Now showing items 5206-5225 of 6362

    • Religious service attendance and lower depression among women - a prospective cohort study 

      Li, Shanshan; Okereke, Olivia; Chang, Shun-Chiao; Kawachi, Ichiro; VanderWeele, Tyler (, 2016)
      Previous studies on the association between religious service attendance and depression have been mostly cross-sectional, subject to reverse causation, and did not account for the potential feedback between religious service ...
    • Remote video auditing with real-time feedback in an academic surgical suite improves safety and efficiency metrics: a cluster randomised study 

      Overdyk, Frank J; Dowling, Oonagh; Newman, Sheldon; Glatt, David; Chester, Michelle; Armellino, Donna; Cole, Brandon; Landis, Gregg S; Schoenfeld, David; DiCapua, John F (BMJ Publishing Group, 2016)
      Importance Compliance with the surgical safety checklist during operative procedures has been shown to reduce inhospital mortality and complications but proper execution by the surgical team remains elusive. Objective: We ...
    • Removing the blindfold on medicines pricing 

      Moon, Suerie (BMJ, 2018)
      Tisagenlecleucel (Kymriah), one of several promising chimeric antigen receptor T cell (CAR-T) therapies, is the first gene therapy to get US approval. Novartis announced in September 2017 that the leukaemia treatment would ...
    • Renal Function Following Three Distinct Weight Loss Dietary Strategies During 2 Years of a Randomized Controlled Trial 

      Tirosh, Amir; Golan, Rachel; Harman-Boehm, Ilana; Henkin, Yaakov; Schwarzfuchs, Dan; Rudich, Assaf; Kovsan, Julia; Fiedler, Georg M.; Blüher, Matthias; Stumvoll, Michael; Thiery, Joachim; Stampfer, Meir J.; Shai, Iris (American Diabetes Association, 2013)
      OBJECTIVE This study addressed the long-term effect of various diets, particularly low-carbohydrate high-protein, on renal function on participants with or without type 2 diabetes. RESEARCH DESIGN AND METHODS In the 2-year ...
    • Reorientation of aquaculture production systems can reduce environmental impacts and improve nutrition security in Bangladesh 

      Shepon, Alon; Gephart, Jessica A.; Henriksson, Patrik John Gustav; Jones, Robert; Murshed-e-Jahan, Khondker; Eshel, Gidon; Golden, Christopher (Springer Science and Business Media LLC, 2020-10)
      Aquatic foods are a critical source of human nutrition in many developing countries. As a result, declines in wild-caught fish landings threaten nutritionally vulnerable populations. Aquaculture presents an opportunity to ...
    • Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients12 

      Jafari-Khouzani, Kourosh; Emblem, Kyrre E.; Kalpathy-Cramer, Jayashree; Bjørnerud, Atle; Vangel, Mark G.; Gerstner, Elizabeth R.; Schmainda, Kathleen M.; Paynabar, Kamran; Wu, Ona; Wen, Patrick Y.; Batchelor, Tracy; Rosen, Bruce; Stufflebeam, Steven M. (Neoplasia Press, 2015)
      OBJECTIVES This study evaluates the repeatability of brain perfusion using dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) with a variety of post-processing methods. METHODS Thirty-two patients with ...
    • Repeated Mouse Lung Exposures to Stachybotrys chartarum Shift Immune Response from Type 1 to Type 2 

      Rosenblum Lichtenstein, Jamie H.; Hsu, Yi-Hsiang H.; Mathews, Joel A.; Park, Jin-Ah; Bordini, André; Gillis, Bruce S.; Brain, Joseph; Molina, Ramon; Donaghey, Thomas; Kasahara, David; Godleski, John (American Thoracic Society, 2016-10)
      After a single or multiple intratracheal instillations of Stachybotrys chartarum (S. chartarum or black mold) spores in BALB/c mice, we characterized cytokine production, metabolites, and inflammatory patterns by analyzing ...
    • Replication of five prostate cancer loci identified in an Asian population – Results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3) 

