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Hospital Acquired Pneumonia Is Linked to Right Hemispheric Peri-Insular Stroke
(Public Library of Science, 2013)
Purpose Hospital acquired pneumonia (HAP) is a major complication of stroke. We sought to determine associations between infarction of specific brain regions and HAP. Methods: 215 consecutive acute stroke patients with HAP ...
Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
(Public Library of Science, 2013)
Numerous obesity loci have been identified using genome-wide association studies. A UK study indicated that physical activity may attenuate the cumulative effect of 12 of these loci, but replication studies are lacking. ...
Frequent Intra-Subtype Recombination among HIV-1 Circulating in Tanzania
(Public Library of Science, 2013)
The study estimated the prevalence of HIV-1 intra-subtype recombinant variants among female bar and hotel workers in Tanzania. While intra-subtype recombination occurs in HIV-1, it is generally underestimated. HIV-1 env ...
Multiplex PCR System for Rapid Detection of Pathogens in Patients with Presumed Sepsis – A Systemic Review and Meta-Analysis
(Public Library of Science, 2013)
Background: Blood culture is viewed as the golden standard for the diagnosis of sepsis but suffers from low sensitivity and long turnaround time. LightCycler SeptiFast (LC-SF) is a real-time multiplex polymerase chain ...
Harnessing the Medicaid Analytic eXtract (MAX) to Evaluate Medications in Pregnancy: Design Considerations
(Public Library of Science, 2013)
Background: In the absence of clinical trial data, large post-marketing observational studies are essential to evaluate the safety and effectiveness of medications during pregnancy. We identified a cohort of pregnancies ...
Joint Association of Dietary Pattern and Physical Activity Level with Cardiovascular Disease Risk Factors among Chinese Men: A Cross-Sectional Study
(Public Library of Science, 2013)
The purpose of this cross-sectional study was to investigate the joint associations of physical activity level (PAL) and dietary patterns in relation to cardiovascular disease (CVD) risk factors among Chinese men. The study ...
Population Trends and Variation in Body Mass Index from 1971 to 2008 in the Framingham Heart Study Offspring Cohort
(Public Library of Science, 2013)
Objective: We examined body mass index (BMI) across place and time to determine the pattern of BMI mean and standard deviation trajectories. Methods: We included participants in the Framingham Heart Study (FHS) Offspring ...
Effectiveness of Patient Adherence Groups as a Model of Care for Stable Patients on Antiretroviral Therapy in Khayelitsha, Cape Town, South Africa
(Public Library of Science, 2013)
Background: Innovative models of care are required to cope with the ever-increasing number of patients on antiretroviral therapy in the most affected countries. This study, in Khayelitsha, South Africa, evaluates the ...
Network-Level Structural Abnormalities of Cerebral Cortex in Type 1 Diabetes Mellitus
(Public Library of Science, 2013)
Type 1 diabetes mellitus (T1DM) usually begins in childhood and adolescence and causes lifelong damage to several major organs including the brain. Despite increasing evidence of T1DM-induced structural deficits in cortical ...
Association of pol Diversity with Antiretroviral Treatment Outcomes among HIV-Infected African Children
(Public Library of Science, 2013)
Background: In HIV-infected children, viral diversity tends to increase with age in the absence of antiretroviral treatment (ART). We measured HIV diversity in African children (ages 6–36 months) enrolled in a randomized ...