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Blood Epigenetic Age may Predict Cancer Incidence and Mortality
Biological measures of aging are important for understanding the health of an aging population, with epigenetics particularly promising. Previous studies found that tumor tissue is epigenetically older than its donors are ...
DNA methylation-based measures of biological age: meta-analysis predicting time to death
(Impact Journals LLC, 2016)
Estimates of biological age based on DNA methylation patterns, often referred to as “epigenetic age”, “DNAm age”, have been shown to be robust biomarkers of age in humans. We previously demonstrated that independent of ...
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases
(BioMed Central, 2016)
Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis of complex diseases. Identifying genetic loci where DNA methylation is associated with chronic low-grade ...