heart Disease in Two Nested Case-Control Studies 

      Pai, Jennifer Kai-cha; Mukamal, Ken J.; Rexrode, Kathryn Marian; Rimm, Eric B. (Public Library of Science, 2008)
      Background: C-reactive protein (CRP), an acute phase reactant and marker of inflammation, has been shown to predict risk of incident cardiovascular events. However, few studies have comprehensively examined six common ...
    • C-Reactive Protein and Incident Cardiovascular Events Among Men with Diabetes 

      Schulze, M. B.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Li, T.; Rifai, N.; Stampfer, Meir; Hu, F. B. (American Diabetes Association, 2004)
      Objective - Several large prospective studies have shown that baseline levels of C-reactive protein (CRP) are an independent predictor of cardiovascular events among apparently healthy individuals. However, prospective ...
    • C-Reactive Protein and the Incidence of Macular Degeneration – Pooled Analysis of 5 Cohorts 

      Mitta, Vinod P.; Christen, William G.; Glynn, Robert J.; Semba, Richard D.; Ridker, Paul M.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hankinson, Susan E.; Schaumberg, Debra A. (2013)
      Importance: This study adds to the evidence that elevated levels of high-sensitivity C-reactive protein (hsCRP) predict future risk of age-related macular degeneration (AMD). This information might shed light on underlying ...
    • C-reactive protein independently predicts HIV-related outcomes among women and children in a resource-poor setting 

      Drain, Paul K; Kupka, Roland; Msamanga, Gernard I; Urassa, Willy; Mugusi, Ferdinand; Fawzi, Wafaie W. (Ovid Technologies (Wolters Kluwer Health), 2007)
      Objective To evaluate C-reactive protein (CRP), an inflammatory marker, as a predictor of HIV-related outcomes among women and children in a resource-poor setting. Design We measured serum CRP concentration among ...
    • C-reactive Protein, Interleukin-6, Soluble Tumor Necrosis Factor Α Receptor 2 and Incident Clinical Depression 

      Chocano-Bedoya, Patricia; Mirzaei, Fariba; O’Reilly, Eilis J.; Lucas, Michel; Okereke, Olivia; Hu, Frank; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Ascherio, Alberto (Elsevier, 2014)
    • Cadmium Exposure and Neurodevelopmental Outcomes in U.S. Children 

      Ciesielski, Timothy; Weuve, Jennifer Lynn; Bellinger, David C.; Schwartz, Joel David; Lanphear, Bruce; Wright, Robert O. (National Institute of Environmental Health Sciences, 2012)
      Background: Low-level environmental cadmium exposure in children may be associated with adverse neurodevelopmental outcomes. Objective: Our aim was to evaluate associations between urinary cadmium concentration and reported ...
    • Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls 

      Petersen, Maria Skaalum; Halling, Jónrit; Damkier, Per; Nielsen, Flemming; Grandjean, Philippe; Weihe, Pal; Brøsen, Kim (Springer Nature, 2006)
      Objective To investigate the CYP1A2 phenotype distribution in a population with an increased exposure to polychlorinated biphenyls (PCBs) that would likely induce an increased activity of this enzyme. Further, to ...
    • Calcineurin activation causes retinal ganglion cell degeneration 

      Qu, Juan; Matsouaka, Roland Albert; Betensky, Rebecca Aubrey; Hyman, Bradley Theodore; Grosskreutz, Cynthia Lee (Molecular Vision, 2012)
      Purpose: We previously reported that calcineurin, a Ca2+/calmodulin-dependent serine/threonine phosphatase, is activated and proposed that it participates in retinal ganglion cell (RGC) apoptosis in two rodent ocular ...
    • Calcineurin Regulates Innate Antifungal Immunity in Neutrophils 

      Greenblatt, Matthew Blake; Aliprantis, Antonios O.; Hu, Bella; Glimcher, Laurie Hollis (Rockefeller University Press, 2010)
      Patients taking immunosuppressive drugs, like cyclosporine A (CsA), that inhibit calcineurin are highly susceptible to disseminated fungal infections, although it is unclear how these drugs suppress resistance to these ...
    • Calcium and dairy intakes in relation to long-term weight gain in US men 

      Rajpathak, Swapnil N.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Rosner, Bernard; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Hu, Frank B. (Oxford University Press, 2006)
      Background: The role of calcium in the maintenance of body weight remains controversial. Objective: We investigated the association between calcium and dairy intakes and 12-y weight change in US men. Design: This study was ...
    • Calcium and Vitamin D Intakes in Relation to Risk of Distal Colorectal Adenoma in Women 

      Oh, K.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Wu, K.; Fuchs, C. S.; Giovannucci, E. L. (Oxford University Press, 2007)
      The authors examined intakes of calcium and vitamin D, and interaction with retinol, in relation to risk of adenoma of the distal colon or rectum among 48,115 US women who were free of colorectal cancer or polyps, completed ...
    • Calcium Intake and Risk of Primary Hyperparathyroidism in Women: Prospective Cohort Study 

      Paik, Julie; Curhan, Gary Craig; Taylor, Eric N. (BMJ Publishing Group Ltd., 2012)
      Objective: To examine the association between calcium intake and risk of primary hyperparathyroidism in women. Design Prospective cohort study. Setting Nurses’ Health Study I, which originally recruited participants from ...
    • Calcium Supplement Intake and Risk of Cardiovascular Disease in Women 

      Paik, Julie; Curhan, Gary; Sun, Qi; Rexrode, Kathryn; Manson, JoAnn; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Taylor, Eric (2014)
      Some recent reports suggest that calcium supplement use may increase risk of cardiovascular disease. In a prospective cohort study of 74,245 women in the Nurses' Health Study with 24 years of follow-up, we found no independent ...
    • Calcium, Vitamin D, and Dairy Foods and the Occurrence of Colon Cancer in Men 

      Keamey, J.; Giovannucci, E.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Ascherio, A.; Stampfer, Meir; Colditz, G. A.; Wing, A.; Kampman, E.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600 (Oxford University Press, 1996)