Search
Now showing items 1-10 of 13
Exposure to sub-chronic and long-term particulate air pollution and heart rate variability in an elderly cohort: the Normative Aging Study
(BioMed Central, 2015)
Background: Short-term particulate air pollution exposure is associated with reduced heart rate variability (HRV), a risk factor for cardiovascular morbidity and mortality, in many studies. Associations with sub-chronic ...
The Association of Meningococcal Disease with Influenza in the United States, 1989–2009
(Public Library of Science, 2014)
Importance and Objective Prior influenza infection is a risk factor for invasive meningococcal disease. Quantifying the fraction of meningococcal disease attributable to influenza could improve understanding of viral-bacterial ...
A Novel Genetic Score Approach Using Instruments to Investigate Interactions between Pathways and Environment: Application to Air Pollution
(Public Library of Science, 2014)
Air pollution has been associated with increased systemic inflammation markers. We developed a new pathway analysis approach to investigate whether gene variants within relevant pathways (oxidative stress, endothelial ...
Associations between Changes in City and Address Specific Temperature and QT Interval - The VA Normative Aging Study
(Public Library of Science, 2014)
Background: The underlying mechanisms of the association between ambient temperature and cardiovascular morbidity and mortality are not well understood, particularly for daily temperature variability. We evaluated if daily ...
Short-Term Changes in Ambient Temperature and Risk of Ischemic Stroke
(S. Karger AG, 2014)
Background: Despite consistent evidence of a higher short-term risk of cardiovascular mortality associated with ambient temperature, there have been discrepant findings on the association between temperature and ischemic ...
Short Term Effects of Particle Exposure on Hospital Admissions in the Mid-Atlantic States: A Population Estimate
(Public Library of Science, 2014)
Background: Many studies report significant associations between PM2.5 (particulate matter <2.5 micrometers) and hospital admissions. These studies mostly rely on a limited number of monitors which introduces exposure ...
Searching for Sharp Drops in the Incidence of Pandemic A/H1N1 Influenza by Single Year of Age
(Public Library of Science, 2012)
Background: During the 2009 H1N1 pandemic (pH1N1), morbidity and mortality sparing was observed among the elderly population; it was hypothesized that this age group benefited from immunity to pH1N1 due to cross-reactive ...
Using New Satellite Based Exposure Methods to Study the Association between Pregnancy PM\(_{2.5}\) Exposure, Premature Birth and Birth Weight in Massachusetts
(BioMed Central, 2012)
Background: Adverse birth outcomes such as low birth weight and premature birth have been previously linked with exposure to ambient air pollution. Most studies relied on a limited number of monitors in the region of ...
Alu and LINE-1 methylation and lung function in the normative ageing study
(BMJ Publishing Group, 2012)
Objectives: To investigate the association between methylation of transposable elements Alu and long-interspersed nuclear elements (LINE-1) and lung function. Design: Cohort study. Setting: Outpatient Veterans Administration ...
Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study
(BioMed Central, 2013)
Background: Previous studies found effect modification of associations between traffic-related air pollution and cardiovascular outcomes by polymorphisms in the hemochromatosis gene (HFE). As traffic-related air pollution ...