Search
Now showing items 1-4 of 4
Use of Cumulative Incidence of Novel Influenza A/H1N1 in Foreign Travelers to Estimate Lower Bounds on Cumulative Incidence in Mexico
(Public Library of Science, 2009)
Background: An accurate estimate of the total number of cases and severity of illness of an emerging infectious disease is required both to define the burden of the epidemic and to determine the severity of disease. When ...
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum
(BioMed Central, 2009)
Background: The identification of genetic changes that confer drug resistance or other phenotypic changes in
pathogens can help optimize treatment strategies, support the development of new therapeutic agents, and
provide ...
Tumor dormancy and surgery-driven interruption of dormancy in breast cancer: learning from failures
(Nature Publishing Group, 2007)
Primary tumor removal, usually considered intrinsically beneficial, can perturb metastatic homeostasis, and for some patients results in the acceleration of metastatic cancer. The continuous-growth model is required to ...
Dormancy and surgery-driven escape from dormancy help explain some clinical features of breast cancer
(Wiley-Blackwell, 2008)
To explain bimodal relapse patterns observed in breast cancer data, we have proposed that metastatic breast cancer growth commonly includes periods of temporary dormancy at both the single cell phase and the avascular ...