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Air pollution exposure and gestational diabetes mellitus among pregnant women in Massachusetts: a cohort study
(BioMed Central, 2016)
Background: Rodent and human studies suggest an association between air pollution exposure and type 2 diabetes mellitus, but the extent to which air pollution is associated with gestational diabetes mellitus (GDM) is less ...
Effects of particulate matter exposure on blood 5-hydroxymethylation: results from the Beijing truck driver air pollution study
(Taylor & Francis, 2015)
Previous studies have reported epigenetic changes induced by environmental exposures. However, previous investigations did not distinguish 5-methylcytosine (5mC) from a similar oxidative form with opposite functions, ...
Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals
(BioMed Central, 2016)
Background: Air pollution from particulate matter (PM) has been linked to cardiovascular morbidity and mortality; however the underlying biological mechanisms remain to be uncovered. Gene regulation by microRNAs (miRNAs) ...
Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study
(National Institute of Environmental Health Sciences, 2015)
Background: MicroRNAs (miRNAs) are post-transcriptional gene suppressors and potential mediators of environmental effects. In addition to human miRNAs, viral miRNAs expressed from latent viral sequences are detectable in ...
Associations of Fine Particulate Matter Species with Mortality in the United States: A Multicity Time-Series Analysis
(NLM-Export, 2014)
Background: Epidemiological studies have examined the association between PM2.5 and mortality, but uncertainty remains about the seasonal variations in PM2.5-related effects and the relative importance of species. Objectives: ...
Air pollution exposure and lung function in highly exposed subjects in Beijing, China: a repeated-measure study
(BioMed Central, 2014)
Background: Exposure to ambient particulate matter (PM) has been associated with reduced lung function. Elemental components of PM have been suggested to have critical roles in PM toxicity, but their contribution to ...
The Association of Meningococcal Disease with Influenza in the United States, 1989–2009
(Public Library of Science, 2014)
Importance and Objective Prior influenza infection is a risk factor for invasive meningococcal disease. Quantifying the fraction of meningococcal disease attributable to influenza could improve understanding of viral-bacterial ...
Estimating Causal Effects of Local Air Pollution on Daily Deaths: Effect of Low Levels
(National Institute of Environmental Health Sciences, 2016)
Background: Although many time-series studies have established associations of daily pollution variations with daily deaths, there are fewer at low concentrations, or focused on locally generated pollution, which is becoming ...
Long-term ambient particle exposures and blood DNA methylation age: findings from the VA normative aging study
(2016)
Background: Ambient particles have been shown to exacerbate measures of biological aging; yet, no studies have examined their relationships with DNA methylation age (DNAm-age), an epigenome-wide DNA methylation based ...
Chronic effects of temperature on mortality in the Southeastern USA using satellite-based exposure metrics
(Nature Publishing Group, 2016)
Climate change may affect human health, particularly for elderly individuals who are vulnerable to temperature changes. While many studies have investigated the acute effects of heat, only a few have dealt with the chronic ...