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Direct Assessment of Cumulative Aryl Hydrocarbon Receptor Agonist Activity in Sera from Experimentally Exposed Mice and Environmentally Exposed Humans
(National Institute of Environmental Health Sciences, 2009)
Background: Aryl hydrocarbon receptor (AhR) ligands adversely affect many biological processes. However, assessment of the significance of human exposures is hampered by an incomplete understanding of how complex mixtures ...
Assessment of Xenoestrogenic Exposure by a Biomarker Approach: Application of the E-Screen Bioassay to Determine Estrogenic Response of Serum Extracts
(BioMed Central, 2003)
Background: Epidemiological documentation of endocrine disruption is complicated by imprecise exposure assessment, especially when exposures are mixed. Even if the estrogenic activity of all compounds were known, the ...
Methylmercury Exposure and Adverse Cardiovascular Effects in Faroese Whaling Men
(National Institute of Environmental Health Sciences, 2008)
Background: Methylmercury (MeHg), a worldwide contaminant found in fish and seafood, has been linked to an increased risk of cardiovascular mortality. Objective: We examined 42 Faroese whaling men (30–70 years of age) to ...
Separation of Risks and Benefits of Seafood Intake
(National Institute of Environmental Health Sciences, 2006)
Background: Fish and seafood provide important nutrients but may also contain toxic contaminants, such as methylmercury. Advisories against pollutants may therefore conflict with dietary recommendations. In resolving this ...
Concentrations of Polybrominated Diphenyl Ethers, Polychlorinated Biphenyls, and Polychlorobiphenylols in Serum from Pregnant Faroese Women and Their Children 7 Years Later
(American Chemical Society (ACS), 2005)
The objective of this study was to assess blood concentrations of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs), and their polychlorobiphenylol (OH-PCB) metabolites in humans with a high seafood ...
Serum polychlorinated biphenyl and organochlorine insecticide concentrations in a Faroese birth cohort
(Elsevier BV, 2006)
A prospective birth cohort of 1022 participants was established in the Faroe Islands over a 21-month period during 1986–1987. We collected questionnaire data on potential persistent organic pollutant (POP) concentration ...
Association between mercury concentrations in blood and hair in methylmercury-exposed subjects at different ages
(Elsevier BV, 2004)
Mercury concentrations were measured in paired hair and blood samples from a cohort of about 1000 children examined at birth and at 7 and 14 years of age. The ratio between concentrations in maternal hair (in μg/g) and in ...
Application of hair-mercury analysis to determine the impact of a seafood advisory
(Elsevier BV, 2005)
Following an official recommendation in the Faroe Islands that women should abstain from eating mercury-contaminated pilot whale meat, a survey was carried out to obtain information on dietary habits and hair samples for ...
Maternal seafood diet, methylmercury exposure, and neonatal neurologic function
(Elsevier BV, 2000)
Objective: To determine whether neonatal neurologic function is adversely affected by seafood contaminants from maternal diet during pregnancy.
Study design: One hundred eighty-two singleton term births were evaluated in ...
Cardiac autonomic activity in methylmercury neurotoxicity: 14-year follow-up of a Faroese birth cohort
(Elsevier BV, 2004)
Objective
To determine whether heart function in childhood is affected by exposure to methylmercury (MeHg) from seafood.
Study design
Prospective study of a Faroese birth cohort (N = 1022). Examinations at ages 7 ...