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Increased Risk of Paroxysmal Atrial Fibrillation Episodes Associated with Acute Increases in Ambient Air Pollution
(National Institute of Environmental Health Sciences, 2006)
Objectives: We reported previously that 24-hr moving average ambient air pollution concentrations were positively associated with ventricular arrhythmias detected by implantable cardioverter defibrillators (ICDs). ICDs ...
Lead Levels and Ischemic Heart Disease in a Prospective Study of Middle-Aged and Elderly Men: The VA Normative Aging Study
(National Institute of Environmental Health Sciences, 2007)
Background: Lead exposure has been associated with higher blood pressure, hypertension, electrocardiogram abnormalities, and increased mortality from circulatory causes.Objective We assessed the association between bone ...
Cumulative Exposure to Lead in Relation to Cognitive Function in Older Women
(National Institute of Environmental Health Sciences, 2008)
Background: Recent data indicate that chronic low-level exposure to lead is associated with accelerated declines in cognition in older age, but this has not been examined in women. Objective: We examined biomarkers of lead ...
Black Carbon Exposure, Oxidative Stress Genes, and Blood Pressure in a Repeated-measures Study
(National Institute of Environmental Health Sciences, 2009)
Background: Particulate matter (PM) air pollution has been associated with cardiovascular morbidity and mortality, and elevated blood pressure (BP) is a known risk factor for cardiovascular disease. A small number of studies ...
Factors Affecting the Association between Ambient Concentrations and Personal Exposures to Particles and Gases
(National Institute of Environmental Health Sciences, 2005)
Results from air pollution exposure assessment studies suggest that ambient fine particles [particulate matter with aerodynamic diameter ≤ 2.5 μg (PM2.5)], but not ambient gases, are strong proxies of corresponding personal ...
Acute and Chronic Effects of Particles on Hospital Admissions in New England
(Public Library of Science, 2012)
Background: Many studies have reported significant associations between exposure to \(PM_{2.5}\) and hospital admissions, but all have focused on the effects of short-term exposure. In addition all these studies have relied ...
Opposing Effects of Particle Pollution, Ozone, and Ambient Temperature on Arterial Blood Pressure
(National Institute of Environmental Health Sciences, 2012)
Background: Diabetes increases the risk of hypertension and orthostatic hypotension and raises the risk of cardiovascular death during heat waves and high pollution episodes. Objective: We examined whether short-term ...
Modifying Effects of the HFE Polymorphisms on the Association Between Lead Burden and Cognitive Decline
(National Institute of Environmental Health Sciences, 2007)
Background: As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship. Objective: ...
Baseline Repeated Measures from Controlled Human Exposure Studies: Associations between Ambient Air Pollution Exposure and the Systemic Inflammatory Biomarkers IL-6 and Fibrinogen
(National Institute of Environmental Health Sciences, 2009)
Introduction: Systemic inflammation may be one of the mechanisms mediating the association between ambient air pollution and cardiovascular morbidity and mortality. Interleukin-6 (IL-6) and fibrinogen are biomarkers of ...
Cumulative Community-Level Lead Exposure and Pulse Pressure: The Normative Aging Study
(National Institute of Environmental Health Sciences, 2007)
Background: Pulse pressure increases with age in industrialized societies as a manifestation of arterial stiffening. Lead accumulates in the vasculature and is associated with vascular oxidative stress, which can promote ...