Now showing items 1-20 of 36

    • Accumulation of Metabolic Cardiovascular Risk Factors in Black and White Young Adults Over 20 Years 

      Paynter, Nina P.; Kiefe, Catarina I.; Lewis, Cora E.; Loria, Catherine M.; Goff, David C.; Lloyd‐Jones, Donald M. (Blackwell Publishing Ltd, 2015)
      Background: Cross‐sectional clustering of metabolic risk factors for cardiovascular disease in middle‐aged adults is well described, but less is known regarding the order in which risk factors develop through young adulthood ...
    • Adherence to the Mediterranean diet and body fat distribution in reproductive aged women 

      Boghossian, Nansi S.; Yeung, Edwina H.; Mumford, Sunni L.; Zhang, Cuilin; Gaskins, Audrey J.; Wactawski-Wende, Jean; Schisterman, Enrique F. (2013)
      Background/Objectives Adherence to the Mediterranean Diet (MD) high in fruits, vegetables and monounsaturated fats, has been associated with lower body mass index. Associations with measured body fat, including regional ...
    • Association of body mass index and waist circumference with successful ageing: 16 year follow-up of the Whitehall II study 

      Singh-Manoux, Archana; Sabia, Séverine; Bouillon, Kim; Brunner, Eric J; Grodstein, Francine; Elbaz, Alexis; Kivimaki, Mika (2013)
      Objective: We examined whether midlife body mass index (BMI) and waist circumference (WC) predict successful ageing. Design and Methods BMI/WC were assessed in 4869 persons (mean age 51.2, range 42–63 in 1991/93) and ...
    • Bicycling to Work and Primordial Prevention of Cardiovascular Risk: A Cohort Study Among Swedish Men and Women 

      Grøntved, Anders; Koivula, Robert W.; Johansson, Ingegerd; Wennberg, Patrik; Østergaard, Lars; Hallmans, Göran; Renström, Frida; Franks, Paul W. (John Wiley and Sons Inc., 2016)
      Background: Bicycling to work may be a viable approach for achieving physical activity that provides cardiovascular health benefits. In this study we investigated the relationship of bicycling to work with incidence of ...
    • A Brief Targeted Review of Susceptibility Factors, Environmental Exposures, Asthma Incidence, and Recommendations for Future Asthma Incidence Research 

      Yeatts, Karin; Sly, Peter; Martinez, Fernando; Geller, Andrew; Bromberg, Philip; Enright, Paul; Koren, Hillel; Weissman, David; Selgrade, MaryJane; Shore, Stephanie; Weiss, Scott Tillman (National Institute of Environmental Health Sciences, 2006)
      Relative to research on effects of environmental exposures on exacerbation of existing asthma, little research on incident asthma and environmental exposures has been conducted. However, this research is needed to better ...
    • Chronic Insufficient Sleep and Diet Quality: Contributors to Childhood Obesity 

      Cespedes, Elizabeth M.; Hu, Frank B.; Redline, Susan; Rosner, Bernard; Gillman, Matthew W.; Rifas-Shiman, Sheryl L.; Taveras, Elsie M. (2015)
      Objective: To examine associations of chronic insufficient sleep with diet, and whether diet explains the sleep-adiposity relationship. Methods: In Project Viva, 1,046 parents reported children’s sleep duration at 6m and ...
    • Developmental origins of adult diseases and neurotoxicity: Epidemiological and experimental studies 

      Fox, Donald A.; Grandjean, Philippe; de Groot, Didima; Paule, Merle G. (Elsevier BV, 2012)
      To date, only a small number of commercial chemicals have been tested and documented as developmental neurotoxicants. Moreover, an increasing number of epidemiological, clinical and experimental studies suggest an association ...
    • Does Diet Affect Breast Cancer Risk? 

      Holmes, Michelle D.; Willett, Walter C. (BioMed Central, 2004)
      The role of specific dietary factors in breast cancer causation is not completely resolved. Results from prospective studies do not support the concept that fat intake in middle life has a major relation to breast cancer ...
    • Early Pregnancy Maternal Hepatocyte Growth Factor and Risk of Gestational Diabetes 

      Dishi, Michal; Hevner, Karin; Qiu, Chunfang; Fida, Neway G.; Abetew, Dejene F.; Williams, Michelle A.; Enquobahrie, Daniel A. (2016)
      Aims We investigated associations of serum hepatocyte growth factor (HGF) with risk of gestational diabetes mellitus (GDM). We also examined whether pre-pregnancy overweight/obesity status or leisure-time physical activity ...
    • Environment and Obesity in the National Children's Study 

