Now showing items 3330-3349 of 6362

    • Insights into Assessing the Genetics of Endometriosis 

      Rahmioglu, Nilufer; Missmer, Stacey Ann; Montgomery, Grant W.; Zondervan, Krina T. (Current Science Inc., 2012)
      Endometriosis is a complex disease arising from the interplay between multiple genetic and environmental factors. The genetic variants potentially underlying the hereditary component of endometriosis have been widely ...
    • Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study 

      Panoutsopoulou, K; Southam, L; Wrayner, N; Zhai, G; Beazley, C; Thorleifsson, G; Arden, N K; Chapman, K; Deloukas, P; McCaskie, A; Ollier, W E R; Ralston, S H; Spector, T D; Valdes, A M; Wallis, G A; Arden, E; Battley, K; Blackburn, H; Blanco, F J; Bumpstead, S; Cupples, L A; Day-Williams, A G; Dixon, K; Doherty, S A; Esko, T; Evangelou, E; Felson, D; Gomez-Reino, J J; Gwilliam, R; Halldorsson, B V; Hauksson, V B; Ingvarsson, T; Jonsdottir, I; Jonsson, H; Keen, R; Kerkhof, H J M; Kloppenburg, M G; Koller, N; Lakenberg, N; Lane, N E; Metspalu, A; Meulenbelt, I; Nevitt, M C; Parimi, N; Potter, S C; Rego-Perez, I; Riancho, J A; Sherburn, K; Slagboom, P E; Stefansson, K; Styrkarsdottir, U; Sumillera, M; Swift, D; Thorsteinsdottir, U; Tsezou, A; Uitterlinden, A G; van Meurs, J B J; Watkins, B; Zmuda, J M; Zeggini, E; Loughlin, J; Ioannidis, John; Elliot, K S; Carr, A; Doherty, M; Wilkinson, J M; Gonzalez, A; Gordon, A; Hofman, A; Hunt, S E; Lee, A T; Wheeler, M; Mitchell, S; Zhu, Y; O'Neill, F (BMJ Group, 2010)
      Objectives: The genetic aetiology of osteoarthritis has not yet been elucidated. To enable a well-powered genome-wide association study (GWAS) for osteoarthritis, the authors have formed the arcOGEN Consortium, a UK-wide ...
    • Insights into Vibrio cholerae Intestinal Colonization from Monitoring Fluorescently Labeled Bacteria 

      Millet, Yves A.; Alvarez, David; Ringgaard, Simon; von Andrian, Ulrich H.; Davis, Brigid M.; Waldor, Matthew K. (Public Library of Science, 2014)
      Vibrio cholerae, the agent of cholera, is a motile non-invasive pathogen that colonizes the small intestine (SI). Most of our knowledge of the processes required for V. cholerae intestinal colonization is derived from ...
    • Instant Noodle Intake and Dietary Patterns Are Associated with Distinct Cardiometabolic Risk Factors in Korea 

      Shin, H. J.; Cho, E.; Lee, H.-J.; Fung, T. T.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Rosner, B.; Manson, J. E.; Wheelan, K.; Hu, F. B. (Oxford University Press, 2014)
      The consumption of instant noodles is relatively high in Asian populations. It is unclear whether a higher intake of instant noodles is associated with cardiometabolic risk independent of overall dietary patterns. We ...
    • Institutionalizing postpartum intrauterine device (IUD) services in Sri Lanka, Tanzania, and Nepal: study protocol for a cluster-randomized stepped-wedge trial 

      Canning, David; Shah, Iqbal H.; Pearson, Erin; Pradhan, Elina; Karra, Mahesh; Senderowicz, Leigh; Bärnighausen, Till; Spiegelman, Donna; Langer, Ana (BioMed Central, 2016)
      Background: During the year following the birth of a child, 40% of women are estimated to have an unmet need for contraception. The copper IUD provides safe, effective, convenient, and long-term contraceptive protection ...
    • Instrumental variable approaches to identifying the causal effect of educational attainment on dementia risk 