      Lindstrom, Sara; Schumacher, Fredrick R.; Campa, Daniele; Albanes, Demetrius; Andriole, Gerald; Berndt, Sonja I.; Bueno-de-Mesquita, H. Bas; Chanock, Stephen J.; Diver, W. Ryan; Ganziano, J. Michael; Gapstur, Susan M.; Giovannucci, Edward; Haiman, Christopher A.; Henderson, Brian; Hunter, David J.; Johansson, Mattias; Kolonel, Laurence N.; Marchand, Loic Le; Ma, Jing; Stampfer, Meir; Stevens, Victoria L.; Trichopoulos, Dimitrios; Virtamo, Jarmo; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Yeager, Meredith; Hsing, Ann W.; Kraft, Peter (American Association for Cancer Research, 2012)
      Background: A recent genome-wide association study (GWAS) of prostate cancer in a Japanese population identified five novel regions not previously discovered in other ethnicities. In this study, we attempt to replicate ...
    • Replication of Functional Serotonin Receptor Type 3A and B Variants in Bipolar Affective Disorder: A European Multicenter Study 

      Hammer, C; Cichon, S; Mühleisen, T W; Haenisch, B; Degenhardt, F; Breuer, R; Witt, S H; Strohmaier, J; Oruc, L; Rivas, F; Babadjanova, G; Grigoroiu-Serbanescu, M; Röth, R; Rappold, G; Rietschel, M; Nöthen, M M; Niesler, B; Mattheisen, Manuel; Hauser, J (Nature Publishing Group, 2012)
      Serotonin type 3 receptors (\(5-HT_3\)) are involved in learning, cognition and emotion, and have been implicated in various psychiatric phenotypes. However, their contribution to the pathomechanism of these disorders ...
    • Replicative Capacity Differences of Thymidine Analog Resistance Mutations in Subtype B and C Human Immunodeficiency Virus Type 1 

      Armstrong, K. L.; Lee, T.-H.; Essex, Myron Elmer (American Society for Microbiology, 2009)
      In order to understand the impact of zidovudine resistance and thymidine analog mutations (TAMs) on subtype C human immunodeficiency virus type 1, we created mutants in subtype C reverse transcriptase (RT). The subtype B ...
    • Replicative Fitness Costs of Nonnucleoside Reverse Transcriptase Inhibitor Drug Resistance Mutations on HIV Subtype C 

      Armstrong, Katherine Leebner; Lee, Tae Ho; Essex, Myron Elmer (American Society for Microbiology, 2011)
      Single-dose nevirapine (NVP) is quite effective in preventing transmission of the human immunodeficiency virus (HIV) from mother to child; however, many women develop resistance to NVP in this setting. Comparing outcomes ...
    • Report on emerging technologies for translational bioinformatics: a symposium on gene expression profiling for archival tissues 

      Waldron, Levi D.; Simpson, Peter; Parmigiani, Giovanni; Huttenhower, Curtis (BioMed Central, 2012)
      Background: With over 20 million formalin-fixed, paraffin-embedded (FFPE) tissue samples archived each year in the United States alone, archival tissues remain a vast and under-utilized resource in the genomic study of ...
    • Reporting of Aspiration Pneumonia or Choking as a Cause of Death in Patients Who Died with Stroke 

      Chang, C.-Y.; Cheng, T.-J.; Lin, C.-Y.; Chen, J.-Y.; Lu, T.-H.; Kawachi, I. (2013)
      Background and Purpose-It is not known how many stroke patients die from fatal pulmonary complications such as aspiration pneumonia (AP) and choking each year in the United States. This study aimed to determine the frequency ...
    • Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia 

