Browsing SPH Scholarly Articles by Title
Now showing items 2801-2820 of 6362
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Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies
(Cold Spring Harbor Laboratory Press, 2004)Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. A small fraction of SNPs (tag SNPs) is sufficient to capture ... -
Haplotype Information and Linkage Disequilibrium Mapping for Single Nucleotide Polymorphisms
(Cold Spring Harbor Laboratory Press, 2003)Single nucleotide polymorphisms in the human genome have become an increasingly popular topic in that their analyses promise to be a key step toward personalized medicine. We investigate two related questions, how much the ... -
Haptoglobin Genotype Is a Consistent Marker of Coronary Heart Disease Risk Among Individuals with Elevated Glycosylated Hemoglobin
(Elsevier, 2013)Objectives This study sought to investigate into the biologically plausible interaction between the common haptoglobin (Hp) polymorphism rs#72294371 and glycosylated hemoglobin (HbA(1c)) on risk of coronary heart disease ... -
Harnessing Poverty Alleviation to Reduce the Stigma of HIV in Sub-Saharan Africa
(Public Library of Science, 2013)Alexander Tsai and colleagues highlight the complex relationship between poverty and HIV stigma in sub-Saharan Africa, and discuss possible ways to break the cycle. Please see later in the article for the Editors' Summary -
Harnessing the diversity of small-scale actors is key to the future of aquatic food systems
(Springer Science and Business Media LLC, 2021-09-15) -
Harnessing the Medicaid Analytic eXtract (MAX) to Evaluate Medications in Pregnancy: Design Considerations
(Public Library of Science, 2013)Background: In the absence of clinical trial data, large post-marketing observational studies are essential to evaluate the safety and effectiveness of medications during pregnancy. We identified a cohort of pregnancies ... -
Has the tobacco industry evaded the FDA's ban on ‘Light’ cigarette descriptors?
(BMJ Publishing Group, 2014)Background: Under the Family Smoking Prevention and Tobacco Control Act (FSPTCA), the Food and Drug Administration (FDA) banned the use of “Lights” descriptors or similar terms on tobacco products that convey messages of ... -
Has the Tobacco Industry Evaded the Intent and Purpose of the FDA's Ban on "Light" Cigarette Descriptors
(BMJ Journals, 2013)Background Under the Family Smoking Prevention and Tobacco Control Act (FSPTCA), the Food and Drug Administration (FDA) banned the use of “Lights” descriptors or similar terms on tobacco products that convey messages of ... -
A hazardous substance exposure prevention rating method for intervention needs assessment and effectiveness evaluation: the Small Business Exposure Index
(BioMed Central, 2009)Aims: This paper describes the refinement and adaptation to small business of a previously developed method for systematically prioritizing needs for intervention on hazardous substance exposures in manufacturing worksites, ... -
HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women
(Springer Verlag, 2008)Aims/hypothesis Diabetes is known to increase mortality rate, but the degree to which mild hyperglycaemia may be associated with the risk of death is uncertain. We examined the association between HbA(1c) measured in stored ... -
HCV-Related Burden of Disease in Europe: A Systematic Assessment of Incidence, Prevalence, Morbidity, and Mortality
(BioMed Central, 2009)Background: Hepatitis C virus (HCV) is a leading cause of chronic liver disease, end-stage cirrhosis, and liver cancer, but little is known about the burden of disease caused by the virus. We summarised burden of disease ... -
HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells
(American Chemical Society, 2014)We examined the effects of isoform-specific histone deacetylase (HDAC) inhibitors on β-catenin posttranslational modifications in neural progenitor cells (NPCs) derived from human induced pluripotent stem cells (iPSCs). ... -
Headache, migraine and risk of brain tumors in women: prospective cohort study
(Springer Milan, 2015)Background: While headache is a common symptom among brain tumors patients, often patients with common headache have concerns of being at risk for developing brain tumors. We aimed to disprove that migraine or headache in ... -
Headache, migraine, and structural brain lesions and function: population based Epidemiology of Vascular Ageing-MRI study
(BMJ Publishing Group Ltd., 2011)Objective: To evaluate the association of overall and specific headaches with volume of white matter hyperintensities, brain infarcts, and cognition. Design: Population based, cross sectional study. Setting: Epidemiology ... -
Health and Economic Burden of Post-Partum Staphylococcus aureus Breast Abscess
(Public Library of Science, 2013)Objectives: To determine the health and economic burdens of post-partum Staphylococcus aureus breast abscess. Study design We conducted a matched cohort study (N = 216) in a population of pregnant women (N = 32,770) who ... -
Health and Economic Impact of Rotavirus Vaccination in GAVI-Eligible Countries
(BioMed Central, 2010)Background: Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately borne by children in low-income countries. Recently the World Health Organization (WHO) has ... -
Health benefits of reduced patient cost sharing in Japan
(, 2012)Objective To assess the effect on out-of-pocket medical spending and physical and mental health of Japan's reduction in health-care cost sharing from 30% to 10% when people turn 70 years of age.Methods Study data came from ... -
Health Care for Immigrants — Implications of Obama's Executive Action
(New England Journal of Medicine (NEJM/MMS), 2015) -
Health Care In The Suburbs: An Analysis Of Suburban Poverty And Health Care Access
(Health Affairs (Project Hope), 2017)There are 16.9 million Americans living in poverty in the suburbs—more than in cities or rural communities. Despite recent increases in suburban poverty, the perception of the suburbs as areas of uniform affluence remains, ... -
Health Care Providers’ Experience with a Protocol for the Identification, Treatment, and Referral of Human-Trafficking Victims
(Informa UK Limited, 2016)Abstract The healthcare setting is thought to be one of the most promising places to identify victims of human trafficking. The present study was designed to relay the experiences of a sample of 10 healthcare providers ...