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Estimating the Global Prevalence of Inadequate Zinc Intake from National Food Balance Sheets: Effects of Methodological Assumptions
(Public Library of Science, 2012)
Background: The prevalence of inadequate zinc intake in a population can be estimated by comparing the zinc content of the food supply with the population’s theoretical requirement for zinc. However, assumptions regarding ...
What Drives the US and Peruvian HIV Epidemics in Men Who Have Sex with Men (MSM)?
(Public Library of Science, 2012)
In this work, we estimate the proportions of transmissions occurring in main vs. casual partnerships, and by the sexual role, infection stage, and testing and treatment history of the infected partner, for men who have sex ...
Inflammation and Immune-Related Candidate Gene Associations with Acute Lung Injury Susceptibility and Severity: A Validation Study
(Public Library of Science, 2012)
Introduction: Common variants in genes related to inflammation, innate immunity, epithelial cell function, and angiogenesis have been reported to be associated with risks for Acute Lung Injury (ALI) and related outcomes. ...
Urinary Benzene Biomarkers and DNA Methylation in Bulgarian Petrochemical Workers: Study Findings and Comparison of Linear and Beta Regression Models
(Public Library of Science, 2012)
Chronic occupational exposure to benzene is associated with an increased risk of hematological malignancies such as acute myeloid leukemia (AML), but the underlying mechanisms are still unclear. The main objective of this ...
Bioinformatics for the Human Microbiome Project
(Public Library of Science, 2012)
Participation in Sports Organizations and the Prevention of Functional Disability in Older Japanese: The AGES Cohort Study
(Public Library of Science, 2012)
Background: We sought to examine prospectively the difference in the association between incident functional disability and exercise with or without sports organization participation. Methods: The study was based on the ...
Zcchc11 Uridylates Mature miRNAs to Enhance Neonatal IGF-1 Expression, Growth, and Survival
(Public Library of Science, 2012)
The Zcchc11 enzyme is implicated in microRNA (miRNA) regulation. It can uridylate let-7 precursors to decrease quantities of the mature miRNA in embryonic stem cell lines, suggested to mediate stem cell maintenance. It can ...
White Blood Cell Count and the Risk for Coronary Artery Disease in Young Adults
(Public Library of Science, 2012)
Background: The association between white blood cell (WBC) count and coronary artery disease (CAD) is unknown in young adults. Our objective was to assess the association between WBC count and its changes over time with ...
Co-Operative Additive Effects between HLA Alleles in Control of HIV-1
(Public Library of Science, 2012)
Background: HLA class I genotype is a major determinant of the outcome of HIV infection, and the impact of certain alleles on HIV disease outcome is well studied. Recent studies have demonstrated that certain HLA class I ...
Identification of FAM111A as an SV40 Host Range Restriction and Adenovirus Helper Factor
(Public Library of Science, 2012)
The small genome of polyomaviruses encodes a limited number of proteins that are highly dependent on interactions with host cell proteins for efficient viral replication. The SV40 large T antigen (LT) contains several ...