      Reynolds, Christine; Roderick, Justine E.; LaBelle, James L.; Bird, Gregory; Mathieu, Ronald; Bodaar, Kimberly; Colon, Diana; Pyati, Ujwal; Stevenson, Kristen E.; Qi, Jun; Harris, Marian; Silverman, Lewis B.; Sallan, Stephen E.; Bradner, James E.; Neuberg, Donna S.; Look, A. Thomas; Walensky, Loren D.; Kelliher, Michelle A.; Gutierrez, Alejandro (2014)
      Treatment resistance in T-cell acute lymphoblastic leukemia (T-ALL) is associated with PTEN deletions and resultant PI3K-AKT pathway activation, as well as MYC overexpression, and these pathways repress mitochondrial ...
    • Reproducibility and validity of dietary patterns assessed with a food-frequency questionnaire 

      Hu, Frank B.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Smith-Warner, Stephanie A.; Feskanich, Diane; Stampfer, Meir; Ascherio, Albert; Sampson, Laura; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600 (Oxford University Press, 1999)
      Background: Recently, the analysis of dietary patterns has emerged as a possible approach to examining diet-disease relations. Objective: We examined the reproducibility and validity of dietary patterns defined by factor ...
    • Reproducibility and validity of the Diet Quality Index Revised as assessed by use of a food-frequency questionnaire 

      Newby, P. K.; Hu, Frank B.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Smith-Warner, Stephanie A.; Feskanich, Diane; Sampson, Laura; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600 (Oxford University Press, 2003)
      Background: The Diet Quality Index Revised (DQI-R) is a dietary assessment instrument based on 10 dietary recommendations reflecting dietary guidelines and policy in the United States. Objective: The objective of this study ...
    • The Reproducibility of a Method to Identify the Overuse and Underuse of Medical Procedures 

      Shekelle, Paul G.; Kahan, James P.; Bernstein, Steven J.; Leape, Lucian; Kamberg, Caren J.; Park, R.E. (Massachusetts Medical Society, 1998-06-25)
      BACKGROUND To assess the overuse and underuse of medical procedures, various methods have been developed, but their reproducibility has not been evaluated. This study estimates the reproducibility of one commonly used ...
    • Reproducibility of Circulating MicroRNAs in Stored Plasma Samples 

      Bertoia, Monica; Bertrand, Kimberly Anne; Sawyer, Sherilyn; Rimm, Eric Bruce; Mukamal, Kenneth J. (Public Library of Science (PLoS), 2015)
      Background Most studies of microRNA (miRNA) and disease have examined tissue-specific expression in limited numbers of samples. The presence of circulating miRNAs in plasma samples provides the opportunity to examine ...
    • A reproducible approach to high-throughput biological data acquisition and integration 

      Börnigen, Daniela; Moon, Yo Sup; Rahnavard, Gholamali; Waldron, Levi; McIver, Lauren; Shafquat, Afrah; Franzosa, Eric A.; Miropolsky, Larissa; Sweeney, Christopher; Morgan, Xochitl C.; Garrett, Wendy S.; Huttenhower, Curtis (PeerJ Inc., 2015)
      Modern biological research requires rapid, complex, and reproducible integration of multiple experimental results generated both internally and externally (e.g., from public repositories). Although large systematic ...
    • Reproductive aging-associated common genetic variants and the risk of breast cancer 

      He, Chunyan; Chasman, Daniel Ian; Dreyfus, Jill; Hwang, Shih-Jen; Ruiter, Rikje; Sanna, Sanna; Buring, Julie Elizabeth; Fernández-Rhodes, Lindsay; Franceschini, Nora; Hankinson, Susan Elizabeth; Hofman, Albert; Lunetta, Kathryn L.; Palmieri, Giuseppe; Porcu, Eleonora; Rivadeneira, Fernando; Rose, Lynda M.; Splansky, Greta L.; Stolk, Lisette; Uitterlinden, André G.; Chanock, Stephen J.; Crisponi, Laura; Demerath, Ellen W.; Murabito, Joanne M.; Ridker, Paul M.; Stricker, Bruno H.; Hunter, David J. (BioMed Central, 2011)
      Introduction: A younger age at menarche and an older age at menopause are well established risk factors for breast cancer. Recent genome-wide association studies have identified several novel genetic loci associated with ...