Browsing SPH Scholarly Articles by Keyword "Haplotype"

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    • Determinants of host susceptibility to murine respiratory syncytial virus (RSV) disease identify a role for the innate immunity scavenger receptor MARCO gene in human infants 

      High, Monica; Cho, Hye-Youn; Marzec, Jacqui; Wiltshire, Tim; Verhein, Kirsten C.; Caballero, Mauricio T.; Acosta, Patricio L.; Ciencewicki, Jonathan; McCaw, Zackary R.; Kobzik, Lester; Miller-DeGraff, Laura; Gladwell, Wes; Peden, David B.; Serra, M. Elina; Shi, Min; Weinberg, Clarice; Suzuki, Oscar; Wang, Xuting; Bell, Douglas A.; Polack, Fernando P.; Kleeberger, Steven R. (Elsevier, 2016)
      Background: Respiratory syncytial virus (RSV) is the global leading cause of lower respiratory tract infection in infants. Nearly 30% of all infected infants develop severe disease including bronchiolitis, but susceptibility ...

    • A genome-wide survey of CD4+ lymphocyte regulatory genetic variants identifies novel asthma genes 

      Sharma, Sunita; Zhou, Xiaobo; Thibault, Derek M.; Himes, Blanca; Liu, Andy; Szefler, Stanley J.; Strunk, Robert; Castro, Mario; Hansel, Nadia N.; Diette, Gregory B.; Vonakis, Becky M.; Adkinson, N. Franklin; Avila, Lydiana; Soto-Quiros, Manuel; Barraza-Villareal, Albino; Lemanske, Robert F.; Solway, Julian; Krishnan, Jerry; White, Steven James; Cheadle, Chris; Berger, Alan E.; Fan, Jinshui; Boorgula, Meher Preethi; Nicolae, Dan; Gilliland, Frank; Barnes, Kathleen; London, Stephanie J.; Martinez, Fernando; Ober, Carole; Celedón, Juan C.; Carey, Vincent James; Weiss, Scott Tillman; Raby, Benjamin Alexander (Elsevier BV, 2014)
      Background: Genome-wide association studies have yet to identify the majority of genetic variants involved in asthma. We hypothesized that expression quantitative trait locus (eQTL) mapping can identify novel asthma genes ...