      Nguyen, Thu; Tchetgen, Eric J. Tchetgen; Kawachi, Ichiro; Gilman, Stephen; Walter, Stefan; Liu, Sze; Manly, Jennifer; Glymour, M. Maria (, 2016)
      Purpose: Education is an established correlate of cognitive status in older adulthood, but whether expanding educational opportunities would improve cognitive functioning remains unclear given limitations of prior studies ...
    • Insulin resistance in HIV-infected youth is associated with decreased mitochondrial respiration 

      Takemoto, Jody K.; Miller, Tracie L.; Wang, Jiajia; Jacobson, Denise L.; Geffner, Mitchell E.; Van Dyke, Russell B.; Gerschenson, Mariana (Lippincott Williams & Wilkins, 2016)
      Objective: To identify relationships between insulin resistance (IR) and mitochondrial respiration in perinatally HIV-infected youth. Design: Case–control study. Methods: Mitochondrial respiration was assessed in perinatally ...
    • Insulin resistance, subclinical left ventricular remodeling, and the obesity paradox: the multi-ethnic study of atherosclerosis 

      Shah, Ravi Vikram; Abbasi, Siddique Akbar; Heydari, Bobby; Rickers, Carsten; Jacobs, David R; Wang, Lu; Kwong, Raymond Yan-Kit; Bluemke, David A; Lima, Joao A; Jerosch-Herold, Michael (BioMed Central, 2013)
    • Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia 

      Mantzoros, C. S.; Tzonou, A.; Signorello, L. B.; Stampfer, M.; Trichopoulos, D.; Adami, H-O (Springer Nature, 1997)
    • Insulin-Like Growth Factor Axis and Risk of Type 2 Diabetes in Women 

      Rajpathak, Swapnil N.; He, Meian; Sun, Qi; Kaplan, Robert C.; Muzumdar, Radhika; Rohan, Thomas E.; Gunter, Marc J.; Pollak, Michael; Kim, Mimi; Pessin, Jeffrey E.; Beasley, Jeannette; Wylie-Rosett, Judith; Hu, Frank B.; Strickler, Howard D. (American Diabetes Association, 2012)
      IGF-I shares structural homology and in vitro metabolic activity with insulin. Laboratory models suggest that IGF-I and its binding proteins IGFBP-1 and IGFBP-2 have potentially beneficial effects on diabetes risk, whereas ...
    • Insulin-like Growth Factor Pathway Genetic Polymorphisms, Circulating IGF1 and IGFBP3, and Prostate Cancer Survival 

      Cao, Yin; Lindström, Sara; Schumacher, Fredrick; Stevens, Victoria; Albanes, Demetrius; Berndt, Sonja; Boeing, Heiner; Bueno-de-Mesquita, H. Bas; Canzian, Federico; Chamosa, Saioa; Chanock, Stephen; Diver, W. Ryan; Gapstur, Susan; Gaziano, J. Michael; Giovannucci, Edward; Haiman, Christopher; Henderson, Brian; Johansson, Mattias; Loïc Le Marchand; Palli, Domenico; Rosner, Bernard; Siddiq, Afshan; Stampfer, Meir; Stram, Daniel; Tamimi, Rulla; Travis, Ruth; Trichopoulos, Dimitrios; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Yeager, Meredith; Kraft, Peter; Hsing, Ann; Pollak, Michael; Lin, Xihong; Ma, Jing (Oxford University Press, 2014)
    • Insulin-like Growth Factor Pathway Genetic Polymorphisms, Circulating IGF1 and IGFBP3, and Prostate Cancer Survival 

