Browsing SPH Scholarly Articles by Keyword "schizophrenia"

Now showing items 1-5 of 5

    • Deficient biological motion perception in schizophrenia: results from a motion noise paradigm 

      Kim, Jejoong; Norton, Daniel; McBain, Ryan; Ongur, Dost; Chen, Yue (Frontiers Media S.A., 2013)
      Background:: Schizophrenia patients exhibit deficient processing of perceptual and cognitive information. However, it is not well-understood how basic perceptual deficits contribute to higher level cognitive problems in ...

    • Evidence of Common Genetic Overlap Between Schizophrenia and Cognition 

      Hubbard, Leon; Tansey, Katherine E.; Rai, Dheeraj; Jones, Peter; Ripke, Stephan; Chambert, Kimberly D.; Moran, Jennifer L.; McCarroll, Steven A.; Linden, David E. J.; Owen, Michael J.; O’Donovan, Michael C.; Walters, James T. R.; Zammit, Stanley (Oxford University Press, 2015)
      Cognitive impairment is a core feature of schizophrenia but there is limited understanding of the genetic relationship between cognition in the general population and schizophrenia. We examine how common variants associated ...

    • Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof-of-concept and roadmap for future studies 

      Franke, Barbara; Stein, Jason L; Ripke, Stephan; Anttila, Verneri; Hibar, Derrek P; van Hulzen, Kimm J E; Arias-Vasquez, Alejandro; Smoller, Jordan W; Nichols, Thomas E; Neale, Michael C; McIntosh, Andrew M; Lee, Phil; McMahon, Francis J; Meyer-Lindenberg, Andreas; Mattheisen, Manuel; Andreassen, Ole A; Gruber, Oliver; Sachdev, Perminder S; Roiz-Santiañez, Roberto; Saykin, Andrew J; Ehrlich, Stefan; Mather, Karen A; Turner, Jessica A; Schwarz, Emanuel; Thalamuthu, Anbupalam; Shugart, Yin Yao; Ho, Yvonne YW; Martin, Nicholas G; Wright, Margaret J; O'Donovan, Michael C; Thompson, Paul M; Neale, Benjamin M; Medland, Sarah E; Sullivan, Patrick F (2016)
      Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and function differ, on average, between schizophrenia cases and healthy individuals. As common genetic associations are emerging ...

    • Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases 

      Pouget, Jennie G.; Gonçalves, Vanessa F.; Spain, Sarah L.; Finucane, Hilary K.; Raychaudhuri, Soumya; Kennedy, James L.; Knight, Jo (Oxford University Press, 2016)
      There has been intense debate over the immunological basis of schizophrenia, and the potential utility of adjunct immunotherapies. The major histocompatibility complex is consistently the most powerful region of association ...

    • Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives 

      Manoach, Dara S.; Demanuele, Charmaine; Wamsley, Erin J.; Vangel, Mark; Montrose, Debra M.; Miewald, Jean; Kupfer, David; Buysse, Daniel; Stickgold, Robert; Keshavan, Matcheri S. (Frontiers Media S.A., 2014)
      Introduction: Chronic medicated patients with schizophrenia have marked reductions in sleep spindle activity and a correlated deficit in sleep-dependent memory consolidation. Using archival data, we investigated whether ...