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Blood Epigenetic Age may Predict Cancer Incidence and Mortality
(Elsevier, 2016)
Biological measures of aging are important for understanding the health of an aging population, with epigenetics particularly promising. Previous studies found that tumor tissue is epigenetically older than its donors are ...
Blood Telomere Length Attrition and Cancer Development in the Normative Aging Study Cohort
(Elsevier, 2015)
Background: Accelerated telomere shortening may cause cancer via chromosomal instability, making it a potentially useful biomarker. However, publications on blood telomere length (BTL) and cancer are inconsistent. We ...
Effects of particulate matter exposure on blood 5-hydroxymethylation: results from the Beijing truck driver air pollution study
(Taylor & Francis, 2015)
Previous studies have reported epigenetic changes induced by environmental exposures. However, previous investigations did not distinguish 5-methylcytosine (5mC) from a similar oxidative form with opposite functions, ...
Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study
(National Institute of Environmental Health Sciences, 2015)
Background: MicroRNAs (miRNAs) are post-transcriptional gene suppressors and potential mediators of environmental effects. In addition to human miRNAs, viral miRNAs expressed from latent viral sequences are detectable in ...