      Cao, Yin; Lindström, Sara; Schumacher, Fredrick; Stevens, Victoria; Albanes, Demetrius; Berndt, Sonja; Boeing, Heiner; Bueno-de-Mesquita, H. Bas; Canzian, Federico; Chamosa, Saioa; Chanock, Stephen; Diver, W. Ryan; Gapstur, Susan; Gaziano, J. Michael; Giovannucci, Edward; Haiman, Christopher; Henderson, Brian; Johansson, Mattias; Loïc Le Marchand; Palli, Domenico; Rosner, Bernard; Siddiq, Afshan; Stampfer, Meir; Stram, Daniel; Tamimi, Rulla; Travis, Ruth; Trichopoulos, Dimitrios; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Yeager, Meredith; Kraft, Peter; Hsing, Ann; Pollak, Michael; Lin, Xihong; Ma, Jing (Oxford University Press, 2014)
    • Insulin-like growth factor-1, insulin-like growth factor binding protein-3 and lobule type in the Nurses' Health Study II 

      Rice, Megan Siobhan; Tamimi, Rulla May; Connolly, James Leo; Collins, Laura Christine; Shen, Dejun; Pollak, Michael N; Rosner, Bernard Alfred; Hankinson, Susan Elizabeth; Tworoger, Shelley Slate (BioMed Central, 2012)
      Introduction: Previous research in the Nurses' Health Study (NHS) and the NHSII observed that, among women diagnosed with benign breast disease (BBD), those with predominant type 1/no type 3 lobules (a marker of complete ...
    • Insurance Churning Rates For Low-Income Adults Under Health Reform: Lower Than Expected But Still Harmful For Many 

      Sommers, Benjamin Daniel; Gourevitch, Rebecca Anna; Maylone, Bethany Abrams; Blendon, Robert J.; Epstein, Arnold M. (Project HOPE, 2016)
      Changes in insurance coverage over time, or “churning,” may have adverse consequences, but there has been little evidence on churning since implementation of the major coverage expansions in the Affordable Care Act (ACA) ...
    • Insurance Coverage of Emergency Care for Young Adults under Health Reform 

      Mulcahy, Andrew; Harris, Katherine; Finegold, Kenneth; Kellermann, Arthur; Edelman, Laurel; Sommers, Benjamin Daniel (New England Journal of Medicine (NEJM/MMS), 2013)
      Background: The Affordable Care Act (ACA) established nationwide eligibility for young adults 19 to 25 years of age to retain coverage under their parents’ private health plans. We conducted a study to determine how the ...
    • Insurers Again at Odds With Hospitals and Physicians 

      Cutler, David M. (American Medical Association (AMA), 2015)
    • Intake of Alcohol and Alcoholic Beverages and the Risk of Basal Cell Carcinoma of the Skin 

      Fung, Teresa; Hunter, David; Spiegelman, Donna; Colditz, Graham; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600 (American Association for Cancer Research, 2002)
      We prospectively examined the intake of alcoholic beverages in relation to the risk of basal cell carcinoma BCC in two large cohorts of men and women. Alcohol intake was assessed with food frequency questionnaires every ...
    • Intake of antioxidant vitamins and risk of Parkinson's disease 

      Hughes, Katherine; Gao, Xiang; Kim, Iris; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Wang, Molin; Weisskopf, Marc; Schwarzschild, Michael; Ascherio, Alberto (2016)
      Introduction: Oxidative stress is proposed to be one of the potential mechanisms leading to neurodegeneration in Parkinson's disease. However, previous epidemiologic studies investigating associations between antioxidant ...
    • Intake of Caffeinated, Carbonated, or Citrus Beverage Types and Development of Lower Urinary Tract Symptoms in Men and Women 

      Maserejian, Nancy N.; Wager, Carrie G.; Giovannucci, Edward L.; Curto, Teresa M.; McVary, Kevin T.; McKinlay, John B. (Oxford University Press, 2013)
      Evidence to substantiate recommendations for restriction of caffeinated or acidic beverages as self-management for lower urinary tract symptoms (LUTS) is limited. We examined longitudinal and acute associations between ...
    • Intake of dietary flavonoids and risk of epithelial ovarian cancer1234 

      Cassidy, Aedín; Huang, Tianyi; Rice, Megan S; Rimm, Eric B; Tworoger, Shelley S (American Society for Nutrition, 2014)
      Background: The impact of different dietary flavonoid subclasses on risk of epithelial ovarian cancer is unclear, with limited previous studies that have focused on only a few compounds. Objective: We prospectively examined ...