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Effect of Calcium Supplementation on Blood Lead Levels in Pregnancy: A Randomized Placebo-Controlled Trial
(National Institute of Environmental Health Sciences, 2008)
Background: Prenatal lead exposure is associated with deficits in fetal growth and neurodevelopment. Calcium supplementation may attenuate fetal exposure by inhibiting mobilization of maternal bone lead and/or intestinal ...
Fetal Lead Exposure at Each Stage of Pregnancy as a Predictor of Infant Mental Development
(National Institute of Environmental Health Sciences, 2006)
Background: The impact of prenatal lead exposure on neurodevelopment remains unclear in terms of consistency, the trimester of greatest vulnerability, and the best method for estimating fetal lead exposure. Objective: We ...
Effect of breast milk lead on infant blood lead levels at 1 month of age
(National Institue of Environmental Health Sciences, 2004)
Nursing infants may be exposed to lead from breast milk, but relatively few data exist with which to evaluate and quantify this relationship. This route of exposure constitutes a potential infant hazard from mothers with ...
Variants in iron metabolism genes predict higher blood lead levels in young children
(National Institute of Environmental Health Sciences, 2008)
Background: Given the association between iron deficiency and lead absorption, we hypothesized that variants in iron metabolism genes would predict higher blood lead levels in young children. Objective: We examined the ...
Lead Exposure and Behavior Among Young Children in Chennai, India
(National Institute of Environmental Health Sciences, 2009)
Background: Lead exposure has long been associated with deficits in IQ among children. However, few studies have assessed the impact of lead on specific domains of behavior and cognition. Objective: We evaluated the ...
Maternal arsenic exposure and impaired glucose tolerance during pregnancy
(National Institute of Environmental Health Sciences, 2009)
Background: Accumulating evidence has shown an increased risk of type 2 diabetes in general populations exposed to arsenic, but little is known about exposures during pregnancy and the association with gestational diabetes ...
Associations of Early Childhood Manganese and Lead Coexposure with Neurodevelopment
(National Institute of Environmental Health Sciences, 2011)
Background: Most toxicologic studies focus on a single agent, although this does not reflect real-world scenarios in which humans are exposed to multiple chemicals. Objectives: We prospectively studied manganese–lead ...