      Trasande, Leonardo; Cronk, Chris; Durkin, Maureen; Weiss, Marianne; Schoeller, Dale A.; Gall, Elizabeth A.; Hewitt, Jeanne B.; Carrel, Aaron L.; Landrigan, Philip J.; Gillman, Matthew William (National Institute of Environmental Health Sciences, 2008)
      Objective: In this review we describe the approach taken by the National Children’s Study (NCS), a 21-year prospective study of 100,000 American children, to understanding the role of environmental factors in the development ...
    • Exploring Innovative Approaches and Patient-Centered Outcomes From Positive Outliers in Childhood Obesity 

      Sharifi, Mona; Marshall, Gareth; Goldman, Roberta E.; Rifas-Shiman, Sheryl Lynn; Horan, Christine M.; Koziol, Renata; Marshall, Richard E.; Sequist, Thomas Dean; Taveras, Elsie Mireya (Elsevier BV, 2014)
      Objective New approaches for obesity prevention and management can be gleaned from 'positive outliers', i.e., individuals who have succeeded in changing health behaviors and reducing their body mass index (BMI) in the ...
    • Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution 

      Lindgren, Cecilia M.; Heid, Iris M.; Randall, Joshua C.; Lamina, Claudia; Steinthorsdottir, Valgerdur; Speliotes, Elizabeth K.; Thorleifsson, Gudmar; Willer, Cristen J.; Herrera, Blanca M.; Jackson, Anne U.; Lim, Noha; Scheet, Paul; Soranzo, Nicole; Amin, Najaf; Aulchenko, Yurii S.; Chambers, John C.; Drong, Alexander; Luan, Jian'an; Rivadeneira, Fernando; Sanna, Serena; Timpson, Nicholas J.; Zillikens, M. Carola; Almgren, Peter; Bandinelli, Stefania; Bennett, Amanda J.; Bergman, Richard N.; Bonnycastle, Lori L.; Bumpstead, Suzannah J.; Chanock, Stephen J.; Cherkas, Lynn; Chines, Peter; Coin, Lachlan; Cooper, Cyrus; Crawford, Gabriel; Doering, Angela; Dominiczak, Anna; Doney, Alex S. F.; Ebrahim, Shah; Elliott, Paul; Erdos, Michael R.; Estrada, Karol; Ferrucci, Luigi; Fischer, Guido; Forouhi, Nita G.; Gieger, Christian; Grallert, Harald; Groves, Christopher J.; Grundy, Scott; Guiducci, Candace; Hadley, David; Hamsten, Anders; Havulinna, Aki S.; Holle, Rolf; Holloway, John W.; Illig, Thomas; Isomaa, Bo; Jacobs, Leonie C.; Jameson, Karen; Jousilahti, Pekka; Karpe, Fredrik; Kuusisto, Johanna; Laitinen, Jaana; Lathrop, G. Mark; Lawlor, Debbie A.; Mangino, Massimo; McArdle, Wendy L.; Meitinger, Thomas; Morken, Mario A.; Morris, Andrew P.; Munroe, Patricia; Narisu, Narisu; Nordström, Anna; Nordström, Peter; Oostra, Ben A.; Palmer, Colin N. A.; Payne, Felicity; Peden, John F.; Prokopenko, Inga; Renström, Frida; Ruokonen, Aimo; Salomaa, Veikko; Sandhu, Manjinder S.; Scuteri, Angelo; Silander, Kaisa; Song, Kijoung; Stringham, Heather M.; Swift, Amy J.; Tuomi, Tiinamaija; Uda, Manuela; Vollenweider, Peter; Waeber, Gerard; Wallace, Chris; Walters, G. Bragi; Weedon, Michael N.; Witteman, Jacqueline C. M.; Zhang, Cuilin; Zhang, Weihua; Caulfield, Mark J.; Collins, Francis S.; Davey Smith, George; Day, Ian N. M.; Franks, Paul W.; Hattersley, Andrew T.; Jarvelin, Marjo-Riitta; Kong, Augustine; Kooner, Jaspal S.; Laakso, Markku; Lakatta, Edward; Mooser, Vincent; Morris, Andrew D.; Peltonen, Leena; Samani, Nilesh J.; Spector, Timothy D.; Strachan, David P.; Tanaka, Toshiko; Tuomilehto, Jaakko; Uitterlinden, André G.; van Duijn, Cornelia M.; Wareham, Nicholas J.; Waterworth, Dawn M.; Boehnke, Michael; Deloukas, Panos; Groop, Leif; Thorsteinsdottir, Unnur; Schlessinger, David; Wichmann, H.-Erich; Frayling, Timothy M.; Abecasis, Gonçalo R.; Loos, Ruth J. F.; Stefansson, Kari; Mohlke, Karen L.; Barroso, Inês; Hirschhorn, Joel Naom; McCarthy, Mark I.; Watkins, Hugh; The Wellcome Trust Case Control Consortium; Hunter, David J.; Hu, Frank B.; Yuan, Xin; Scott, Laura J.; Hofman, Albert; Zhao, Jing Hua; Lyon, Helen N; Qi, Lu (Public Library of Science, 2009)
      To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist–hip ...
    • Genotype vs. Phenotype and the Rise of Non-Communicable Diseases: The Importance of Lifestyle Behaviors During Childhood 

