Browsing SPH Scholarly Articles by Keyword "ACPA"

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High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis

Gomez-Cabrero, David; Almgren, Malin; Sjöholm, Louise K.; Hensvold, Aase H.; Ringh, Mikael V.; Tryggvadottir, Rakel; Kere, Juha; Scheynius, Annika; Acevedo, Nathalie; Reinius, Lovisa; Taub, Margaret A.; Montano, Carolina; Aryee, Martin J.; Feinberg, Jason I.; Feinberg, Andrew P.; Tegnér, Jesper; Klareskog, Lars; Catrina, Anca I.; Ekström, Tomas J. (BioMed Central, 2016)

Background: Twin studies are powerful models to elucidate epigenetic modifications resulting from gene–environment interactions. Yet, commonly a limited number of clinical twin samples are available, leading to an underpowered ...