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A Novel Genetic Score Approach Using Instruments to Investigate Interactions between Pathways and Environment: Application to Air Pollution
(Public Library of Science, 2014)
Air pollution has been associated with increased systemic inflammation markers. We developed a new pathway analysis approach to investigate whether gene variants within relevant pathways (oxidative stress, endothelial ...
Short Term Effects of Particle Exposure on Hospital Admissions in the Mid-Atlantic States: A Population Estimate
(Public Library of Science, 2014)
Background: Many studies report significant associations between PM2.5 (particulate matter <2.5 micrometers) and hospital admissions. These studies mostly rely on a limited number of monitors which introduces exposure ...
Using New Satellite Based Exposure Methods to Study the Association between Pregnancy PM\(_{2.5}\) Exposure, Premature Birth and Birth Weight in Massachusetts
(BioMed Central, 2012)
Background: Adverse birth outcomes such as low birth weight and premature birth have been previously linked with exposure to ambient air pollution. Most studies relied on a limited number of monitors in the region of ...
Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study
(BioMed Central, 2013)
Background: Previous studies found effect modification of associations between traffic-related air pollution and cardiovascular outcomes by polymorphisms in the hemochromatosis gene (HFE). As traffic-related air pollution ...
Exposure to sub-chronic and long-term particulate air pollution and heart rate variability in an elderly cohort: the Normative Aging Study
(BioMed Central, 2015)
Background: Short-term particulate air pollution exposure is associated with reduced heart rate variability (HRV), a risk factor for cardiovascular morbidity and mortality, in many studies. Associations with sub-chronic ...
Associations between Changes in City and Address Specific Temperature and QT Interval - The VA Normative Aging Study
(Public Library of Science, 2014)
Background: The underlying mechanisms of the association between ambient temperature and cardiovascular morbidity and mortality are not well understood, particularly for daily temperature variability. We evaluated if daily ...
Short‐Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study
(John Wiley and Sons Inc., 2016)
Background: Short‐term exposure to elevated air pollution has been associated with higher risk of acute cardiovascular diseases, with systemic oxidative stress induced by air pollution hypothesized as an important underlying ...