Now showing items 1-4 of 4

    • Chemoprevention of cancer: current evidence and future prospects 

      Benetou, Vassiliki; Lagiou, Areti; Lagiou, Pagona (F1000Research, 2015)
      Cancer chemoprevention refers to the use of agents for the inhibition, delay, or reversal of carcinogenesis before invasion. In the present review, agents examined in the context of cancer chemoprevention are classified ...
    • Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag 

      Brumme, Zabrina L.; Rousseau, Christine M.; Brumme, Chanson J.; Matthews, Philippa; Kadie, Carl; Mullins, James I.; Harrigan, P. Richard; Heckerman, David; Carlson, Jonathan M.; Walker, Bruce David; Goulder, Philip J. (Public Library of Science, 2008)
      HIV avoids elimination by cytotoxic T-lymphocytes (CTLs) through the evolution of escape mutations. Although there is mounting evidence that these escape pathways are broadly consistent among individuals with similar human ...
    • Recognition of HIV-1 Peptides by Host CTL Is Related to HIV-1 Similarity to Human Proteins 

      Rolland, Morgane; Nickle, David C.; Deng, Wenjie; Frahm, Nicole; Learn, Gerald H.; Heckerman, David; Jojic, Nebosja; Jojic, Vladimir; Mullins, James I.; Brander, Christian; Walker, Bruce David (Public Library of Science, 2007)
      Background: While human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes preferentially target specific regions of the viral proteome, HIV-1 features that contribute to immune recognition are not well ...
    • Reduced Antibody Responses to Vaccinations in Children Exposed to Polychlorinated Biphenyls 

      Heilmann, Carsten; Grandjean, Philippe; Weihe, Pál; Nielsen, Flemming; Budtz-Jørgensen, Esben (Public Library of Science, 2006)
      Background: Developmental exposure to polychlorinated biphenyls (PCBs) has been implicated as a possible cause of deficient immune function in children. This study was designed to assess whether prenatal and postnatal ...