      Wu, Brian W; Skidmore, Paula M; Orta, Olivia R; Faulkner, James; Lambrick, Danielle; Signal, Leigh; Williams, Michelle A; Stoner, Lee (Cureus, 2016)
      Despite continued research and growing public awareness, the incidence of non-communicable diseases (NCD) continues to accelerate. While a person may have a genetic predisposition to certain NCDs, the rapidly changing ...
    • Global Burden of Double Malnutrition: Has Anyone Seen It? 

      Corsi, Daniel J.; Finlay, Jocelyn E.; Subramanian, S. V. (Public Library of Science, 2011)
      Background. Low- to middle-income countries (LMICs) are believed to be characterized by the coexistence of underweight and overweight. It has also been posited that such coexistence is appearing among the low socioeconomic ...
    • Glutathione S-Transferase Polymorphisms, Passive Smoking, Obesity, and Heart Rate Variability in Nonsmokers 

      Probst-Hensch, Nicole M.; Imboden, Medea; Dietrich, Denise Felber; Barthélemy, Jean-Claude; Ackermann-Liebrich, Ursula; Berger, Wolfgang; Gaspoz, Jean-Michel; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2008)
      Background: Disturbances of heart rate variability (HRV) may represent one pathway by which second-hand smoke (SHS) and air pollutants affect cardiovascular morbidity and mortality. The mechanisms are poorly understood. ...
    • IL-17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity 

      Kim, Hye Young; Lee, Hyun Jun; Chang, Ya-Jen; Pichavant, Muriel; Shore, Stephanie A.; Fitzgerald, Katherine A.; Iwakura, Yoichiro; Israel, Elliot; Bolger, Kenneth; Faul, John; DeKruyff, Rosemarie H.; Umetsu, Dale T. (2014)
      Obesity is associated with the development of asthma and considerable asthma-related healthcare utilization. To understand the immunological pathways that lead to obesity-associated asthma, we fed mice a high fat diet for ...
    • Information Technology and Lifestyle: A Systematic Evaluation of Internet and Mobile Interventions for Improving Diet, Physical Activity, Obesity, Tobacco, and Alcohol Use 

      Afshin, Ashkan; Babalola, Damilola; Mclean, Mireille; Yu, Zhi; Ma, Wenjie; Chen, Cheng‐Yu; Arabi, Mandana; Mozaffarian, Dariush (John Wiley and Sons Inc., 2016)
      Background: Novel interventions are needed to improve lifestyle and prevent noncommunicable diseases, the leading cause of death and disability globally. This study aimed to systematically review, synthesize, and grade ...
    • Myocardial Tissue Remodeling in Adolescent Obesity 

      Shah, Ravi V.; Abbasi, Siddique A.; Neilan, Tomas G.; Hulten, Edward; Coelho‐Filho, Otavio; Hoppin, Alison; Levitsky, Lynne; de Ferranti, Sarah; Rhodes, Erinn T.; Traum, Avram; Goodman, Elizabeth; Feng, Henry; Heydari, Bobak; Harris, William S.; Hoefner, Daniel M.; McConnell, Joseph P.; Seethamraju, Ravi; Rickers, Carsten; Kwong, Raymond Y.; Jerosch‐Herold, Michael (Blackwell Publishing Ltd, 2013)
      Background: Childhood obesity is a significant risk factor for cardiovascular disease in adulthood. Although ventricular remodeling has been reported in obese youth, early tissue‐level markers within the myocardium that ...
    • Obesity & Hypertension are Determinants of Poor Hemodynamic Control during Total Joint Arthroplasty: A Retrospective Review 

      Nwachukwu, Benedict Uchenna; Collins, Jamie E; Nelson, Emily P; Concepcion, Mercedes; Thornhill, Thomas Stone; Katz, Jeffrey Neil (BioMed Central, 2013)
      Background: Proper blood pressure control during surgical procedures such as total joint arthroplasty (TJA) is considered critical to good outcome. There is poor understanding of the pre-operative risk factors for poor ...
    • Obesity is a modifier of autonomic cardiac responses to fine metal particulates 

      Chen, Jiu-Chiuan; Cavallari, Jennifer Margaret; Stone, Peter Howard; Christiani, David C. (National Institute of Environmental Health Sciences, 2007)
      Background: Increasing evidence suggests that obesity may impart greater susceptibility to adverse effects of air pollution. Particulate matter, especially PM\(_{2.5}\) (particulate matter with aero-dynamic diameter ≤2.5 ...